Objective To observe the effect of no tension repair in the treatment of inguinal hemia.Methods Notension hernia repair was used to treat 630 patients with inguinal hernia(648 sides):primary indirect inguinal hernia in 604 cases( 18 cases of bilateral),primary direct inguinal hernia in 15 cases(2 cases complicated with indirect inguinal hernia,1 case of double direct inguinal hernia complicated with the right indirect hernia),recurrent hernias( 11cases).The mesh plug and patch of American Bard Company production was selected as hernia repair material for inguinal hernia repair.The operation time,the wound pain day,postoperative ambulation time,complications,and the recurrence rate was observed.Results 630 cases were all successful in operation,and the operation time was 40 ～110min,average operation time about 50min.6 -24h after operation all patients were got out of bed.29 cases of the postoperative urinary retention,indwelling catheter 24 hours to 1 week;6 cases of the fat liquefaction under the incision;3 cases of postoperative foreign body sensation;recurrence in 2 cases(3 sides),1 case of bilateral infected and recurrence ; 11 cases of local swelling incision; 16 cases of incision with mild foreign body sensation.8 days after operation all patients were discharged.Conclusion The no tension repair in the treatment of inguinal hernia had good effect and low recurrence.

Objective To investigate the principles of diagnosis and treatment of postoperative intestinal obstruction.Methods The clinical datas of 89 cases of postoperative intestinal obstruction treated from 2001 to 2005 were analyzed retrospectively.Results All the 89 cases were cured without severe complications such as intestinal fistula and no death.The early postoperative inflammatory intestinal obstruction occurred in 2 cases.Recurrent intestinal obstruction occurred in 2 cases.Conclusions Intestinal obstruction can be caused by operation in abdomen.The diagnosis depends on the medical history,clinical manifestations,abdominal plain X-ray and computed tomography.Therapeutic procedure and operative opportunity play an important role in the treatment of postoperative intestinal obstruction.Non-operative approach should be the first choice for early postoperative inflammatory intestinal obstruction.Prompt surgery is clearly indicated and valuable for acute or being strangulative obstruction.Active operative treatment should be considered in recurrent chronic intestinal obstruction.

Objective To study the corelation between the expression of COX-2 and postoperative adhesions and to determine the effect of COX-2 selective inhibitor,Celecoxib,on postoperative adhesion formation. Methods Fifty SD rats were randomly assigned to five groups each consisting of 10 rats,Study groups were as follows:(A)positive control group,(B)sodiumhyahronate group,(C)low dose Celecoxib group,(D)high dose Celecexib group,(E)negative control group,Five rats in each group were treated accordingly for consecutive 8 days and 15 days respectively and sacrificed,After treatment,intra-abdminal adhesions were scored using a standard method.The adhesions tissure and injured peritonaeum were subjected to Westem-blotting to detect the expression of COX-2. Results The level of postoperative adhesions and expression of COX-2 of sodiumhyahronate group、low dose Celecoxib group、high dose Celecoxib group were lower than that of positive control group(P<0.05),Sediumhyahronate treatment group was different formthe two Celecoxib treated groups(P<0.05).Conclusions Selective COX-2COX-2.mechanism,provides durable inhibition of intra-abdominal adhesions through an antiangiongenic COX-2 mechanism.

OBJECTIVETo evaluate the effect of hemoperfusion on tetramine poisoned patients.

METHODSThree tretramine poisoned cases treated with hemoperfusion were selected. The samples during and after hemoperfusion were collected and analyzed by gas chromatography.

RESULTSTetramine concentration at the inlet of the artificial kidney kept the same level during hemoperfusion. After hemoperfusion, the tetramine concentration in patient plasma changed little in 72 hours. 1.03-1.55 mg of tetramine was adsorbed by the instrument of hemoperfusion after two hours' hemoperfusion.

CONCLUSIONAlthough hemoperfusion was not so effective to reduce blood tetramine concentration in patients, it could clear about 1 mg tetramine for one time.

Bridged-Ring Compounds ; blood ; poisoning ; Chromatography, Gas ; Hemoperfusion ; Humans