2.Root canal treatment of type Ⅱ and ⅢA double dens invaginatus in maxillary lateral incisor: a case report.
West China Journal of Stomatology 2023;41(2):232-236
Dens invaginatus is a rare developmental anomaly of the teeth that is caused by the infolding of enamel organs or the penetration of their proliferations into dental papillae before calcification has occurred. The presence of double dens invaginatus is extremely rare. This paper describes the use of cone beam computed tomography in the evaluation of a maxillary lateral incisor with double dens invaginatus and periapical periodontitis. The tooth was treated through microscopic root canal therapy. The tooth was free of clinical symptoms, and the periradicular lesion narrowed during the follow-up period of 1 year.
Humans
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Dental Pulp Cavity/abnormalities*
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Dens in Dente/pathology*
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Incisor/pathology*
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Root Canal Therapy
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Periapical Periodontitis/pathology*
3.Problem solving in endodontic diseases: V. Correlation of clinical diagnosis, prognosis and histopathologic signs of apical periodontitis (I).
Chinese Journal of Stomatology 2010;45(3):177-181
Acute Disease
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Anti-Bacterial Agents
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therapeutic use
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Chronic Disease
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Disinfectants
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therapeutic use
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Humans
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Periapical Abscess
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diagnosis
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therapy
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Periapical Granuloma
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diagnosis
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therapy
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Periapical Periodontitis
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classification
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diagnosis
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pathology
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therapy
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Problem Solving
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Prognosis
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Root Canal Irrigants
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therapeutic use
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Root Canal Therapy
4.Expression of interleukin-17F in human apical periodontitis lesions.
Chinese Journal of Stomatology 2012;47(6):345-349
OBJECTIVETo examine the expression of interleukin-17F (IL-17F) in apical periodontitis lesions.
METHODSHuman apical periodontitis lesions were collected after periapical surgery from November 1, 2009 to August 1, 2011. After histological processing, serial sectioning, HE staining, and microscopic analysis, 33 periapical cysts and 18 periapical granulomas were selected for immunohistochemical analysis for IL-17F. Five alveolar bone samples were obtained from a group of impacted third molars recommended for extraction. These bone samples did not show any inflammation and were used as normal samples. Differences in IL-17F expression between the tissues with periapical cyst and periapica granuloma were subsequently analyzed by rank-sum test.
RESULTSIL-17F was expressed in epithelial cells, lymphocytes, fibroblast and endothelial cells of both types of lesions. Both types of lesions presented increased IL-17F expression when compared to healthy periapical alveolar bone. The expression of IL-17F in apical cyst (0.2365 ± 0.0708) and apical granuloma (0.8852 ± 0.0576) was significantly different (Z = 3.735, P < 0.01).
CONCLUSIONSIL-17F could be observed and might be involved in the inflammatory response and bone resorption of periapical tissues. The expression of IL-17F in periapical cyst and periapical granuloma was significantly different.
Adult ; Endothelial Cells ; metabolism ; Epithelial Cells ; metabolism ; Female ; Fibroblasts ; metabolism ; Humans ; Interleukin-17 ; metabolism ; Lymphocytes ; metabolism ; Male ; Periapical Granuloma ; metabolism ; pathology ; Periapical Periodontitis ; metabolism ; pathology ; Radicular Cyst ; metabolism ; pathology
5.Expression of lipopolysaccharide receptors CD14 and TLR4 in a model of rat molar apical periodontitis.
Chinese Journal of Stomatology 2007;42(3):148-149
OBJECTIVETo characterize the expression of lipopolysaccharide (LPS) receptors-CD14 and TLR4 in rat peri-radicular tissue and to investigate the signal transduction pathway of LPS and its receptors in periapical periodontitis.
METHODSAfter establishment of a model of rat molar LPS-induced apical periodontitis, CD14 and TLR4 expression in healthy and inflammatory periapical tissue were determined by immunohistochemistry.
RESULTSCD14 and TLR4 were not detected in healthy periapical tissue but strongly positive in inflammatory periapical tissue. Positive cells were mostly monocytes/macrophages.
CONCLUSIONSCD14 and TLR4 may play an important role in the pathogenesis of periapical periodontitis, probably via immune cells such as monocytes/macrophages and neutrophils.
Animals ; Disease Models, Animal ; Lipopolysaccharide Receptors ; metabolism ; Lipopolysaccharides ; toxicity ; Periapical Periodontitis ; chemically induced ; metabolism ; pathology ; Rats ; Rats, Sprague-Dawley ; Signal Transduction ; Toll-Like Receptor 4 ; metabolism
6.Maxillary first molar with an O-shaped root morphology: report of a case.
Yooseok SHIN ; Yemi KIM ; Byoung-Duck ROH
International Journal of Oral Science 2013;5(4):242-244
This case report is to present a maxillary first molar with one O-shaped root, which is an extended C-shaped canal system. Patient with chronic apical periodontitis in maxillary left first molar underwent replantation because of difficulty in negotiating all canals. Periapical radiographs and cone-beam computed tomography (CBCT) were taken. All roots were connected and fused to one root, and all canals seemed to be connected to form an O-shape. The apical 3 mm of the root were resected and retrograde filled with resin-modified glass ionomer. Intentional replantation as an alternative treatment could be considered in a maxillary first molar having an unusual O-shaped root.
Adult
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Anatomic Variation
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Apicoectomy
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methods
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Cone-Beam Computed Tomography
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methods
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Dental Pulp Cavity
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diagnostic imaging
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pathology
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Glass Ionomer Cements
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therapeutic use
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Humans
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Male
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Maxilla
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Molar
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diagnostic imaging
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pathology
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Periapical Periodontitis
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therapy
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Retrograde Obturation
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methods
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Root Canal Filling Materials
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therapeutic use
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Root Canal Preparation
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methods
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Tooth Replantation
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methods