No abstract available.
Breast ; Peptococcus

Renal and perinephric abscess are uncommon diseases with a multitude of clinical presentations. In past morbidity and mortality were high rate because of delay in diagnosis. Diagnosis and treatment approaches were challenged recently by newer imaging modalities as ultrasonography and CT scanning and by interventional uroradiology. A clinical observation was made in 9 patients with renal abscess and 1O patients with perinephric abscess admitted in the Dept. of Urology, Kyung Hee University Hospital during the period from Jan. 1981 to Jan. 1986. The following results were observed: 1. Among 19 patients, 11 patients were women and their age was ranged from 22 to 68 yrs old with mean of 44.5 yrs. In 12 cases, Lt. kidneys were involved. 2. In 5 patients who had positive urine culture, E. coli was recovered in 3 cases, and klebsiella sp. and staph. epldermidis were recovered in one case, respectively. Blood culture was positive in one case. Among 14 cases performed pus culture, bacteria was recovered in 8 cases: E. coli in 4 cases staph. aureus in 2 cases, and staph. epldermidis and peptococcus in one case, respectively. 3. In 15 cases, diagnosis could be confirmed by ultrasonography, but CT scan was needed in 4 cases to confirm the nature of lesion. The common findings of ultrasonogram were mixed echogenic mass and echolucent mass found in 8 cases and 7 cases, respectively. 4. Among 19 cases, 1O patients underwent open drainage, 5 cases were treated by antibiotics only, and 3 cases were managed successfully by closed drainage.
Abscess* ; Anti-Bacterial Agents ; Bacteria ; Diagnosis ; Drainage ; Female ; Humans ; Kidney ; Klebsiella ; Mortality ; Peptococcus ; Suppuration ; Tomography, X-Ray Computed ; Ultrasonography ; Urology

OBJECTIVETo investigate the changes in fecal flora and its correlation with the occurrence and progression of inflammatory bowel disease (IBD).

METHODSWe collected fresh fecal specimens from 167 IBD patients (including 113 with ulcerative colitis and 54 with Crohn's disease) and 54 healthy volunteers. The fecal flora was analyzed by gradient dilution method and the data of inflammatory markers including WBC, PLT, CRP and ESR were collected to assess the association between the fecal flora and the inflammatory markers.

RESULTSThe species Enterrococcus (6.60∓0.23, P<0.01), Saccharomyces (2.22∓0.27, P<0.05), Bacteriodes (5.57∓0.28, P<0.001), Bifidobacterium (5.08∓0.30, P<0.01), Peptococcus (6.22∓0.25, P<0.001), Lactobacillus (6.00∓0.26, P<0.001), and Clostridium (3.57∓0.30, P<0.05) all increased significantly, while Eubacterium (1.56∓0.24, P<0.01) reduced markedly in patients with ulcerative colitis compared with those in the control subjects. Enterrococcus (6.93∓0.28, P<0.01), Saccharomyces (2.73∓0.37, P<0.01), Bacteriodes (4.32∓0.52, P<0.05), Bifidobacterium (4.88∓0.42, P<0.05), Peptococcus (6.19∓0.32, P<0.01) and Lactobacillus (4.73∓0.47, P<0.001) all increased significantly and Eubacterium (1.01∓0.29, P<0.01) and Clostridium (0.87∓0.31, P<0.01) decreased in patients with Crohn's disease. The positivity rates of bacterial culture were consistent with the results of quantitative analysis of the fecal flora. The changes in fecal flora did not show a significant correlation with these inflammatory markers.

CONCLUSIONIBD patients have fecal flora imbalance compared with the healthy controls, and this imbalance may contribute to the occurrence and progression of IBD. The decline of Eubacterium contributes to the occurrence and development of IBD.

Adult ; Bacteria ; isolation & purification ; Bacteroides ; isolation & purification ; Bifidobacterium ; isolation & purification ; Biomarkers ; analysis ; Clostridium ; isolation & purification ; Colitis, Ulcerative ; microbiology ; Crohn Disease ; microbiology ; Enterococcus ; isolation & purification ; Eubacterium ; isolation & purification ; Feces ; microbiology ; Female ; Humans ; Inflammatory Bowel Diseases ; etiology ; microbiology ; Lactobacillus ; isolation & purification ; Male ; Peptococcus ; isolation & purification ; Saccharomyces ; isolation & purification