1.Influencing factors of mandible osteoporosis
Zengning LI ; Peikai SHI ; Fusheng DONG
Chinese Journal of Tissue Engineering Research 2006;10(24):190-192
OBJECTIVE: With the prolongation of life span, more and more people care their health. In this paper we summarized the studies about correlative factors of mandible osteoporosis so as to investigate the cause of osteoporosis and how to inhibit or postpone the occurrence of mandible osteoporosis and improve people's quality of life.DATA SOURCES: We searched Qsinghua Tongfang Database for papers about mandible osteoporosis published between January 1991 and May 2005 with the key words of "osteoporosis, mandible bone, alveolar bone"in Chinese. Meanwhile, related English literatures were also searched in Medline between January 1975 and May 2005 with the same key words.STUDY SELECTION: The literatures included all the related papers of correlative factors of mandible osteoporosis. Inclusive criteria were: the study types were randomized controlled trials, drug stress test and clinical drug effect test; the samples were both human and animals. Exclusive criteria: Reviews and literatures without controls were excluded.DATA EXTRACTION: Totally 182 literatures related to the correlative factors of mandible osteoporosis were collected, and 36 were accorded with the inclusive criteria. The excluded were 146 papers of repeated drug effect study.DATA SYNTHESIS: A total of 36 papers including 5 321 human and 152 animals analyzed the data of correlative factors of mandible osteoporosis in age, sex, hormones, biting force, physical training and living habit,etc., respectively, which included 6 interfere-test papers of ovariactomized rats.CONCLUSION: It is concluded that mandible osteoporosis can result in a part of bone mine loss, which is related to age, sex, hormones, biting force,physical exercise and living habits, and so on.
2.Evaluation of Drug Abuse Prevention and Treatment Program among Drug Users
Jian LUO ; Peikai LI ; Huaihai SHI
Chinese Mental Health Journal 1989;0(03):-
Objective:To evaluate the efficacy of drug abuse prevention and treatment and the needs of drug users.Method:A multi-center survey was carried out with a self-designed questionnaire in 10 compulsory detoxification centers among 2400 drug users.Results:The results of the survey indicate that 76.2% of the subjects had never received any drug abuse prevention education before they using drugs. However, 53.6% of the subjects who received drug abuse prevention education thought that the promotion and education are not helpful or hardly helpful. Drug abusers were basically satisfied with most "software" and "hardware" services of the present compulsory drug abuse center. What should be improved is the effectiveness of treatment. Meanwhile, Drug abusers thought that the most urgent needs were: learning skills to prevent relapse; helping to improve living surrounding and helping to find jobs etc.Conclusion:The coverage of the present drug abuse prevention education is not wide enough and need to be improved in its effectiveness and orientation. In order to make drug abuse treatment more effective and meet drug abusers' needs, multi-department and cross-discipline cooperation, exploration and efforts from the whole society are necessary.
3.The Influence of Methadone Maintenance Treatment on Family Function of Heroin Addicts
Peikai LI ; Jian LUO ; Cunmin ZHANG
Chinese Mental Health Journal 1989;0(03):-
Objective:To study the family function of heroin addicts who accept methadone maintenance treatment.Methods:96 heroin addicts who accept methadone maintenance treatment were identified as study group, while the control were 36 heroin addicts in community.Family Assessment Device (FAD) was used to assess the outcome.Results:After 1 year intervention, the study group made much progress in each subscale .The scores of Problem Solving(2.2?0.4), Communication(2.2?0.3), Roles(2.4?0.3), Affective Responsiveness(2.4?0.5) and General Function(2.2?0.4)of the study group were higher than that of control group significantly(PS=2.3?0.4,CM=2.6?0.3,RL=2.5?0.3,AR=2.6?0.3,GF=2.5?0.3,t=1.962~6.744,P
4.Comparison of artificially double-acting avascular replacement and PFNA internal fixation for intertrochanteric fractures in elderly patients
Yibiao LI ; Ruixin CAI ; Peikai CHENG ; Wei HUANG
Journal of Regional Anatomy and Operative Surgery 2016;25(9):680-683
Objective To observe the clinical efficacy of bipolar hemi arthroplasty and PFNA internal fixation for elderly patients with unstable intertrochanteric fracture.Methods The data of 79 elderly patients with unstable intertrochanteric fracture in our hospital from Au-gust 2013 to August 2014 were analyzed retrospectively.According to different surgical methods,79 cases were divided into observation group (n =40)and control group(n =39).The observation group were treated by artificially double-acting avascular replacement,and the control group received PFNA internal fixation.The operation time,intraoperatve blood soss,bedridden time,clinical effecacy and complications were recorded and observed.Results The operative time and bed time of observation group were significantly shorter than those of control group, the difference was statistically significant(P <0.05).The total postoperative complication rate of observation group was 20.00%,which was higher than 20.51% of control group,the difference was statistically significant (P <0.05).The Harris scores in observation group 3 months and 6 months after surgery were significantly higher than those in control group,the differences were statistically significant(P <0.05).Con-clusion Both artificially double-acting avascular replacement and PFNA internal fixation have a good effect on elderly patients with unstable intertrochanteric fracture.The artificially double-acting avascular replacement has the advantages of less blood loss,faster recovery and less postoperative complications,which is conducive to improving the quality of life of patients.
5.Effects of different skin expansion ways on collagen and actin
Wenbin SHI ; Yuying DONG ; Fusheng DONG ; Peikai SHI ; Guiyun REN ; Jianying LI
Journal of Practical Stomatology 2010;26(1):38-42
Objective: To understand the effects of different expansion ways on collagen and actin of skin and to provide an experiment foundation for the suitable expansion method clinically. Methods: The rabbits were divided into five groups. The expanders were embedded in experimental group. The sirius-red specific staining method was applied to observe the changes of type I collagen and type III collagen and their proportion. Immunochemistry method was used to detect the expression of actin. Results: 1: In group A, B and C, type I collagen arranged turbulently and was thicker and type III collagen decreased relatively at earlier maintaining period. After 4 week, type I collagen arranged regularly and type III collagen was relatively increased. 2: Comparisons of the area about type I, III collagen: At the same maintaining period, there were no significant difference among the group A,B and C. With the extension of maintaining period, the area of type I, III collagen increased gradually, but there was inclined to stabilize at the fourth week in group A, B and at the third week in group C. Comparison of the proportion of collagen I and collagen III: There were significant difference between group A, B and group D, but no significant difference was observed after the fourth week. There were significant difference between group C and control group, but no significant difference was observed after three week. 3. With the extension of maintaining period, the positive expression rates of actin decreased gradually in group A, B, C. At the same maintaining period, significant difference were observed among group A, B, C. The positive expression rates of actin in group C were lower than that of group A at the same maintaining period. Conclusion: The repeated rapid expansion can not only shorten the clinical period but also promote the quality of skin flap. It is a safe and feasible method in clinic.
6.Ten years of follow-up study on committed suicide and attempted suicide in Jinuo nationality
Xiaoyan LIU ; Xiaobin YANG ; Qiuyuan LI ; Zuxin ZHU ; Hongyi LI ; Lian LIU ; Hongchun GENG ; Liqin XIE ; Peikai LI ; Yong ZENG ; Jianzhong YANG
Chinese Journal of Behavioral Medicine and Brain Science 2011;20(4):339-341
Objective To investigate the recent decade (1999 to 2009) incidence of committed suicide and attempted suicide of the Jinuo nationality in Jinuo Mountain and study the clinical characteristics of it. Methods 10 610 subjects at 44 Jinuo villagers committees were investigated by the method of door-to-door inquiry under the help of clues and collected the data of larithmics and medical history. Results 32 committed suicide patients were found in total, and the average incidence rate per year in the recent decade was 30. 16/100 000. 5 attempted suicide patients were found and the average incidence rate per year in the recent decade was 4.71/100 000. Conclusion The Jinuo committed suicide incidence rate is higher than nationwide level. The attempted suicide incidence rate is lower than nationwide level.
7.Meta-analysis of the effect of platelet-rich fibrin in alveolar ridge preservation
DONG Jingbo ; LI Zhenzhen ; LIU Chenxi ; SHI Peikai
Journal of Prevention and Treatment for Stomatological Diseases 2021;29(2):95-105
Objective :
To evaluate the effect of platelet-rich fibrin (PRF) on alveolar ridge preservation after tooth extraction.
Methods:
Randomized controlled trials (RCTs) published before August 25, 2020 about the use of PRF after tooth extraction were searched through the PubMed, Embase, Cochrane Library, HowNet, Wanfang, CBM databases and clinical trial registration centers in China and the United States. Outcome indicators included in the studies included dry socket occurrence, alveolar bone resorption in the horizontal and vertical directions, and the percentage of new bone. Meta-analysis was conducted with Review Manager Version 5.3 software.
Results:
A total of 706 studies were retrieved. After screening, 8 studies were analyzed quantitatively. Meta-analysis results showed that PRF could reduce the absorption of alveolar bone after tooth extraction, which reduced the horizontal bone mass (WMD=-0.71, 95% CI=-1.11 to -0.32, P < 0.05) and buccal (WMD=-1.38, 95% CI =-1.87 to -0.88, P < 0.05) and lingual sides (WMD=-0.49, 95% CI=-0.92 to -0.06, P < 0.05) and increased the percentage of new bone (SMD=1.24, 95% CI =0.25 to 2.23, P < 0.05). However, there was no significant difference in preventing the occurrence of dry socket (RD < 0.01, 95% CI=-0.05 to 0.04, P=0.95) and reducing bone absorption in the vertical direction of mesial (WMD=-0.11, 95% CI=-1.17 to 0.95, P=0.84) and distal (WMD=-0.66, 95% CI=-1.93 to 0.60, P=0.30) alveolar ridge after tooth extraction.
Conclusion
Using PRF alone after tooth extraction can effectively preserve bone mass in the horizontal direction of the alveolar ridge and the vertical direction of the buccal and lingual sides.
8. Clinical analysis of 30 cases of Castleman disease with different types of thoracic involvement
Xiaoxian ZHANG ; Lei JIANG ; Chunyan WANG ; Yingying GU ; Longguang LI ; Tingting XIA ; Ying HUANG ; Peikai HUANG ; Qingling ZHANG
Chinese Journal of Hematology 2020;41(2):149-156
Objective:
To improve the clinical understanding of Castleman disease (CD) with different types of thoracic involvement, including their clinical features, radiological and pathological findings, diagnosis and current treatment strategies.
Methods:
Retrospective analysis of 30 patients diagnosed with CD with thoracic involvement and hospitalized between June 2009 and May 2019 in The First Affiliated Hospital of Guangzhou Medical University was performed. Patients were divided into three groups for subsequent analysis based on the clinical data: CD with bronchiolitis obliterans (BO) , unicentric Castleman disease (UCD) without BO, and multicentric Castleman disease (MCD) without BO.
Results:
Among the 30 patients, there were 5 (16.7%) patients diagnosed with BO, 18 (60.0%) patients had UCD without BO and 7 (23.3%) patients had MCD without BO. The average age of MCD without BO patients was significantly older than that of BO and UCD without BO patients[ (49.29±5.39) ys