OBJECTIVESTo evaluate the clinic value of doppler ultrasonography in diagnosis of vasculogenic erectile dysfunction (ED).

METHODSThe hemodynamic change was obsreved by doppler ultrasonography during the erection of penis and the results between patients with vasculogenic ED and controls were compared. The doppler ultrasonographic characteristics of vascular ED was analyzed.

RESULTSIn the patients with arterial ED the peak systolic velocity(PSV) in deep artery was apparently lower than controls(P < 0.01), and in the patients with venous ED, the velocity of deep dorsal vein was higher during complete erection than controls(P < 0.05).

CONCLUSIONSThe result of doppler ultrasonography examination effectively helps the diagnosis of vasculogenic.

Adult ; Humans ; Impotence, Vasculogenic ; diagnostic imaging ; Male ; Penis ; blood supply ; Regional Blood Flow ; Ultrasonography, Doppler, Color

This report describes the color and pulsed Doppler US findings of penile Mondor's disease. The pulsed Doppler US findings of penile Mondor's disease have not been previously published, so we report here for the first time on the cavernosal arterial flow signal pattern of penile Mondor's disease. Penile Mondor's disease is rare disease that's characterized by thrombosis in the dorsal vein of the penis. The previous reports on penile Mondor's disease are concerned with the color Doppler US finding without the flow signals in this area, but these findings are insufficient to understand the hemodynamics in penile Mondor's disease. We report for the first time on a cavernosal artery flow signal pattern of low peak systolic velocity and high-resistance.
Adult ; Blood Flow Velocity ; Humans ; Lymphangitis/*ultrasonography ; Male ; Penile Diseases/*ultrasonography ; Penis/*blood supply/*ultrasonography ; Ultrasonography, Doppler, Color ; Ultrasonography, Doppler, Pulsed ; Venous Thrombosis/*ultrasonography

BACKGROUND: The precise pathophysiology of venous erectile dysfunction (VED) was still unclear. Dynamic infusion cavernosometry and cavernosography (DICC) was the gold standard approach for the diagnoses of VED. However, a standard operative procedure of DICC was needed and it was unclear whether DICC could show promise in accurate assessment and treatment of VED. The aim of this study was to establish an optimized operation process of DICC and evaluate the efficacy of DICC in the diagnoses and therapy of VED. METHODS: One hundred and forty-seven VED patients identified by the color doppler duplex ultrasonography (CDDU) were included. Then the method of DICC was adopted to assess the severity of VED and all patients were divided into 4 groups, including (1) non-VED; (2) mild VED; (3) moderate VED and (4) severe VED. All patients received the treatment of psychotherapy. Drug therapy, the intervention embolism of corpus cavernosum and the implantation of penile prosthesis were applied if psychotherapy was ineffective for patients. The international index of erectile function (IIEF-5) scores of patients were collected and compared before and after treatment. RESULTS: IIEF-5 score of non-VED group after psychotherapy (19.35 ± 3.59) and drug therapy (23.31 ± 0.75) was higher than that before psychotherapy (15.30 ± 2.72, t = -4.31, P < 0.01) and drug therapy (16.62 ± 1.50, t = -19.13, P < 0.01). IIEF-5 scores of mild VED (18.25 ± 2.60) and moderate VED group (14.83 ± 4.17) after treatment was improved significantly by intervention embolism of corpus cavernosum when compared with those before treatment (mild: 15.50 ± 2.14, t = -2.31, P < 0.05; moderate: 11.83 ± 2.86, t = -1.45, P < 0.05). However, drug therapy and intervention embolism (IE) of corpus cavernosum showed poor effects on patients with moderate and severe VED patients (P > 0.05). IIEF-5 score of severe VED group was increased under the treatment of implantation of penile prosthesis (23.25 ± 0.71) compared with that before treatment (8.00 ± 0.39, t = -53.25, P < 0.05). CONCLUSION DICC was a valid diagnostic tool that could identify patients with VED. And DICC had great effect on the diagnosis and individual therapy for patients with VED in varying degrees. Moreover, the manipulation of DICC needed uniform standards.
Adult ; Embolization, Therapeutic ; Humans ; Impotence, Vasculogenic ; diagnosis ; therapy ; Male ; Middle Aged ; Penis ; blood supply ; diagnostic imaging ; Ultrasonography, Doppler, Color ; Veins

Objective: To investigate the effect and safety of contrast-enhanced ultrasonography (CEUS) in the diagnosis of venous erectile dysfunction (VED). METHODS: From June 2015 to March 2016, 43 ED patients underwent corpus cavernography, of whom 23 were diagnosed with and the other 20 without corpus cavernosal venous leakage (CCVL). All the patients received intracorporal injection of a vasoactive drug and CEUS. RESULTS: Of the 23 patients with CCVL, 21 were confirmed by CEUS, including 12 cases of double venous leakage, 2 cases of single venous leakage, 5 cases of crural venous leakage, and 2 cases of the mixed type, while the other 2 showed no CCVL on CEUS. Of the 20 patients with CCVL, 2 presented CCVL on CEUS. CONCLUSIONS CEUS has the advantages of accuracy, safety, and less invasiveness in the diagnosis of VED.
Contrast Media ; Humans ; Impotence, Vasculogenic ; diagnostic imaging ; Injections ; Male ; Penis ; blood supply ; diagnostic imaging ; Ultrasonography ; methods ; Veins

OBJECTIVETo evaluate deep penile arterial flow after an intracavernosal injection with prostaglandin E1 in patients with erectile dysfunction (ED).

METHODS527 patients with ED were evaluated using Color Doppler Ultrasonography. Diagnostic tests were undertaken after an intracavernosal injection with 20 microg prostaglandin El. The peak systolic velocity (PSV), end diastolic velocity (EDV) and resistive index (RI) were analysed.

RESULTSThere were 112 patients (26.99%) with nonvasculogenic ED, 207 patients (49.88%) with arteriogenic ED, 144 patients (34.70%)with venogenic ED, 64 patients (15.42%)with mixed ED.

CONCLUSIONThe Color Doppler Ultrasonography technique allows accurate location and evaluation of deep penile arteries. Vascular pathology may be differentiated after an intracavernosal injection with a vasomotor agent. Recognising the pathological pattern assists in choosing the best method of treatment.

Adult ; Blood Flow Velocity ; Humans ; Impotence, Vasculogenic ; diagnostic imaging ; physiopathology ; Male ; Middle Aged ; Penis ; blood supply ; diagnostic imaging ; Regional Blood Flow ; Ultrasonography, Doppler, Color

OBJECTIVETo explore the diagnosis and treatment of veno-occlusive priapism.

METHODSThe diagnosis and treatment of 17 cases of veno-occlusive priapism were analyzed retrospectively.

RESULTSAll the 17 patients were evaluated by physical examination, cavernous blood gas analysis and color Doppler ultrasonography, and treated by conservative therapy, intracavernosal aspiration and injection, surgical operation. After treatment, 11 cases achieved complete detumescence, 5 cases partial detumescence and 1 case of penile cancer failed to respond. During the 2-6 months follow-up, erectile dysfunction occurred in 3 cases.

CONCLUSIONCavernous blood gas analysis and color Doppler ultrasonography are helpful to the diagnosis of veno-occlusive priapism. Early and correct intracavernosal injection and corpora cavernosa-corpus spongiosum shunt are effective ways to treat veno-occlusive priapism.

Adult ; Blood Gas Analysis ; Follow-Up Studies ; Humans ; Male ; Middle Aged ; Penis ; blood supply ; Priapism ; diagnostic imaging ; etiology ; therapy ; Retrospective Studies ; Ultrasonography

OBJECTIVETo make a comparative study of duplex ultrasonography (DU) and internal pudendal arteriogram (IPA) in the diagnosis of trauma-associated arteriogenic erectile dysfunction (ED).

METHODSSeven patients suffering from arteriogenic erectile dysfunction caused by pelvic fracture trauma underwent comprehensive history inquiries and physical examinations by duplex ultrasonography and internal pudendal arteriogram, which ruled out neurogenic erectile dysfunction.

RESULTSDU suggested penile artery blood flow injury, and IPA indicated artery injury in all the cases, including left internal pudendal artery injury, right or left common penile artery injury and bilateral common penile artery injury.

CONCLUSIONTrauma-associated arteriogenic erectile dysfunction may result from common penile artery injury and internal pudendal artery injury. DU is proved valuable for evaluating hemodynamic abnormalities of cavernous artery flow, and IPA useful in locating common penile artery and internal pudendal artery injury. DU can be used as the first line diagnostic means to define trauma-associated arteriogenic ED.

Adult ; Angiography ; methods ; Arteries ; diagnostic imaging ; injuries ; Erectile Dysfunction ; diagnostic imaging ; etiology ; Fractures, Bone ; complications ; Humans ; Male ; Pelvic Bones ; injuries ; Penis ; blood supply ; Ultrasonography, Doppler, Duplex ; methods

OBJECTIVE: To determine the diagnostic value of real-time Rigiscan monitoring and Doppler ultrasonography following intracavernous injection of prostaglandin E1in erectile dysfunction(ED). METHODS: From January 1998 to December 2007, 1 392 ED patients completed the test. PGE(1) was injected into corpus cavernosum penis near the radix penis with injection guns. After 1 or 2 minutes, the Rigiscan Plus device was used for real-time evaluation of penile rigidity. Optimal injected dosage of each patient with positive reaction was determined. Injected dosage of patients with negative reaction was gradually increased from to 60 microg. As the dosage was established, color Doppler ultrasonography was used to assess the morphodynamic features of cavernosal arteries. RESULTS: Altogether 1 039 patients were positive, while 353 patients were negative by Rigiscan. In the 1 039 positive patients,663 were injected with 10 microg PGE(1), 265 patients 20 microg, 97 patients 30 microg,and 14 patients 60 microg while 89(13.4%),39(14.7%),41(42.3%),and 10(71.4%) patients were diagnosed vascular ED. Of the 353 negative patients, 267(75.64%) patients were diagnosed vascular ED. During intracavernous pharmacological testing,the more PGE(1) was used, the more vascular ED patients would be found(P<0.001). CONCLUSION PGE(1) is safe and effective for the erectile responses. The dosage of PGE(1) following intracavernous injection is related to vascular ED. Real-time Rigiscan monitoring combined with color Doppler ultrasonograph can be helpful to diagnose penile vascular diseases.
Adult ; Alprostadil ; administration & dosage ; Erectile Dysfunction ; diagnosis ; diagnostic imaging ; physiopathology ; Humans ; Male ; Penile Erection ; Penis ; blood supply ; diagnostic imaging ; Ultrasonography, Doppler, Color

OBJECTIVETo explore an efficacious therapy for arterial erectile dysfunction (ED) by observing the effect of the Chinese traditional medicine Zhenyangjian on the penile hemodynamics of the patient.

METHODSForty-seven patients with arterial ED, aged from 40 to 49 years, were treated with Zhenyangjian for 1 month. Intracavernous injection of papaverine and phentolamine (30 mg/l mg) was given and multifunctional color Doppler ultrasound was used to measure the peak systolic velocity(PSV) of the corpus cavernous arteries before and after Zhenyangjian administration.

RESULTSThe PSV of the penis corpus cavernous arteries was obviously ameliorated in all the patients (P < 0.05).

CONCLUSIONThe Chinese traditional medicine Zhenyangjian can promote penile erection effectively.

Adult ; Drugs, Chinese Herbal ; therapeutic use ; Humans ; Impotence, Vasculogenic ; drug therapy ; physiopathology ; Male ; Middle Aged ; Penis ; blood supply ; diagnostic imaging ; Phytotherapy ; Regional Blood Flow ; drug effects ; physiology ; Ultrasonography, Doppler, Color

AIMErectile dysfunction may be observed in up to 80% of patients with Peyronie's disease. An objective evaluation of the erectile function is attempted to work out in patients with Peyronie's disease.

METHODSPenile deformity, sexual function and penile vascular status were analyzed in 123 patients with Peyronie's disease, who had not received any pertinent treatment.

RESULTSPenile deformity, palpable plaque and pain on erection were seen in 112 (91%), 97 (78.8%) and 27 (21.9%) of the 123 patients, respectively. Of the 76 patients evaluated by color Doppler ultrasounography, veno-occlusive dysfunction as the vascular component for erectile dysfunction was found in 17 (22.3%), arterial insufficiency in 10 (13.1%) and a mixed picture in 23 (30.2%).

CONCLUSIONThe documentation of penile erectile function and the determination of the vascular status using color Doppler ultrasonography can guide the appropriate therapeutic choice.

Adult ; Aged ; Antioxidants ; therapeutic use ; Colchicine ; therapeutic use ; Erectile Dysfunction ; diagnostic imaging ; drug therapy ; physiopathology ; Gout Suppressants ; therapeutic use ; Humans ; Male ; Middle Aged ; Penile Induration ; diagnostic imaging ; drug therapy ; physiopathology ; Penis ; blood supply ; pathology ; physiopathology ; Ultrasonography, Doppler, Color ; Vitamin E ; therapeutic use