1.Research on the Development of Translation Disambiguation Technology in Cross - language Information Retrieval
Journal of Medical Informatics 2009;30(7):1-5
The paper introduces the connotation and development of cross - language information retrieval (CLIR), furthermore, ten kinds of translation disambiguation techniques are demonstrated as following. In addition it carries out contrastive analysis and expla-nation of disambiguation from four aspects, including core foundation, application status, potential improvement and development pros-pects. On this base it summarizes the status and development trends and proposes several directions of future research.
2.The status and progress of relationship between macrophages polarization and choroidal neovascularization
Chinese Journal of Ocular Fundus Diseases 2016;32(1):96-99
Macrophages are major effecter cells of nonspecific immune response,the polarization of which plays a great role in inflammation,repairing and angiogenesis.According to functional phenotypes,macrophages can be polarized to classically activated type (M1),which could promote angiogenesis,and alternatively activated type (M2),which could inhibit angiogenesis.The proportion of M1/M2 could modulate the growth of choroidal neovascularization (CNV).Under the conditions of aging and injury within the retina,macrophages may polarize to M2,which could generate several proangiogenic factors,initiating and promoting the formation of angiogenesis and fibrous scar.Therefore,regulation of macrophage polarization is expected to inhibit angiogenesis and provide new insight for treatment of CNV.
3.Application of attenuated salmonella in the gene treatment of tumor
Journal of International Oncology 2013;40(10):748-751
Salmonella is a kind of intracellular invasive facultative anaerobe,maintaining its antigenicity after being attenuated.Now,it has been widely used as a transporter of DNA vaccines.Salmonella carrying related antigen gene can inhibit multiple tumors,and salmonella carrying repair gene has a clear repair effect for the organism injury after chemoradiotherapy.
4.Imaging Diagnosis of Primary Spinal Tumors
Journal of Practical Radiology 2001;0(09):-
Objective To anlayze the imaging diagnosis of spinal primary tumor.Methods Fifty and nine cases of spinal primary tumors confirmed by pathology were analyzed retrospectively.Results Of 59 cases,there were chordoma in 23,hemangioma in 7,giant cell tumor of bone in 11,aneurysmal bone cyst in 5,osteoblastoma in 7,osteogenous sarcoma in 2,myeloma in 2,spinal eosinophilic granuloma in 1 and primary bone lymphoma in 1.These tumors had its own imaging characteristics.Conclusion Imaging examinations are of significant value for the clinical treatment of spinal primary bone tumor.
5.A study on ego identity and mental health of students in athletes and their relationship
Yuanbing GUO ; Chaoyun HUANG ; Pengfei SUN
Chinese Journal of Behavioral Medicine and Brain Science 2008;17(11):1031-1033
Objective To study the ego identity,mental health and their relationship among students in athletes.Methods 110 students in athletes and 122 athletes in students were measured with identity status scale and athletes' symptom checklist.Results ①Students in athletes have higher "present serf-commitment" (5.09±1.07)and lower "crisis in the past"(2.19±1.12)than athletes in students.The two demonstrate the obvious difference on the distribution of identity status.The percentage of students in athletes obtaining A is lower than that of athletes in students ,while the percentage of students in athletes obtaining D and MD is higher. ②Comparing with the norm,students in athletes have higher level on the factors of sematizafion (1.98±0.42),compulsion (2.21±0.51),interpersonal sensitivity(2.09±0.53),depression (1.85±0.53),anxiety ( 2.47 ~0.58 ),paranoid (1.98±0.21),psychoticism (1.79±0.22) and total average marks (2.00±0.34),lower level on the factors of hostility (1.43±0.48)and cognitive(1.64±0.31). ③Three domains of ego identity exit obvious negative correlation with the sores of psychological symptoms.ANOVA confined that the more advanced ego identity is,the better mental health is.Conclusion Ego identity and mental health of students in athletes have their own features,and ego i-dentity will influence mental health.
6.The clinical value of 3-dimensional DSA in the diagnosis of intracranial aneurysms
Xiaodong KANG ; Pengfei SUN ; Wuquan WANG
Journal of Practical Radiology 2014;(8):1271-1274
Objective To explore the clinical value of 3-dimensional digital subtraction angiography(3D-DSA)in the diagnosis and therapy of intracranial aneurysms.Methods 2-dimensional digital subtraction angiography (2D-DSA)and 3D-DSA was performed respectively on 1 53 patients,including 1 5 1 cases with spontaneous subarachnoid hemorrhage (SAH),1 case with headache and 1 case with cerebral infarction;Meanwhile,to compare the difference in diagnosis of intracranial aneurysms between 2D-DSA and 3D-DSA.Results 1 12 patients(125 pieces)with intracranial aneurysms were detected on 2D-DSA,its detecting rate was 73.2%(1 12/1 53 );136 patients(1 52 pieces)with intracranial aneurysms were detected on 3D-DSA,its detecting rate was 88.9%(136/1 53)(χ2 =12.254,P <0.05).The displaying rate of 3D-DSA for the relationship between carrying tumor artery and aneurysms and the necks of aneurysms was 100%(1 52/1 52),however,the displaying rate of 2D-DSA for that was 61.6%(77/125)(χ2 =63.993,P <0.05). Conclusion 3D-DSA can improved the diagnostic accurate rate of intracranial aneurysms,it is important in chosing the therapeutic regimen.
7.Experimental Study of Huangqikeli on Immune Function of Mice
Pengfei XU ; Jinghui SUN ; Fuyun GAO
Chinese Journal of Information on Traditional Chinese Medicine 2006;0(04):-
Objective To investigate the effect of Huangqikeli on immune function of mice. Methods 30 mice were randomly divided into 3 groups. The mice in A and B group were administrated with distilled water,C group were administrated with Huangqikeli. On the tenth day,all groups except A group were injected with cyclophosphamide to induce the model. The effects on the phagocytic function of Huangqikeli to macrophage in abdominal cavity of mice,delayed hypersensitivity induced by DNCB,and production of hemolysin antibody in mice that CRBC sensitized were observed. Result Compared with immuno-suppressive models given distilled water (B group),phagocytic function of macrophage in abdominal cavity of mice and delay hypersensitivity leaded by DNCB were enhanced (P
8.Influence of Yudan Rongxin Keli on Immunoregulation in Mice
Pengfei XU ; Jinghui SUN ; Fuyun GAO
Chinese Journal of Information on Traditional Chinese Medicine 2006;0(02):-
Objective To investigate the influence of Yudan Rongxin Keli on immunoregulation in mice. Methods The mice were randomly divided into the normal group, cyclophosphamide (Cy) model group, Yudan Rongxin Pill group and Yudan Rongxin Keli group. The effects of Yudan Rongxin Keli on the phagocytosis of macrophage in mouse abdomen, delayed-type hypersensitivity (DTH) induced by dinitrochlorobenzene (NDCB), and generation of hemolysin antibody induced by chicken red blood cell (CRBC) were observed respectively. Result Compare with the Cy model group, the phagocytosis of macrophage in Yudan Rongxin Keli group was promoted (P
9.Integrin ?2 and ?3 expression and its clinical value in bladder transitional cell carcinoma
Fanghu SUN ; Pengfei SHEN ; Jiangbo HUANG
Chinese Journal of Urology 2001;0(11):-
50%).RT-PCR results were classified as positive and negative according to the presence or absence of corresponding electrophoretic bands. Results Immunohistochemically,integrin ?2 and ?3 subunits were all expressed strongly in 12 cases of normal bladder tissues (100%).In 53 cases of BTCC tissues,?2 was strongly positive in 10 cases (19%),positive in 22(42%),negative in 21(40%);?3 was strongly positive in 16 (30%),positive in 24 (45%),negative in 13(25%).The expressions of ?2 and ?3 were significantly different between normal and BTCC tissues ( P 0.05).RT-PCR results showed that ?3 expression was positive in all normal tissues (100%) and in 36 (68%) out of the 53 cases of BTCC tissues;the difference was significant ( P 0.05),but ?3 mRNA positive expression was significantly related to clinical stages [T is ~T 1:83%(19/23),T 2~T 4:57%(17/30); P
10.Titanium specimens with different surface character affect the proliferation and IL-6 and Cbfα1 expres-sion in osteoblasts
Pengfei XUE ; Yudong HOU ; Jingjing PAN ; Long SUN ; Xin SUN
Journal of Practical Stomatology 2015;(3):335-338
Objective:To investigate the effects of titanium spcimens with different surface character on the proliferation and mRNA expression of IL-6 and Cbfα1 in osteoblasts.Methods:Titanium surface was treated by smooth pretreatment(PT),sandblast and acid etch(SLA)and anodic oxidation(AD)respectively.The morphology and the elements analysis of the spcimens were inspected and detected by SEMand EDS.The surface contact angle was measured by contact angle meter.MC3T3-E1 cells were cultured on the titanium surface and cells cultured on tissue culture plate were served as the control group.The proliferation was measured by MTT assay.The mRNA expression of IL-6 and Cbfα1 was quantified by RT-qPCR.Results:The sample surface in PT group showed scrat-ches,in SLA group showed multiple three dimensional structure,in AD group exhibited porous structure.The elements of the sample surface of group PT,SLA and AD were Ti,Ti/Al and Ti/O respectively;the contact angles were 54.47°±3.33°,75.42°±8.32° and 38.91 °±4.00°respectively(P<0.05).The cells in AD group showed higher proliferation than those in PT and SLA groups(P<0.05).In AD group IL-6 mRNA expression decreased and Cbfα1 mRNA increased more than in PT and SLA groups(P<0.05). Conclusion:Titanium spcimens treated with AD may promote cell proliferation,decrease IL-6 mRNA expression and increase Cbfα1 mRNA expression in MC3T3 cells.Implats treated with AD might have some advantages in early osseointegration.