Objective To evaluate the abstinence rate and relapse rate of smoker with ACS after discharged from hospital, to evaluate the effect of simple smoking cessation interventions.Methods 150 smokers with ACS were collected and was divided into simple intervention group ( n = 87) and control group (n = 63) , respectively, followed up for 6 months.2 months, 6 months abstinence rate, relapse rate were compared between two groups, logistic regression model was used to analyzed the relevant factors for relapse.Results The smoking rate in patients with ACS was 31.14% , 6-month continuous abstinence rate and 6-month relapse rate was 64.6% , 36.4% , respectively.6-month continuous abstinence rate and relapse rate between simple quit-smoking intervention group and control group showed no difference.Nicotine dependence score more than 4 points can be used as predictor of relapse.Conclusions The smoking rate and the abstinence rate of smoker with ACS is higher than the general population, simple quit-smoking intervention do not increase the success rate of quit-smoking, indicated the need to strengthen the intervention in patients with ACS and smoking.

OBJECTIVETo determine the association of cigarette smoking and coronary artery diseases (CAD).

METHODSA case-control study involving 355 people classified as CAD or without CAD was performed. But people treated with diuretic, aspirin, lipid-lowering agents, heparin or those with renal, hepatic diseases were excluded. Gender, age, body mass index, plasma glucose under fasting, total cholesterol, triglyceride, high-density lipoprotein cholesterol, low-density lipoprotein cholesterol, fibrinogen, cigarette smoking consumption grade (0: no smoking, 1: less or equal 100 cigarette year, 2: one hundred cigarette year < cigarette index

RESULTSIn multiple logistic regression, age, gender, fasting plasma glucose, fibrinogen and cigarette smoking showed significant independent association with CAD. Compared with non-smoker, the odds ratio (OR) of CAD of grade 3-cigarette smoking was 3.519 (95% CI: 1.538 - 8.053, P = 0.003). However with grade 1 cigarette smoking group, no significant independent association was found with CAD (OR = 0.948, P = 0.959). With more than grade 2 [grade 2 + 3, compared with less than grade 2 (0 + 1)] and grade 3 [compared with less than grade 3 (0 + 1 + 2)] cigarette smoking, ORs of CAD were 2.094 (P = 0.027), 3.463 (P = 0.002) respectively. Three hundred fifty-five people were divided into 3 groups: control, stable angina (SA) and unstable angina (UA) groups. In multinomial logistic regression, when comparing with UA, parameter estimate of cigarette smoking degree in the SA group were beta = -0.220, s(x) = 0.138, P = 0.112, OR = 0.803 respectively.

CONCLUSIONSCigarette smoking was a significant independent risk factor for CAD. With more cigarettes smoked, a higher odds ratio of CAD was seen. Gender, age, fibrinogen and plasma glucose during fasting were also independent factors significantly associated with CAD. No significant independent association between cigarette smoking and unstable angina was found.

Case-Control Studies ; Coronary Artery Disease ; epidemiology ; etiology ; Female ; Humans ; Male ; Middle Aged ; Odds Ratio ; Risk Factors ; Smoking ; adverse effects