Objective: Introduce Internet and wireless communication technology into radiology image remote diagnosis system, develop a new system combined with PACS. Material and Methods: Used ASP.NET technology under VS. NET2005, and used JAVA to develop the image APPLET, Web server used 11S5.0, database used Microsoft SQL Server. Also need a SMS Modern to send message online. Results: Offer two ways to access medical image remote diagnosis system: Interact and wireless networks. Wherever a doctor he is, as long as has a computer or mobile phones can be connected to Interact or wireless network, can login diagnosis system, browse the patients' images, do some image processing, and also can send reports. Conclusions: The system can be put into practice, lifting the restrictions in time and place of remote diagnosis system, it try in full-development of telemedicine. Although at present reports of this form does not have legal effectiveness, this paper provided a new idea for development of medical image remote diagnosis system.

ObjectiveTo reduce the effective dose and maintain the image quality by adjusting the image processing parameters in the lumbar spine examinations.Methods This study investigated the influence of image processing parameters on image quality of Philips DR system by evaluating image quality of CDRAD 2.0 phantom.The parameters include detail contrast enhancement,noise compensation,unsharp masking and unsharp masking kernel.The entrance surface dose of phantom was measured by solidose meter.A synthetical parameters optimization project was proposed by analyzing the results of the investigation.This project was also testified by phantoms.ResultsImportant effects were the main effects of DCE,unsharp masking and kernel at the clinically used tube potential of 70 kVp( F =91.45,373.79,429.88,P ＜ 0.05).These effects indicated an increase of the 1QF about 20 units with increasing unsharp masking,while an increase of DCE and kernel led to decrease of IQF about 10 and 21 units.When the tube potential was increased to 85 kV,keeping the settings of the process parameters unchanged,the IQF increased.The results showed statically significant difference ( t =5.31,P ＜ 0.05 ).ConclusionIt is possible to lower the effective dose to the patient by the use of a higher tube potential and maintain a good image quality,and it will have little influence on clinic diagnosis through the most optimal setting of the process parameters.

Objective The imaging quality and irradiation dose were compared between scatter filtering template performance and conventional grid in digital radiography.MethodsImages of contrast-detail phantom and ROC statistic phantom corrected with scatter filtering template method and grid were obtained,respectively.The image quality factors(IQF)and sihnal detection probability values(Pdet)and imaging dose were analyzed by ANOVA,SNK and t test statistics for the two methods of scatter removing.ResultsThe difference of IQF and signal detection probability of images corrected by scatter filtering template technique and conventional snd Was statistically significant.ConclusionsIn digital radiography,STFF can effectively filter scattering,improve image quality without increasing the exposure.With the same image quality.it can reduce the entrance surface dose by about 30% than filter grid.In order to effectively filter scattering,improve the quality of X-ray image,and reduce the patient dose.STFF is an alternative method.

Objective To study the effects of paeonol on the tyrosinase activity and melanogenesis in co-culture model of human melanocytes and keratinocytes. Methods Melanocytes and the co-culture model of human melanocytes and keratinocytes were cultivated and the proliferation of melanocytes and the co-cultures was measured by MTT colorimetric assay. The tyrosinase activity and melanin level were measured by enzymic method. Results The melanin synthesis and tyrosinase activity were markedly suppressed by paeonol in a dose-dependent manner at the concentrations of 50?mol/L, 100?mol/L, and 200?mol/L in both melanocytes and co-cultures. The significant stronger suppression was observed with 100?mol/L and 200?mol/L of paeonol than that with controls (P

Aim To determine the plasma protein binding rate of five components of Eucommia ulmoides extract. Methods The equilibrium dialysis method was used to study the plasma protein binding rate. The plasma samples were extracted by protein precipitation with methanol. With the use of puerarin as the internal standard, UPLC-MS/MS was carried out to determine the concentration of the five compounds in and out of the dialysis membrane. Results The average plasma protein binding rates of five compounds on the area of the concentration which was determinate were as fol-lows, respectively: geniposidic acid was ( 25. 77 ± 2. 68 )%, protocatechuic acid was ( 57. 54 ± 3. 79)%, chlorogenic acid was (53. 91 ± 3. 00)%, pinoresinol diglucoside was (24. 15 ± 4. 92)%, and pinoresinol singleglucoside was (49. 78 ± 3. 61)%. Conclusions The results show that the binding percentage of geniposidic acid and pinoresinol diglucoside is relatively low, but the binding rate of the others with rat plasma protein is moderate.

Tissue engineering technology provides a new method to repair ill tissue and worn-out organs. In tissue engineering, scaffolds play an important role in supporting cell growth, inducing tissue regeneration, controlling tissue structure and releasing active factor. In the last decade, electrospinning technology developed rapidly and opened vast application fields for scaffolds. In this review, we summarized the technological conditions of electrospinning for scaffolds, the study of electrospun fiber scaffolds applied in tissue cell cultivation, and some new directions of electrospinning technology for scaffolds. We also addressed development directions of electrospinning research for scaffolds.
Absorbable Implants ; Biocompatible Materials ; chemistry ; Electrochemistry ; methods ; Guided Tissue Regeneration ; Tissue Engineering ; instrumentation ; methods ; Tissue Scaffolds ; chemistry

Objective To investigate the variation characteristics of peripheral platelet parameters in children with dengue fever and to assess their use and value in diagnosis,prognosis and treatment for dengue fever.Methods Platelet parameters of 69 pediatric patients with dengue fever in acute febrile phase and remission period and 103 healthy controls were compared.The difference of platelet parameters between the liver function injury group and the normal liver function group,the coagulation dysfunction group and the coagulation function normal group,the severe group and the mild group with dengue fever was compared,the causes of thrombocytopenia in children with dengue was investigated so as to better understand the situation of bone marrow producing platelets.Results P-LCR,PDW,MPV were significantly higher in patients in acute febrile phase of dengue fever,compared with the healthy subjects(P＜0.01),while PCT,PLT were significantly lower in patients in acute febrile phase of dengue fever,compared with the healthy subjects(P＜0.01).MPV was significantly lower in patients with abnormal hepatic function when compared with patients with normal hepatic function(P＜0.05),while other platelet parameters did not show significant differences(P＞0.05).PLT and PCT were significantly lower in the severe patients than those in the mild patients(P＜0.05),while other platelet parameters did not show significant differences(P＞0.05).Peripheral platelet parameters did not show significant differences between patients with or without abnormal coagulation function (P＞0.05).Conclusion Peripheral platelet parameters may play a role in the diagnosis,treatment and prognosis of dengue fever in children.

BACKGROUNDThoracic endovascular aortic repair (TEVAR) is an emerging treatment modality, which has been rapidly embraced by clinicians treating thoracic aortic disease. However, the clinical manifestations of systemic inflammatory response after TEVAR as post-implantation syndrome (PIS) resemble the perioperative infection. This study aimed to evaluate changes and diagnostic value of procalcitonin (PCT) and other traditional inflammatory markers for infections after TEVAR.

METHODSWe conducted a prospective clinical study that enrolled 162 consecutive aortic dissection cases, who underwent TEVAR in our institution between July 2011 and November 2012. The PCT, C-response protein (CRP), erythrocyte sedimentation rate (ESR) and blood routine examination were monitored before the operation and on days 1, 2, 3 and 5 after the operation. The diagnosis of infection was confirmed by the infection control committee with reference to Hospital Acquired Infection Diagnostic Criteria Assessment, released by the Ministry of Health of the People's Republic of China.

RESULTSPost endovascular repair of thoracic aorta, PCT changes significantly at different time points (χ(2) = 13.225, P = 0.021), without significant difference between the PIS group and the control group (0.24 ± 0.04 vs.0.26 ± 0.10, P = 0.804). PCT values were significantly higher in the first day after TEVAR than the preoperative levels (0.18 ± 0.03 vs. 0.11 ± 0.02, P < 0.001). Compared with PIS patients, the level of PCT, CRP, White blood cell (WBC) and neutrophil (NEU) in the infection patients elevated significantly (relatively χ(2) = 6.062, P = 0.048; χ(2) = 6.081, P = 0.048; χ(2) = 11.030, P = 0.004; χ(2) = 14.632, P = 0.001). According to the ROC analysis, the PCT levels in the first day after TEVAR (AUC = 0.785, P = 0.012) had better predictive values of infection than WBC, NEU CRP and ESR (AUC = 0.720, P = 0.040; AUC = 0.715, P = 0.045; AUC = 0.663, P = 0.274; AUC = 0.502, P = 0.991). The best predictive index was the changes of PCT between preoperative and postoperative (PCT), which possess AUC as 0.803 (P = 0.014). And PCT = 0.055 could be considered as an infection diagnosis cutoff value with a sensitivity of 83.3% and specificity 69.0%.

CONCLUSIONSPCT provides better diagnostic value of infection compared with other inflammatory markers. The potential applications of PCT in differential diagnosis of PIS and infection after percutaneous TEVAR deserve further studies.

Adult ; Aged ; Blood Sedimentation ; C-Reactive Protein ; metabolism ; Calcitonin ; metabolism ; Calcitonin Gene-Related Peptide ; Diagnosis, Differential ; Female ; Humans ; Male ; Middle Aged ; Prospective Studies ; Protein Precursors ; metabolism ; Vascular Surgical Procedures