1.Garden Burnet Embolism in the Treatment of the Fibroid Clinical Observation
Pengtian ZHANG ; Mairong WANG ; Zhaoguo ZHANG
Journal of Zhejiang Chinese Medical University 2006;0(05):-
[Objective] Discuss traditional Chinese medicine garden burnet powder embolism treating fibroid's action mechanism.[Methods] Treat 120 patients with line of ultra selective arteria uterina intubation radiography and embolism,observe result after 3~12 months,make a follow-up visit.[Results] Arteria uterina radiography demonstrats fibroid for rich vascular tumor;after TUAE treatment,treatment group 84.31%,control group 83.33%;the patient menstrual volume restores normally gradually;at 2 month reexamination,treatment group 80.95%,control group 77.5%;the patient hemoglobin value achieves the normal level.At follow-up visit,the myoma size of the treatment group is reduced to an average of 73.2%,the control group reduced to 70.1%.[Conclusion] The garden burnet powder involving embolism treating the fibroid has the superiority and the security compared to other material,opening one new way,having the important clinical practice value,worth clinical further consummating and promoting.
2.Efficacy observation of glutathione on prevention of acute radiation enteritis in pelvic radiation therapy
Zhenchao MA ; Zhenxin ZHOU ; Haibing ZHANG ; Pengtian JI ; Genhua YU
Chinese Journal of Primary Medicine and Pharmacy 2016;23(20):3151-3154
Objective To observe the prevention effect of glutathione on acute radiation enteritis in pelvic radiation therapy.Methods All 80 pelvic tumor patients treated with radiotherapy were randomly assigned to the control group (40 patients)and the treatment group (40 patients)by the number table method.40 cases in the con-trol group treated with radiation were not treated with preventive drugs,but the patients in the treatment group were treated with glutathione.The occurrence time of acute radiation enteritis and the severity of acute radiation enteritis after treatment were evaluated.Results 15.0% of the treatment group suffered from acute radiation enteritis in the second week and 72.5% in the third week.however,62.5% of the control group were suffered from acute radiation enteritis in the second week and 27.5% in the third week.The difference was statistically significant (χ2 =18.775, 15.998,all P <0.001).Glutathione delayed the occurrence time of acute radiation enteritis.The grade 1 and grade 2 acute radiation enteritis effective rate in the treatment group were 77.5% and 17.5%,and that in the control group were 20.0% and 72.5%,the difference between the two groups was significant(χ2 =26.136,24.139,all P <0.001).The glutathione could reduce the incidence of acute radiation enteritis extent.Conclusion Glutathione could delay the occurrence time of acute radiation enteritis and reduce the incidence of acute radiation enteritis extent.It is worth clinical application.
3.Risk factors of nosocomial infections in patients with head and neck cancer during radiotherapy
Haibing ZHANG ; Jianwei XU ; Shaojun ZHENG ; Lixin RU ; Genhua YU ; Pengtian JI
Chinese Journal of Clinical Infectious Diseases 2016;(1):32-36
Objective To investigate the risk factors of nosocomial infections in patients with head and neck cancer during radiotherapy .Methods Clinical data of 189 patients with head and neck cancer receiving radiotherapy in Huzhou Central Hospital during August 2011 and December 2014 were retrospectively studied .Chi-square test and multivariate Logistic regression analysis were performed to explore the risk factors of nosocomial infections in patients during radiotherapy .Results Among 189 patients with head and neck cancer receiving radiotherapy , nosocomial infection was observed in 64 (33.86%) patients.Univariate analysis showed that radiation-induced oral mucositis (χ2 =11.47, P<0.01), underlying disease (χ2 =6.59, P<0.05), stage of tumor Ⅲ-Ⅳ (χ2 =4.36, P<0.05), whole-neck radiation (χ2 =7.64, P <0.05), dose of radiation ≥50 Gy(χ2 =8.92, P <0.05), combined chemotherapy (χ2 =6.53, P<0.01), invasive operation (χ2 =4.21, P<0.05), PS score=1 (χ2 =3.58, P<0.05) and low body mass index (χ2 =9.56, P <0.05) were risk factors of nosocomial infections . Multivariate Logistic regression analysis indicated that radiation-induced oral mucositis ( OR=3.46, χ2 =8.72, P<0.01),underlying disease (OR=1.91, χ2 =4.66, P<0.05), stage of tumor Ⅲ-Ⅳ (OR=2.01,χ2 =5.22, P<0.05), whole-neck radiation (OR=1.78,χ2 =4.89, P<0.05), dose of radiation ≥50 Gy (OR=1.69,χ2 =3.25, P<0.05), combined chemotherapy (OR=1.84, χ2 =6.91, P<0.05) and low body mass index (OR=1.53, χ2 =2.59, P<0.05) were independent risk factors of nosocomial infection.Conclusions Nosocomial infections are popular in patients with head and neck cancer during radiotherapy.Radiation-induced oral mucositis, underlying disease, stage of tumor, radiation field, dose of radiation, combined chemotherapy and body mass index are associated with the occurrence of nosocomial infections in these patients .