1.Esophageal Mucosal Desquamation with Hemorrhage in Bullous Pemphigoid: A Case Report.
Jun Young HWANG ; Kyung Sik PARK ; Kwang Bum CHO ; Jae Seok HWANG ; Sung Hoon AHN
The Korean Journal of Gastroenterology 2004;43(4):264-267
Bullous pemphigoid is a subepidermal blistering skin disease, usually occurred in the elderly. It is an autoimmune disease associated with circulating autoantibodies directed against structural components of hemodesmosome. Rarely, it can involve the esophagus, which can be complicated by upper gastrointestinal hemorrhage. We report a case of bullous pemphigoid with esophageal mucosal desquamation and hemorrhage in patient with chronic renal failure.
English Abstract
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Esophageal Diseases/*complications/pathology
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Female
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Gastrointestinal Hemorrhage/*etiology
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Humans
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Middle Aged
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Mucous Membrane/pathology
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Pemphigoid, Bullous/*complications/pathology
2.Coagulation Disorders in Bullous Pemphigoid and Its Mechanism.
Acta Academiae Medicinae Sinicae 2019;41(5):685-689
Bullous pemphigoid(BP)is an autoimmune blister disease caused by antibodies to the basement membrane zone.It usually exhibits tense bullae in skin and mucous membrane.BP patients can suffer from thrombosis due to hypercoagulation and/or hemorrhage due to the presence of anti-coagulation factors,which may be explained by the eosinophils,antibodies to the coagulation factors,and fibrinolytic system hyperactivity or inhibition.
Autoantibodies
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Blister
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Blood Coagulation Disorders
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complications
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Blood Coagulation Factors
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Eosinophils
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Hemorrhage
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etiology
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Humans
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Mucous Membrane
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pathology
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Pemphigoid, Bullous
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complications
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Skin
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pathology
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Thrombosis
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etiology