OBJECTIVE: To explore the relationship among loneliness at workplace, job burnout, and turnover intention in prison policemen. METHODS: A convenience sampling method was used to select a total of 290 prison policemen officers as the study subjects in Guangxi Zhuang Autonomous Region. The Workplace Loneliness Scale, Job Burnout Scale and Turnover Intention Scale were used to investigate the loneliness at workplace, job burnout and turnover intention respectively.RESULTS: The scores of turnover intention of 31-40 age group were higher than that of 41 or over age group(P<0.01). The scores of turnover intention in the length of service 1-5 years group and 6-10 year length of service group were higher than that of length of service over 16 years or more(P<0.05). The scores of turnover intention of section group policemen were higher than that of division group(P<0.05). The loneliness in the workplace was positively correlated with job burnout[Spearman rank correlation coefficient(r_S)=0.343, P<0.01], and turnover intention(r_S=0.392, P<0.01), and job burnout was positively correlated with turnover intention(r_S=0.408, P<0.01). Job burnout was the intermediate variable between loneliness in the workplace and turnover intention with a mediating effect rate of 60.2%. CONCLUSION: The job burnout of prison policemen plays a partial role in mediating the influence of loneliness at workplace on turnover intention.