Objective:To understand the levels of serum cholesterol in patients with gastric cancer and gastric ulcer before and after operation,and to study the relationship between the level of serum cholesterol and the tissues differential degree of gastric cancer.Methods:To survey the content of serum cholesterol in patients with gastric cancer and patients with gastric ulcer confirmed clinically before and after operation,looking through the medical records of the patients and taking notes about the tissues differentiated degree of the gastric cancer,then making the statistical analysis.Results:Comparing with the normal control group,the level of serum cholesterol in gastric cancer decreased obviously before operation,there was obvious statistical difference(P0.01),and increased after operation,comparing with themselves before operation was statistical difference(P0.05),and no statistical difference comparing with the normal control group after operation.There was statistical difference between the higher(group A)and the lower(group B)differentiated degree of gastric cancer tissues(P0.05)before operation and no statistical difference after operation.After operation the levels of serum cholesterol in group A and group B were all increased.Comparing with the level of serum cholesterol before operation each other,there was obvious statistical difference(P0.01)in group B and no statistical difference(P0.05) in group A.Conclusion:The level of serum cholesterol in patients with gastric cancer decreased before operation and increased after operation,especially in progressive gastric cancer.There was correlation between the level of serum cholesterol and the tissues differentiated degree of gastric cancer.The lower the tissues differentiated degree of gastric cancer was,the lower before operation and the higher after operation the level of serum cholesterol were.

The characteristics of non-arteritic anterior ischemic optic neuropathy (NAION) include sudden decline of visual acuity, sector-shaped visual field defect connected with the physiological blind spot or hemi-visual field defect, and optic disc edema. Early angiographic abnormalities of optic disc and peripapillary choroidal circulation are important cues for the diagnosis. Angiography combined with visual field test can make the diagnosis more accurate. The pathological mechanism and process of NAION and ischemic cardiovascular/cerebrovascular disease are essentially the same. There are several critical issues in this field we need focus on, including strengthening the cooperation with relevant professional disciplines; improving the ocular ischemia through drugs, intervention and other means; preventing more serious cardiovascular events and intervening in a number of high-risk populations to reduce the incidence of AION.

This study demonstrated with the immunocytochemical ABC method that thedistribution pattern of TH,5-TH,SP,L-ENK and OXY immunoreactive fiberswere alike in the intermediate zone of the thoracic and upper lumbar spinal cord.These fibers located in the lateral funiculus,lateral horn,intermediate gray and thearea surrounding the central canal,forming a transversal fiber band with most ofthe fibers in the lateral horn.In the lateral horn,TH,5-HT,SP and L-ENKimmunoreactive fibers and terminals aggregated in fiber clusters and numerous fib-ers made up a longitudinal bundle running through the fiber clusters.These immuno-reative fibers and terminals surrounding the central canal and distributed mainly dorsalto it.TH and 5-HT fibers accumulated in midplane where some fibers ran in alongitudinal fiber bundle and bilateral fibers and terminals distributed sparsely.SP and L-ENK fibers and terminals were relatively less in the midplane whiledense laterally.All kinds of the immunoreactive fibers were found close to theependyma.Two small 5-HT fiber bundles ran parallel and lateral to the centralcanal and a small SP fiber bundle ventral to it.Moderate immunoreactive fiberswere found periodically in the intermediate gray and formed distinct bands to linkfiber clusters in the lateral horn and fibers dorsal to the central canal.The imm- unoreactive fibers in lateral funiculus accumulated near the lateral horn and mostdensely in upper thoracic cord.OXY-containing fibers were much less than theothers,thus obvious fiber clusters,longitudinal bundle or transversal bands had notbeen found.In general,the distribution pattern of some monoaminergic and pepti-dergic fibers in the intermediate zone was provided with a laddershaped configura-tion.The two longitudinal immunoreactive fiber bundles——dorsal to the centralcanal and within the lateral horn,located medial and lateral in the spinal grayrespectively,and the transversal bands appeared periodically in the intermediate graybridging between the two longitudinal bundles.This configuration of immunorea-ctive fibers coincided with nuclear regions which contained preganglionic sympatheticneurons as well as their dendrites.

Objective To evaluate the level of serum cholesterol in patients with progressive gastric cancer and gastric ulcer before and after operation, and the relationship between the level of serum cholesterol and the clinical differential degree of progressive gastric cancer . Methods To measure the content of serum cholesterol in patients with progressive gastric cancer and gastric ulcer before operation and after operation 10 day. The size of tumor, infiltration, metastasis and the pattern of the operation were studied statistically. Results The level of serum cholesterol in group of progressive gastric cancer was significant lower than that of normal control group(P 0.05 ) in group A, but there was significant difference in group B after the operation(P

5.16 log of K562, U937, HIMeg and HL60 cells, respectively, but spare 23.37 ? 25.66% of normal CFU-GM (0.63 log killing). When HL60 cells mixed with normal mononucleated bone marrow cells in 1:9 ratio were studied, the killing of HL60 colonies was more than 4.29 log. The result suggested that photocarcinorin plus light could eliminate leukemic progenitors, and might be used in clinical ABMT. Several factors that might affect the photosensitization effect on cells were discussed.

Objective To find out the situation of laboratory testing capacity of fluoride in drinking water in Guizhou Province.Method Assessment of fluoride detection capabilities in nine cities (states) and 31 countylevel laboratories of the province in 2010 was carried out,the test results of individual indicators were evaluated using a single Z-score method,and the determination was based on the fluoride ion selective electrode method of Drinking Water Saritary Standard Test Method (GB/T 5750.5-2006) or fluorine reagent spectrophotometry.Results The feedback rate of fluoride measurement results was 100％,the satisfactory rate of laboratory results was 82.5％,the suspicious rate of results was 7.5％(33/40),and the unsatisfied rate was 10.0％(3/40).Conclusion The fluoride detection capability of most laboratories that participated in the proficiency test has met the requirements,and 10 percent of the laboratory's capacity needs to be improved.

Objective To observe the cilioretinal artery and its relationship with central visual loss in central retinal artery occlusion(CRAO) patients.Methods A total of 140 CRAO patients (140 eyes) were enrolled in this study.The patients included 83 males and 57 females.The age was ranged from 42 to 75 years old,with an average of (55.70 ± 22.20) years.All the patients were affected unilaterally,including 79 right eyes and 61 left eyes.The disease duration was from 1 to 10 days,with a mean of (4.7±3.9)hours.Central vision and fluorescence fundus angiography were measured for all patients.The central visual loss was divided into 3 types:mild (≥0.1),moderate (finger counting to 0.08) and severe (no light perception to hand movement).The number,length and location of cilioretinal artery were observed.The correlation between cilioretinal artery and central visual loss was analyzed.Results There were 41 eyes (29.3％) with cilioretinal artery,which including 13 eyes (31.7％) with ≥3 cilioretinal arteries,23 eyes (56.1％) with 2 cilioretinal arteries,5 eyes (12.2％) with 1 cilioretinal arteries.The cilioretinal artery was within 1 disk diameter (DD) in length and not reached the macular area in 37 eyes (90.2％),was more than 1DD in length and reached the macular foveal area in 4 eyes (9.8％).The cilioretinal artery located in the temporal side of optic disk in 29 eyes (70.7％),and in other quadrant in 12 eyes (29.3％).The distribution of central visual loss degree as follow:mild in 15 eyes (10.7％),moderate in 50 eyes (35.7％),severe in 75 eyes (53.6％).The difference of central visual loss in the eyes with or without cilioretinal arteries was not significant (x2=0.16,P＞0.05).Conclusions Cilioretinal artery exists in 29.3％ CRAO eyes.There was no close correlation between cilioretinal artery and central visual loss.

Objective To study the role of bile reflux in the pathogenesis of stress ulcer after acute brain trauma in rat. Methods The animal model was reproduced by Allen's method with modification. The bile acid concentration in the stomach and blood, the pH value of the gastsic content, and ulcer index (UI) were assayed 1, 3, 6, 24 hour after the stress, and they were compared with that of sham injury group. Results In stress group, compared with sham injury group, the amount of bile acid in the stomach was notably increased( P

The synaptic organization of monoaminergic and peptidergic fibers in the lateral horn of the rat spinal cord was studied under electron microscopy by immunocytochemistry ABC method. TH, 5-HT, SP and L-ENK immunoreactive fibers in the lateral horn were unmyelinated. In the cell clusters of the lateral horn these fibers appeared in the space between cell bodies and some pressed on the soma, but axosomatic synapses were seldom found. Many immunoreactive fibers ran along the dendrites, especially in the dendritic bundle. Occasionally a small bundle of unmyelinated fibers all contained the same kind of substance. Majority of the immunoreactive boutons formed axodendritic synapses. All the four kinds of neuroactive substancecontaining boutons or varicosities contained almost round clear vesicles or plus a few large granular vesicles. The SP and L-ENK varicosities included more large granular vesicles than the boutons did. Both symmetrical and asymmetical contacts were encountered in TH, 5-HT, SP and L-ENK boutons.

005,?=2), but they were significantly higher than that of PB(0%, 0/12) as well as liver cirrhosis (LC) tissues (8%, 1/12) in LC group (12 cases), respectively (2)A total of 3 homozygous deletions and no point mutations of exon 1 and 2 in p16 gene in HCC were found (3)The discrepancies of the positive rates of HBV- DNA integration among normal liver (14%, 2/14), LC(67%, 8/12) and HCC (97%, 28/29) were statistically significant (?2=29434*!5, P