0.05).However,other groups based on different extent and degree of pathology,clinical risk had significant difference in hs-CRP(P

Objective: To get the information about freshmen's mental health and it relationship with sex, city and countryside difference, and to provide the reference for effective mental health education and consultation. Methods: The situation of 1351 freshmen's mental health was surveyed by using UPI. Results: ①11.91% of the freshmen had serious mental derangement, 26.15% of them had a little psychological problem. ②The distinct difference existed not only between male and female, but also between city and countryside. The mental health of male students surpassed the female students, the city students surpassed the countryside students. Conclusion: The situation of medical freshmen's mental health should not be neglected, and its influence factors are various. Mental health education and consultation should be pointed to the students.

Objective To investigate the protective effects of Cilazapri l on focal cerebral ischemia of spontaneous hypertensive rats. Method Focal cerebral ischemia of spontaneous hypertensive rats wer e made by occlusion of the middle cerebral artery(MCA). Cilazapril treated group was taken cilazapril 4 weeks before model was made. TTC staining,HE staining,Nis sl's staining,immunohistochemistry, and image analysis were taken to estimate th e area of ischemia,number of dead neural cells,optical density of positive cell of Nissl's staining,HSP70 and NF-k BP65 immunohistochemistry reaction in ischem ia area. Result Cilazapril could reduce the area of ischemia and behavior sc ores,decrease the number of died neural ce lls,increase the optical density of positive cell of Nissl's staining,reduce th e optical density of NF-k BP65. No effect on HSP70 immunohistochemistry reactio n was found. Conclusion Cilazapril could decrease infarction of focal ischemia o f spontaneous hypertensive rats, promote the functional restoration of rats,decr ease nerve cell death,inhibit the expression of NF-k B. Cilazapril inhibited in flammatory reaction and that could be one of its protective mechanisms.

A database model of ontology was established by mining the EMR-covered data according to the con-cept of fuzzy vector space model with Kawasaki disease as an example. The evidence and model for the diagnosis and treatment of Kawasaki disease were detected fromthe EMR of Kawasaki disease in the database model of ontolo-gy in order to help the clinicians to make its differential diagnosis and improve its treatment plan, thus achieving the effective EMR data mining and promoting the computer-aided clinical decision-making.

On the basis of assuming that the postgraduate education charge is a fact,this paper at fist studies the theory and realistic basis of postgraduate student charges and then analyzes its profit and fraud. Finally,some constructive suggestions are put forward to protect the enrollment chances of poor students and the development of basic discipline.

Objective:To explore the multiple meditation effects of emotional intelligence and self-esteem between interpersonal initiative personality and social positive adaption in left-behind junior high school students.Methods:Totally 331 left-behind junior high school students [165 boys,160 girls,average age of (14.5 ± 1.2) years] were selected.They were assessed with the Interpersonal Self-Support Scale for Middle School Students (ISSS-MSS),Emotional Intelligence Questionnaire (EIQ),Rosenberg Self-Esteem Scale (RSES) and Social Adjustment Scale (SAS-YB).Results:The scores of social positive adaption were positively correlated with the scores of interpersonal initiative personality,EIQ and RSES (r ＝ 0.47-0.67,Ps ＜ 0.001).Path analysis showed that interpersonal initiative personality had direct effects on social positive adaption (β ＝ 0.47,P ＜0.001).Mediation modeling showed that interpersonal initiative personality could exert effects on social positive adaption indirectly through the mediating effect of not only emotional intelligence,but also self-esteem (x2/df＝ 3.03,TLI ＝ 0.87,CFI ＝ 0.89,RMSEA ＝ 0.08).Conclusion:The present study indicates that parallel multiple mediation model of emotional intelligence and self-esteem could explain the mechanism of influence of interpersonal initiative personality on social positive adaption appropriately.

0.05) among three groups in expression rate of CD_(40L) on B lymphocyte and CD_8~+T cells.Conclusions Abnormal level of CD_(40)/CD_(40L) what attack asthma and stable asthma showed on their relevant immune cells would have an important significance in development of allergic asthma.

Objective To study on the diagnosis methodology of breast cancer using integrated analysis of proteomics and metabonomics approach.Methods The serum samples from the 14 breast cancer patients and 7 healthy people were analyzed by two-dimensional electrophoresis in order, to find differential expressed proteins. On the other hand, an HPLC-based urinary metabonomics profiling was employed to pick out chemical patterns between breast cancer patients and healthy people.Results Glutathione S-transferase M5 was found highly expressed in the breast cancer patients′serum.The concentration pattern of S-Adenosylmethionine, Orotidine, 1-Methyladenosine and N2-Methylguanosine in patients′ urine were peculiarly different from that in the healthy people.Conclusion There are peculiar chemical pattern differentiae between the body fluid of breast cancer patients and the body fluid of healthy people. Synthetic study of cancer proteomics and metabonomics can contribute not only to prognosis of cancer but also to the pathogenesis of cancer.

Objective:To determine if growth hormone (GH) and glutamine (Gln) reduce the time and dose of parenteral nutrition (PN) in patients with short bowel syndrome. Methods: Sixteen PN-dependent patients with short bowel syndrome were randomly assigned to Group A (control, oral Gln [0.6 g/kg/d] + GH placebo + diet, n= 5), B (Gln placebo + GH [8 IU/d] + diet, n= 5), and C (Gln + GH + diet, n= 6). PN volume and content were determined by standard criteria based on clinical measurements. After 4 weeks, GH and GH placebo were discontinued, but the diet with Gln or Gln placebo was continued for 12 weeks. Results: Group B showed greater reductions in PN volume, PN calorie and PN frequency than Group A (P

AIM:Titanium-Nickel shape memory alloy(TiNi-SMA) has memory,abradability and good biocompatibility. It has different osteotomy methods and biomechanics from routine distraction osteogenesis. In this study,the dog models of mandibular defects were established to explore the effect of TiNi-SMA distractor with different osteotomy methods on mandibular distraction osteogenesis. METHODS:The experiment was performed at the animal experimental center of Sun Yat-sen University from October to December 2005. ①Eight male adult Beagle canines of 12-14 kg were selected. A 1.5 cm?1.0 cm bone defect was made in bilateral mandible of each dog. The same size transport bone disc was created mesially by osteotomy on left side and corticotomy on right side. TiNi-SMA distractor was implanted to repair defect. ②One,four,and seven days,and nine weeks after operation,the canines were radiographed for histological analysis and bone formation was observed. RESULTS:Eight dogs were all included in the final analysis. ①Gross observation found the wounds healed well without infection in all experiment dogs. ②X-ray examination showed the bone transport disc on the right side of corticotomy moved to defect area gradually after operation and filled defect area on the whole on the 7th day after operation;The bone transport disc dislocated 1 day after operation and separated from defect area totally on the 7th day after operation on the side of osteotomy(left side). ③ Histological examination demonstrated bone formed in accordance with intramembranous ossification in distraction zone and bony connection between the transport disc and mesial mandible on right side;On the left side,there was a big defect at the area of both distraction and defect zone because of dislocated bone transport disc,and no obvious new bone regeneration was found. CONCLUSION:Corticotomy can be used to establish a successfully canine model of mandibular distraction osteogenesis.