OBJECTIVETo investigate the chemical constituents of Peperomia tetraphylla.

METHODThe constituents of EtOAc-soluble portion were isolated and purified by chromatography. Their structures were identified by spectral features.

RESULTSix amides were isolated and identified as, aristololactam All (1), aristololactam B II (2), N-trans-feruloyltyramine (3), N-trans-sinapoyltyramine (4), N-trans-feruloylmethoxytyramine (5), N-p-coumaroyltyramine (6).

CONCLUSIONAll compounds were isolated from this plant for the first time.

Amides ; analysis ; Peperomia ; chemistry ; Plant Extracts ; analysis

In 2010, symptoms of leaf and stem rot were observed on potted plants (Peperomia quadrangularis) in a greenhouse in Yongin, Korea. The causative pathogen was identified as Myrothecium roridum based on morphological data, internal transcribed spacer sequence analysis, and pathogenicity test. To our knowledge, this is the first report of M. roridum causing leaf and stem rot disease on P. quadrangularis in Korea and elsewhere worldwide.
Gyeonggi-do ; Korea ; Peperomia* ; Sequence Analysis ; Virulence

Peperomia pellucida (L.) Kunth is a medicinal plant used to manage inflammatory illnesses such as conjunctivitis, and gastrointestinal and respiratory tract disorders in tropical and subtropical regions. However, little is known about its pharmacological mechanism of action against eye diseases. This review aims to critically discuss the phytochemistry, pharmacology and toxicology of P. pellucida as well as its roles in the treatment of cataract, glaucoma and diabetic retinopathy. Recent developments in the uses of P. pellucida for healthcare and nutraceutical products by the pharmaceutical industry are also covered in this review. For this review, a literature search was performed with PubMed, ScienceDirect, SciFinder Scholar and Scopus databases, using relevant keywords. Among the various phytochemicals identified from P. pellucida, β-caryophyllene, carotol, dillapiole, ellagic acid, pellucidin A, phytol and vitexin exhibit strong pharmacological activities within the mitogen-activated protein kinase and nuclear factor-κB signalling pathways in inflammatory eye diseases. The antihypertensive, anti-inflammatory, antioxidant, antihyperglycemic and anti-angiogenic activities displayed by P. pellucida extracts in many in vitro, in vivo and clinical studies suggest its potential role in the management of inflammatory eye diseases. P. pellucida extract was non-toxic against normal cell lines but displayed mild toxicity in animal models. The growing public interest in P. pellucida has inspired the nutraceutical and pharmaceutical industries to process the plant into health products. Although the potential pharmacological mechanisms against eye diseases have been summarized, further studies of the interactions among constituent phytochemicals from P. pellucida within various signalling pathways shall support the use of the plant as an alternative therapeutic source.
Animals ; Ethnopharmacology ; Eye Diseases/drug therapy* ; Peperomia ; Phytochemicals/therapeutic use* ; Phytotherapy ; Plant Extracts/therapeutic use* ; Plants, Medicinal

OBJECTIVETo study the chemical constituents of Peperomia dindygulensis.

METHODSeveral column chromatographic methods were used to isolated compounds from P. dindygulensis and spectroscopic methods (1H-NMR, 13C-NMR, HMQC, HMBC, 1D- HOHAHA, NOE) were used to identify the structures of isolated compounds.

RESULTCompound 1 was isolated and identified as 2"-O-beta-D-galactosylisoswertisin.

CONCLUSIONCompound 1 was a new compound.

Chromatography, Affinity ; Drugs, Chinese Herbal ; chemistry ; Flavones ; analysis ; isolation & purification ; Galactosides ; analysis ; isolation & purification ; Magnetic Resonance Spectroscopy ; Peperomia ; chemistry ; Porosity

To study the chemical constituents of Peperomia dindygulensis Miq. , chromatography was used to isolate and purify the chemical constituents, their structures were elucidated by spectroscopic data and physical-chemical properties. Three compounds were obtained. They were identified as: hypolacetin-4',7-dimethyl ether-8-O-beta-D-glucopyranoside (I) , isoscutellarein-4'-methyl ether-8-O-alpha-L-arabinopyrano-syl-(1--> 4)-beta-D-glucopyranoside ( II) , isoscutellarein-4', 7-dimethyl ether-8-O-alpha-L-arabinopyranosyl-(1-->4) -betea-D-glucopyranoside (III). Compounds I, II and III are all new compounds.
Disaccharides ; chemistry ; isolation & purification ; Flavones ; chemistry ; isolation & purification ; Flavonoids ; chemistry ; isolation & purification ; Glucosides ; chemistry ; isolation & purification ; Glycosides ; chemistry ; isolation & purification ; Molecular Structure ; Peperomia ; chemistry ; Plants, Medicinal ; chemistry