2.Alzheimer's disease and sleep disorders
Rongyan ZHU ; Peng GUO ; Wei ZHANG
Chinese Journal of Geriatrics 2017;36(1):1-4
5.Clinical application of nuclear medicine imaging in amyotrophic lateral sclerosis
Peng FU ; Lingge WEI ; Ainan GUO
Chinese Journal of Nuclear Medicine and Molecular Imaging 2014;34(3):253-256
Amyotrophic lateral sclerosis (ALS),a neurodegenerative disorder,is subtle in disease onset,difficult to diagnose,and fast-growing at progression.There.are at present little specific neurological imaging characteristics of ALS.Functional brain imaging techniques,such as SPECT and PET,were the early tools for investigation of ALS.The application of pixel-based analysis software (such as SPM) renders research in this area more convenient and objective.In recent years,improvement in brain receptor PET imaging has demonstrated its important value in the early diagnosis of ALS and evaluation of cognitive impairment.
6.Study on efficacy of Chinese herbal drugs on improving endometrial receptivity detected by using trans-vaginal three-dimensional color Doppler ultrasound in patients with thin endometrium
Hong HU ; Xiuying YE ; Yiman FU ; Wei WEI ; Peng GUO
Chongqing Medicine 2017;46(19):2635-2637
Objective To explore the clinical value of transvaginal three-dimensional color Doppler ultrasound in assessing effects of Chinese herbal drugs on improving endometrial receptivity in patients with thin endometrium.Methods A total of 76 cases of patients diagnosed with thin endometrium in Jiangbei District Hospital of Traditional Chinese Medicine from June 2015 to October 2016 were selected and treated with Chinese herbal prescription for three months.The endometrial thickness,endometrial volume and blood flow indexes before and after treatment were measured by using transvaginal three-dimensional color Doppler ultrasound.Results After 3 months treatment,the endometrial thickness and endometrial volume were increased,and the pulse index (PI) and resistance index (RI) of endometrial blood flow were decreased,compared with those before treatment,there were statistically significant differences(P<0.05).The results of three-dimensional color Doppler ultrasound indicates that after 3 months treatment the vascularization index (VI),flow index (FI) and vascularization flow index (VFI) were significantly higher than those before treatment,there were statistically significant differences (P<0.05).Conclusion The Chinese herbal prescription could increase the thickness and volume of endometrium,augment blood supply,and improve endometrial receptivity significantly.Transvaginal color three-dimensional Doppler ultrasound is a convenient and objective method for evaluating clinical efficacy of Chinese herbal prescription in patients with thin endometrium,which has high practical value.
7.Analysis of Clinical Trials about Lower Extremities Static and Dynamic Proprioception in Patients with Knee Osteoarthritis
Wei CHEN ; Yanmei GUO ; Changshui WENG ; Qiuhua WANG ; Nan PENG
Chinese Journal of Rehabilitation Theory and Practice 2011;17(1):77-79
ObjectiveTo investigate the test-retest reliability about the lower extremities static joint position sense which was tested with the Tetrax balance-test-training system, and the dynamic joint position sense which was tested with the Functional Squat System; and to investigate the relationship between the static and the dynamic joint position sense of lower extremities of the patients with knee osteoarthritis. Methods30 patients with knee osteoarthritis were tested with the lower extremities static and dynamic joint position sense twice within 7 d with the Tetrax balance-test-training system and the Functional Squat System. ResultsThe intraclass correlation coefficient (ICC) of the sum of the coefficient of medium-to-high-frequency in postural sway was 0.95 (P<0.001). The ICC of the reposition accuracy error mean of the unaffected/mild or affected/severe extremity were respectively 0.59 and 0.60 (P<0.001). The Pearson correlation coefficients of the sum of the coefficient of medium-to-high-frequency in postural sway and the reposition accuracy error mean of the unaffected/mild or affected/severe extremity were respectively 0.40 and 0.54 (P<0.05). ConclusionThe lower extremities static joint position sense test of the Tetrax balance-test-training system is well reliable, as well as the dynamic joint position sense of the Functional Squat System. They can be used together to evaluate the lower extremities proprioception in the patients with knee osteoarthritis.
8.Balance Function and Falling Risk in Elderly Osteoarthritis Patients with Single or Double Knees Pain
Yanmei GUO ; Peng HUANG ; Wei CHEN ; Weiguo JIAO ; Changshui WENG
Chinese Journal of Rehabilitation Theory and Practice 2012;18(1):25-29
Objective To explore the feature of balance function and falling risk in the elderly knee osteoarthritis patients with single knee pain or double knees pain. Methods 30 elderly knee osteoarthritis patients without pain, 30 with single knee pain and 32 with double knees pain were tested with timed up and go test (TUG), postural stability (PS), limits of stability (LOS) and dynamic fall index (DFI). Results There was significant difference in the elderly between no pain and single or double knee pain (P<0.05) in TUG, but not between the single knee pain and double knees pain (P>0.05). There was no significant difference in the elderly between single knee pain and no pain (P>0.05) in PS, but was between double knees pain and the other 2 groups (P<0.05). There was significant difference between no pain and single or double knee pain (P<0.05) in LOS, but not between single knee pain and double knees pain (P>0.05). There was significant difference between no pain and single or double knee pain (P<0.05) in DFI, and between single knee pain and double knees pain (P<0.05). Conclusion The elderly osteoarthritis patients with single knee pain are in high falling risk with their dynamic balance injury, while those with double knees pain are in higher falling risk with their static and dynamic balance injury.
9.Preparation and anti-bacterial tests of silver-modified titanium surface.
Juan LIAO ; Wei FEI ; Jun GUO ; Peng LI
West China Journal of Stomatology 2014;32(3):303-305
OBJECTIVETo deposit silver nanoparticles on a titanium surface to obtain antibacterial properties. To reduce the incidence of peri-implantitis, and improve the success rate of implantation.
METHODSA silver nanoparticle-modified titanium (Ti-nAg) surface was prepared using silanization method, and its surface was characterized by using X-ray photoelectron spectroscopy (XPS) and energy dispersive X-ray spectrometer (EDX). Two species of bacteria, namely, Staphylococcus aureus and Escherichia coli, were used to test the antibacterial effect of Ti-nAg surface.
RESULTSScanning electron microscope (SEM) revealed that a small quantity of silver nanoparticles were deposited on the titanium surface. XPS analyses revealed that 6.8% of silver was present on the titanium surface. After 24 h of incubation, 94.23% of Staphylococcus aureus and 95.34% of Escherichia coli were killed on the Ti-nAg surface.
CONCLUSIONResults suggest that silver nanoparticle-modified titanium is a promising material with an antibacterial property that may be used as an implantable biomaterial.
Anti-Bacterial Agents ; Bacteria ; Dental Implants ; Escherichia coli ; Prostheses and Implants ; Silver ; Staphylococcus aureus ; Titanium
10.Antibacterial Activity of Compounds from Rabdosia rubescens
Gaoshen LI ; Wei ZHANG ; Tao PENG ; Meizhen GUO
World Science and Technology-Modernization of Traditional Chinese Medicine 2014;(3):610-613
This study was aimed to assay the antibacterial activity of compounds from Rabdosia rubescens. Disc dif-fusion (K-B method) was used to screen the in vitro antibacterial activity. All kinds of chromatography were used to isolate the chemical constituent and structure was identified by MS and NMR spectroscopy. The results showed that six compounds were isolated and identified as oridonin (1), rosmarinic acid (2), caffeic acid (3), salicylic acid (4), ferulic acid (5), vanillic acid (6). Oridonin had activity against Staphylococcus aureus (SA), Methcillin-resistant Staphylococcus aureus (MRSA), β-lactamase positive Staphylococcus aureus (ESBLs-SA), and showed the highest ac-tivity (MIC is 3.125, 6.25 and 6.25 μg·disc-1, respectively), but was still weaker than that of berberine as positive control (MIC is 0.156 μg·disc-1). Ferulic acid had activity against SA and MRSA (MIC is 50 and 50 μg·disc-1, re-spectively). Salicylic acid had only activity against SA (MIC 50 μg·disc-1). It was concluded that oridonin, ferulic acid and salicylic acid were the main antibacterial activity compounds from R. rubescens.