1.Study on Distribution Characteristic of TCM Syndrome Types and Its Relationship with HBVDNA and Hepatic Fibrosis Markers in Patients with HBe Antigen-Negative Chronic Hepatitis B
Peiqiong CHEN ; Jinzhen ZHANG ; Guangjun TIAN
Chinese Journal of Information on Traditional Chinese Medicine 2006;0(11):-
insufficiency of both the spleen and the kidney (type E). The serum levels of ALT and AST in type B were significantly more higher than the other syndromes (P0.05). Conclusion The distribution of TCM types of syndrome of the patients with HBeAg-negative chronic hepatitis B has its characteristic. There are some relationships between TCM types of syndrome and the levels of transaminases, HBVDNA, the abnormal rates of four hepatic fibrosis markers.
2.Correlation of Helicobacter Pylori Infection in Liver Cirrhosis of Different Syndrome Patterns with Blood Ammonia Level
Peiqiong CHEN ; Hongyan JIN ; Guangjun TIAN ; Xiaoling CHI ; Jinfeng CHEN
Journal of Guangzhou University of Traditional Chinese Medicine 1999;0(02):-
Objective To explore the correlation of helicobacter pylori(HP) infection in liver cirrhosis(LC) of different syndrome patterns with blood ammonia level.Methods Two hundred and seventeen LC patients were divided into Hp-positive group and Hp-negative group.The patients were classified into 6 syndrome patterns: liver-Qi stagnation,internal accumulation of water-dampness,stagnation of damp-heat,deficiency of liver and kidney yin,deficiency of spleen and kidney yang,and blood-stasis blocking collaterals.Parameters of blood ammonia level,hepatic function and blood coagulation function were observed in LC patients with different syndrome patterns.Results The Hp infection rate in 217 LC patients was 40.1%,the difference being insignificant in the patients with different syndrome patterns and hepatic function grading.The percentage was in a decreasing sequence in syndrome patterns of stagnation of damp-heat,internal accumulation of water-dampness,blood-stasis blocking collaterals,deficiency of liver and kidney yin,liver-Qi stagnation,deficiency of spleen and kidney yang.The difference of blood ammonia level was significant between Hp-positive group and Hp-negative group(P0.05).Conclusion Hp infection is an important factor of inducing the increase of blood ammonia level in LC.Blood ammonia level increases in LC patients after Hp infection,especially in patients with blood-stasis blocking collaterals.The hepatic function grading is corrected with blood ammonia level,the worse the hepatic function,the higher the blood ammonia level.
3.Effect of Chai Shao Liujunzi Decoction Combined with Entecavir for the Treatment of Chronic Hepatitis B:An Observation of 30 Cases
Guangjun TIAN ; Wanzhu RUI ; Peiqiong CHEN ; Xiaoling CHI
Journal of Guangzhou University of Traditional Chinese Medicine 2001;0(03):-
0.05).Normalization rate of ALT was higher in the treatment group than that in the control group (P0.05).The rate of HBeAg turning negative in the treatment group after treatment for one year was higher than that in the control group(P
4.Automated Urine Analyzer for Screening Hospital Urinary Tract Infection and Its Value
Guoqiang CHEN ; Peiqiong SHEN ; Yan SHEN ; Yaxin LIU ; Jiandong LIU
Chinese Journal of Nosocomiology 2006;0(12):-
OBJECTIVE To investigate the value of screening hospital urinary tract infection with UF-100 automated urine analyzer. METHODS It was to count the bacteria and white blood cells in 422 urine specimens with UF-100 as well as to culture the specimens quantitatively.Then the sensitivity and specificity of UF-100 counts and the correspondence of the two methods were evaluated with Yerushalmy mode. RESULTS Compared with the culture results,UF-100 showed a sensitivity of 81.5%,specificity of 63.9%,positive predictive value of 29.1%,negative predictive value of 95.0%,false positive rate of 30.5%,false negative rate of 2.8% and an accuracy of 67.2%. CONCLUSIONS The UF-100 is excellent in analyzing urine specimens,and its bacteria counts can be a valuable indicator in screening hospital urinary tract infection.
5.An Experimental Study of Phyllanthus urinaria for Counteracting Immune Liver Injury in Mice
Tianbao FENG ; Guangjun TIAN ; Hua LI ; Mingzeng TANG ; Peiqiong CHEN ; Xinhua WANG ; Fengxue ZHANG
Traditional Chinese Drug Research & Clinical Pharmacology 2000;0(05):-
Objective To evaluate the protective action of Phyllanthus orinaria(PU)for immune liver injury in mice.Methods Forty-eight NIH mice were allocated randomly to high-dose(HG)PU group,low-dose(LG)PU group,bifenbate group(BG),normal control group(NCG),and model group(MG).From the first day of establishing the models,20 g ? kg-1 of PU solution was given for gastric perfusion(GP)to HG PU group,10 g ? kg-1 of PU solution for GP to LG PU group,0.15 g?kg-1 of bifenbate solution for GP to BG group,and the equal amount of normal saline to the normal control group and the model group,qd for 12 days.Serum ALT level and visceral parameters of liver and spleen were determined,and the liver pathological feature was also examined.Results The ALT level,parameters of liver and spleen were markedly decreased in BG group(P 0.05).Conclusion PU has a good effect on counteracting the immune live injury in mice by markedly decreasing the activity of serum transaminase and visceral parameters of liver and spleen,and improving the necrosis of hepatic cells.