Objective :To investigate the clinical effect of prophylactic terminal ileostomy for protecting high-risk colorectal anastomotic stoma .Methods :Dixon operation combined with prophylactic terminal ileostomy was performed for even colorectal cancer patients with high risk of colorectal anastomotic leakage during February 2014 and October 2014 .The occurrence and outcome of complications related to anastomotic stoma were observed .Results : All the patients were dismissed from 7 to 10 days after operation .Anastomotic leakages occurred in 2 cases ,and both were slight leakages with no subjective symptom . And no specific surgical treatment was performed for them .Anastomotic bleeding occurred in 1 case and the bleeding was stopped by conservative treatment . There was no occurrence of leakage . Conclusions : Prophylactic terminal ileostomy is effective for protecting high-risk colorectal anastomotic stoma from leakage .So it is worthy of clinical promotion .