Since the first edition of ISO15189"Medical laboratories: requirements for quality and competence" was published in 2003, it has been rapidly and widely used in the world under the promotion of the International Laboratory Accreditation Cooperation Organization (ILAC), and has become the basic standard for the quality management, capacity-building and capacity attestation of medical laboratories. The Mutual Recognition Arrangement (MRA) of ILAC for ISO15189 is the most authoritative international permit for examination results, which is accepted by international organizations. Since the establishment of ISO15189 medical laboratory accreditation system in 2004 in China, more than 530 medical laboratories have been accredited, which plays an important role in improving the quality and competence of medical laboratories in China, and improves the influence of Chinese medical laboratories in the world. ISO 15189:2012 is currently being revised by the International Organization for Standardization/Technical Committee on Clinical Laboratory Testing and in vitro diagnostic test systems (ISO/TC212). This revision will bring significant changes and the medical laboratory shall pay attention to these changes. In order to help medical laboratories understand the new ideas in advance, this paper summarizes and analyses the draft of the new international standards, and provides references for users.

Extrarenal Wilms′ tumor is extremely rare and has no characteristic clinical manifestations. Diagnosis is difficult before surgery, and is often confirmed by histopathology. Comprehensive treatment by surgery, chemotherapy and radiotherapy is currently adopted for such patients, and the overall survival rate can reach about 90%. Here we report a 2-year-old child with Wilms′ tumor in the left scrotum.

Objective:To evaluate the clinical efficacy and safety of external application of Dafengziointment in the treatment of adult chronic eczema .Methods:A total of 122 patients with adult chronic eczema ,admitted during Jan .2013 and Mar . 2015 ,were randomly divided into the treatment group (n= 60) and the control group(n= 62) .Both two groups received external application of ointment based on the oral formula of traditional Chinese medicine .The treatment group was given external application of Dafengzi ointment (twice daily ) , while the control group was given external application of Binghuang f ule ointment (twice daily) .And one course of treatment included 4 weeks of continuous application .The patients’ symptom integral and adverse reaction in two groups before and after one course of treatment were observed and recorded ,and the clinical curative effect and safety of the medication for external use was evaluated .Results: There was no significant difference regarding the total effective rate between the treatment group and the control group .The statistical analysis on each symptom integral for patients in two groups showed that ,the treatment group was superior to the control group on relieving pruritus and other local lesions such as rough ,cornification ,desquamation ,and lichenification ,as well as improving sleep quality (P<0 .05) .There was no local or systemic adverse reactions in both two groups during the treatment .Conclusions:The curative effect of external application of Dafengzi ointment in the treatment of adult chronic eczema is certain ,and it is safe and reliable .Thus ,it is worthy of clinical popularization .