In order to effectively and smoothly conduct an assessment of students' study in medical physics,it is necessary to design the assessment criteria for enhancing students' development in medical physics study.This paper deals with the construction of the assessment system and the design of the assessment criteria for evaluating students' study in the education of medical physics.

Objective To evaluate the CT values in diagnosis of renal tuberculosis. Methods 26 cases were collected , the CT findings of renal tuberculosis were analysed and compared with the data of operation-pathology and clinical followed up. Results Of 26 cases, 22 cases diagnosed by CT as renal tuberculosis of one side were confirmed by operation-pathology but one (pseudaneurysm). Bilateral renal tuberculosis and renal cysts were diagnosed in 2 cases respectively by CT, while these 4 cases were confirmed as tuberculosis by other auxiliary checking methods and followed-up. The multiple tuberculoses cavities appeared as a petal-shape low-density area and other untypical signs on CT. The single cavity only showed as a low-density area should be distinguished with cystonephrosis. At early renal tuberculosis, a great quantity of effusion beneath the perinephrium was the only sign on CT.Conclusion CT scan has a special value for diagnosis renal tuberculosis. Typical renal tuberculosis can be made closely combining with the clinical information.

0.05) but quite different from European and African's(P

The first part of the work consists of thiamine analysis of 5 allotments of rice samples bought from retail shops in various districts in Canton from the end of 1954 to the beginning of 1957. Usually seven grades of rice are available, and the grades differ both in variety and extraction rate.It is found that the thiamine content of rice bought at the same time, or of the same grade bought within a few months may vary considerably. Two-third of the samples contain 0.11 to 0.18 mg of thiamine per 100 g of rice but it takes the range of 0.05 to 0.27 mg per 100 g to cover all the samples. With the exception of the lowest grade, the thiamine content in general increases with the lowering of grade and decrease of price.The second part of the work studies the influence of variety and of extraction rate upon the thiamine, niacin, riboflavin and protein content of rice. Seven varieties of rice commonly used for the seven grades extracted at different rates are obtained from a local rice mill by special arrangement with the City Food Bureau. 'Results show that milling decreases the content of these 3 vitamins and of protein, the decrease for thiamine and niacin being greater than for the other two nutrients. However, not only the original content of these nutrients in husked rice may vary, but also their degree of loss in milling may differ. Of the varieties studied the lowest grade of husked rice contains the greatest amounts of all the four nutrients while the "Super Grade A" tends to lose the least during milling. As a result, the milled products of these two varieties tend to contain slightly larger quantities of these nutrients.

This paper deals with the program for the course content concordance of medical physics for the five-year medical students based on the course theory,in combination with the practical condition of the medical college,and by means of the study of course theory,course objectives and the textbook.

How to select and organize the content of course is an important component in curriculum reform. The special part for medicine in medical physics has characteristics of medical college, and is essential. The integration of this part is difficulty in curriculum reform of medical physics. In detail, the corresponding part of physics for medicine is integrated into a topic, which followed the part of classical physics. We adopted the method of special-topic teaching. Based on teaching experiences and in combination with the practical condition of the medical college, this paper selects and recombines some course content for medicine from medical physics, which is adopted by five-year medical students. Furthermore, some teaching requirement and guidance suggestion are presented.

Aim: A new derivative LC-MS method was developed for the simultaneous determination of zofenopril and its active metabolite zofenoprilat to investigate the pharmacokinetic characteristics of zofenopril and zofenopri-lat in healthy Chinese volunteers after single and multiple oral doses of zofenopril calcium tablets. Methods: Ten Chinese healthy volunteers were given three single oral doses of 15,30, and 60 mg, respectively, and consecutively the multiple doses of 30 mg. The concentration and pharmacokinetic parameters of both the parent drug and the active metabolite were simultaneously determined by derivative LC-MS method using p-bromophenacyl bromide (p-BPB) as the derivative reagent. Results: After the single oral administrations of 15, 30, and 60 mg of zofeno-pril calcium, there was no significant difference in the t_(1/2) of both zofenopril and zofenoprilat among the three do-ses. The values of AUC_(0-24h) and c_(max) for both zofenopril and zofenoprilat showed the good linearities to the dosage over the dose range from 15 mg to 60 mg. There were no significant differences in AUC_(0-24h) and c_(max) for both com-pounds between female and male volunteers. After multiple oral administration( 30 mg once daily for 6 days ), the average steady state plasma concentration( c_(av)) for zofenopril was (5. 07 ±1. 06) ng/mL with the degree of fluctu-ation (DF) of 14. 26 ± 2. 94. The c_(av) for zofenoprilat was (6. 28 ± 1. 87) ng/mL with the DF of 11. 61 ±4. 68. The accumulation index values for zofenopril and zofenoprilat were 0. 94 ± 0. 31 and 0. 83±0. 13, respec-tively. Conclusion: Both zofenopril and zofenoprilat were demonstrated of linear kinetics after single administra-tion and showed no accumulation after multiple administration of the test zofenopril calcium tablets. There was significant difference in the pharmacokinetic characteristics for zofenopril calcium between healthy Chinese and European volunteers.

objective To investigate the association between two single nucleotide polymorphisma (SNP)rsl0053538 and r810515746 in Tim-3(T cell immunoglobulin domain and mucin domain protein 3) gene promoter region and child allergic asthma in Chinese Han population from Hubei province by using faro-ily-based association study．Methods Cenotypes of 2 SNPs(rs10053538 and rs10515746)within Tim-3 gene in 118 allergic flsthma nuclear pedigrees were analyzed by restriction fragment length polymorphism and DNA sequencing．Two family-based designs，transmission disequilibrium test(TDT)and haplotype-based haplotype relaive risk(HRR)were employed for the data analysis．Haplotypes and their frequencies in 118 nuclear pedigrees were established and analyzed by Transmit software．Results The HRR analysis showed no increased risks of contracting the disease owing to rs10053538 and rs10515746 polymorphisma of Tim-3 promoter in our 118 tries(X2=2．430，P>0．05；x2=1．368，P>O．05)．N0 transmission disequilibrium was found from heterozygous parents onto patients in our 118 tries analyzed by TDT(x2=2．042，P>0．05；X2=0．750，P>0．05)．The haplotype analysis also showed no biased transmission of rs10053538 and rs10515746 haplotypes from parents to the affected offsprings(P>0．05)．Condusion The two SNPs rs10053538 and rs10515746 in Tim-3 gene promoter region are not associated with susceptibility to child allergic asthma in Chinese Han population from Hubei province．

In part Ⅱ, are presented the results of the physical measurements, which include standing height, body weight, shoulder width and grip strength, made on children of middle school and children's homes. Pelidisi index is calculated by using Pirquet's formula. In tables 1 to 6 are tabulated the average results of boys and girls of ages from 12 to 18 years old. Since the results of children's homes differ from those of the middle schools, they are tabulated separately. The differences in standing height and body weight of these two groups of children are shown in figures 1 and 2. The children from the Homes are considerably shorter and lighter than school children of the some age range. The boys tend also to be narrower in shoulder width.Compared with the physical measurements of the children of Shenyang in the northeast China, the Cantonese children are slightly taller and heavier at the beginning of this age range but the children of the Northeast grow at a slightly more rapid rate, so that at 18 years of age, they are about 2 cm taller, with approximately the same body weight.Hand grip measurements show that girls have only 2/3 the grip strength of boys. Values of Pelidisi are calculated for a]l the children. It is found that this index does not proper]y represent the nutritional status of the children of Canton. By all the other indices of the state of nutrition used in this survey, the school children are rated as having a higher nutritional status, than those of the children's home, while the Pelidisi ratcs them lower.Nutrition is considered to be one of the factors which causes differences in the growth and development of the various groups of children compared.

This study is undertaken simultaneously with the experiments for the determination of riboflavin requirement of middle school boys in Canton. The same subjects serve in both experiments. When the loading tests are performed, 2.0 mg of thiamine is given orally at the same time the riboflavin is administered. Supplements of 0.5, 1.0 and 1.5 mg thiamine are given at the same time and in the same order as the ribofiavin. The same urine samples are analyzed for thiamine as well as riboflavin. Thiamine is analyzed by the thiochrome method of Consolazio.The thiamine content in the one-hour urine samples of the subjects before the supplement averages 5.4 to 8.9 micrograms for the 4 groups. After supplementation, the thiamine content of the fasting samples of 1.0 and 1.5 mg supplement groups show definite increase, while the other two groups remain near the same levels.After the loading test, the 4-hour total excretion amounts to about 5 per cent of the 2 mg taken, with almost no difference among the groups. When the intake of thiamine has been supplemented for two weeks, the response to the loading test varies. The 0.5 mg supplemented group excreted 4.35% of 2 mg in 4 hours, while the 1.0 and the 1.5 mg groups excreted about 8%. The hourly excretions are shown in Fig. 1. The peak of excretion of the 1.5 mg supplemented group changes from the second to the first hour after the load test. The thiamine intake of these subjects is estimated to be about 1 mg daily. They are free from symptoms associated with thiamine deficiency and their 1-hour urine samples show that the quantity excreted may be within the range considered normal for healthy subjects, yet supplementation of 1.0 or 1.5 mg of thiamine is able to cause a greater and faster urinary excretion of thiamine. An additional intake of at least 1.0-1.5 mg thiamine to their ordinary dietary intake of about 1 mg may be desirable to ensure an optimum status of thiamine nutrition in the middle school boys.