275 penile cancers were recorded for history of phymosis. Among these, 92.4% are without this history. However, the delay in circumcision related to risk of penile cancer later. The rate of advanced penile cancer in patients with history of phymosis is higher than that of patients without this history. Therefore, it is important to educate on circumcision for the children with phymosis before they gain puberty.
Penile Neoplasms ; Neoplasms

The incidence of Giant Condyloma Acuminata of the penis is unknown but considered rare. They are similar to condyloma acuminata, histologically and grossly similar to squamous cell ca. Most authorists consider that they get the real possibility of malignant change and they had been first described by Buschke in the German literatures in l896 as a variant of condyloma acuminata. A case of malignancy of the penis which has apparently transformed from Giant Condyloma Acuminata of the penis is herein presented with review of related literatures.
Incidence ; Male ; Penile Neoplasms* ; Penis

PURPOSE: Cavernosal smooth-muscle relaxation is essential for penile erection Reduction or dysfunction of the muscle fibers can be related to impaired relaxation of cavernosal smooth muscle. Our study was aimed at seeing the changes in penile smooth muscle and collagen tissue in patients with erectile dysfunction. PATIENTS AND METHODS: Twelve impotent patients (study group; mean age 56.3 years) and five penile cancer patients (control group; mean age 57.6 years) were included. The cause of the impotence was Peyronie's disease, diabetes, and unknown in four patients each. Cavernosal tissues were obtained at the time of penile prosthesis implantation and fixed immediately in 10% Formalin. After staining with Masson's trichrome, analysis of smooth muscle fibers was performed using ImagePro. RESULTS: The smooth muscle ratio was 75.1+/-8.19% (SD) in the control group, 37.7+/-12.2 in Peyronie's disease, 37.1+/-18.4% in the patients with diabetes, and 52.2+/-10.6% in the group with no known underlying disease. There was a statistically significant difference in the smooth muscle ratio between the study and control group, but among the study groups, no significant difference was noted. CONCLUSIONS: Altered content of smooth muscle may contribute to the pathophysiology of erectile dysfunction.
Collagen* ; Erectile Dysfunction* ; Formaldehyde ; Humans ; Male ; Muscle, Smooth* ; Penile Erection ; Penile Implantation ; Penile Induration ; Penile Neoplasms ; Penis ; Relaxation

Malignant melanomas of the genitourinary tract are uncommon, accounting for less than 1% of all cases of melanoma and only a small percentage of penile carcinoma. In industrialized counties, penile cancer is an uncommon malignancy, with a reported annual incidence of 1 per 100,000 men. Malignant melanoma of the penis is a rare lesion and will be encountered infrequently during urological practice. Here in, we report a case of primary malignant melanoma of the penis and a brief review of the literature.
Humans ; Incidence ; Male ; Melanoma* ; Penile Neoplasms ; Penis*

PURPOSE: Due to the increasing numbers of radical prostatectomies (RP) performed for prostate cancer, a substantial and increasing number of patients suffer from postoperative urinary incontinence and erectile dysfunction (ED). The objective of our study was to see whether an inflatable penile prosthesis implantation could control urinary incontinence for patients with the dual problems of ED and incontinence. MATERIALS AND METHODS: From March 2010 through May 2015, 25 post-RP patients were referred to our clinic with ED or incontinence. The degree of incontinence was classified according to the International Consultation on Incontinence Questionnaire-Short Form. Inflatable penile prostheses were implanted in all 25 patients. RESULTS: For one month after implantation, partial or full inflation was performed progressively to control urine leakage. Of 18 patients, 13 patients were categorized with mild or moderate stress incontinence. All 13 patients obtained control of incontinence with partial inflation (30% to 60%) and all reported satisfactory outcomes. Five out of the 18 patients were categorized with severe total incontinence. Three of the 5 patients could tolerate incontinence with full inflation on and off. Thirteen patients out of the total of 18 (72.2%) had their incontinence controlled by an inflating penile prosthesis. CONCLUSIONS: An inflatable penile prosthesis is highly recommended as an initial procedure, especially in patients with the dual problems of ED and incontinence.
Erectile Dysfunction ; Humans ; Inflation, Economic ; Male ; Penile Implantation ; Penile Prosthesis* ; Prostatectomy ; Prostatic Neoplasms ; Urinary Incontinence*

Treatment options for clinically localized prostate cancer include surgical extirpation, radiation therapy(external beam radiation therapy and/or brachytherapy), or watchful waiting. Cryosurgery has recently re-emerged as a developing technology and as a minimally invasive treatment option. There may be technical difficulties in placing cryoprobes in patient with a penile prosthesis. To the best of our knowledge, this is the first report of cryosurgical ablation of the prostate in a prostate cancer patient with a penile prosthesis.
Cryosurgery* ; Cryotherapy ; Humans ; Penile Prosthesis* ; Prostate* ; Prostatic Neoplasms* ; Watchful Waiting

The condition of pseudo-epitheliomatous keratotic and micaceous balanitis (PKMB) has been described as a rare, scaling, raised lesion of the glans penis, which on histological examination showed acanthosis, hyperkeratosis and pseudo-epitheliomatous hyperplasia. It was originally thought to be a benign condition. However, recent case reports suggest that PKMB has a high propensity for malignant change. Treatment by biopsy has shown that pseudo-epitheliomatous keratotic and micaceous balanitis should be determined by the severity of the disease. We report a case of PKMB in a 38-year-old man, who presented with a one year history of an eruption on the glans penis.
Adult ; Balanitis* ; Biopsy ; Humans ; Hyperplasia ; Male ; Penile Neoplasms ; Penis

We used the method of partial penectomy combined with penis lengthening to treat 2 cases of penile cancer. The penile lengths were lengthened by 3-4 cm. This method could retain the penis and sexual function to the maximum degree. And a few patients could avoid total penectomy and micturate on their feet. This operation is very simple and safe, with no complication.
Aged ; Humans ; Male ; Middle Aged ; Penile Neoplasms ; surgery ; Penis ; surgery

Human papillomavirus (HPV) infection is one of the major risk factors for penile cancer. This article presents an overview on the biological characteristics of HPVs, HPV infection in penile cancer, possible carcinogenic mechanisms of HPV, prognostic value of HPV in penile cancer, and HPV vaccine.
Humans ; Male ; Papillomaviridae ; Papillomavirus Infections ; Penile Neoplasms ; virology

Penile metastases are rare, and usually secondary to other genitourinary primary tumors. Bladder, prostate and renal tumors are the main sources of penile metastasis. Rectal and respiratory neoplasms also metastasize to the penis. However, metastatic penile cancer originating from the pancreas is extremely rare. Here, a case of pancreatic cancer, with penile metastasis, is reported.
Male ; Neoplasm Metastasis ; Pancreas* ; Pancreatic Neoplasms ; Penile Neoplasms* ; Penis ; Prostate ; Urinary Bladder