1.Pathogenesis and treatment for type 2 diabetes mellitus combined with frailty and sarcopenia
Yiyin CHEN ; Lele PENG ; Peiru HE ; Junkun ZHAN ; Youshuo LIU
Chinese Journal of Geriatrics 2021;40(1):124-127
The prevalence of type 2 diabetes mellitus(T2DM)in China is about 9.1%.Compared with healthy adults, life expectancy for patients with T2DM at 60 years of age can be cut short by 7.3-9.5 years and time for a good quality of life by 11.1-13.8 years.It is important for elderly patients with T2DM to stay functionally active.Frailty, as a common geriatric syndrome, is an important factor affecting the functional status of the elderly, a strong predictor for disability, death and hospitalization, and also a strong predictor for adverse health outcomes in elderly patients with T2DM.This article reviews the relationship between frailty/sarcopenia and T2DM, and the management and treatment of elderly T2DM patients with frailty/sarcopenia.
2.Respiratory syncytial virus infections in children with respiratory tract inflammation during winter and spring in Urumchi
Min ZHI ; Jie HE ; Bin ZHANG ; Jie DENG ; Yuan QIAN ; Peiru XU ; He SUN
Chinese Journal of Microbiology and Immunology 2011;31(4):316-319
Objective To research the infections of respiratory syneytial virus(RSV)in children with respiratory tract inflammation and define its molecular epidemic features in Urumchi.Methods SamDles were collected from November 2006 to April 2007 in the People's General Hospital of Xinjiang Uygur Autonomous Region,including 112 respiratory secretions and 280 nasopharyngeal swabs. RSV and its subgroups were detected by nested PCR.The five positive amplicons selected randomly from all positive samples were sequenced and compared with other RSV in GenBank by BLAST and DNAStar.Results of all 392specimens.68 RSV G gene segments were tested.Among them,RSV lineage A occupied 93.3%,while B occuDied 6.7%.The identities between them were 63.1%-99.4%.Phylogenetic analysis defined that they belonged to two different clusters.Conclusion RSV was one of the important viruses leading to children's respiratory tract infections in the People's General Hospital of Xinjiang Uygur Autonomous Region during winter and spring from 2006 to 2007.RSV subtype A was the prevalent genotype in the hospital dunng this epidemics.
3.Chinese experts′ consensus statement on diagnosis, treatment and prevention of Group A Streptococcus infection related diseases in children
Dingle YU ; Qinghua LU ; Yuanhai YOU ; Hailin ZHANG ; Min LU ; Baoping XU ; Gang LIU ; Lin MA ; Yunmei LIANG ; Ying LIU ; Yaoling MA ; Yanxia HE ; Kaihu YAO ; Sangjie YU ; Hongmei QIAO ; Cong LIU ; Xiaorong LIU ; Jianfeng FAN ; Liwei GAO ; Jifeng YE ; Chuanqing WANG ; Xiang MA ; Jianghong DENG ; Gen LU ; Huanji CHENG ; Wenshuang ZHANG ; Peiru XU ; Jun YIN ; Zhou FU ; Hesheng CHANG ; Guocheng ZHANG ; Yuejie ZHENG ; Kunling SHEN ; Yonghong YANG
Chinese Journal of Applied Clinical Pediatrics 2022;37(21):1604-1618
Group A Streptococcus (GAS) is a very important pathogen, especially for children.On a global scale, GAS is an important cause of morbidity and mortality.But the burden of disease caused by GAS is still unknown in China and also has not obtained enough attention.For this purpose, the expert consensus is comprehensively described in diagnosis, treatment and prevention of GAS diseases in children, covering related aspects of pneumology, infectiology, immunology, microbiology, cardiology, nephrology, critical care medicine and preventive medicine.Accordingly, the consensus document was intended to improve management strategies of GAS disease in Chinese children.