1.Micromechanical properties of articular cartilage resilience under different compression conditions
Xifan XU ; Lilan GAO ; Yutao MEN ; Peibei DONG ; Chunqiu ZHANG
Chinese Journal of Tissue Engineering Research 2017;21(20):3147-3151
BACKGROUND: It is of great significance to study the resilience of articular cartilage for human daily routine and their match quality. OBJECTIVE: To analyze the micromechanical properties of articular cartilage resilience under different loads and at time points. METHODS: The swine cartilage samples coated with tracers were compressed using the MTF-100 tensile machine, and the cartilage compression and resilience were recorded by CCD. Images were processed using digital image correlation technology.RESULTS AND CONCLUSION: During resilience, the strain value on the superficial surface of the cartilage was decreased most, successively followed by the middle layer and the deep layer, while the time of a decrease from 20%, 10% and 6% to 3% was similar. The longer the resilience time was, the more slowly the strain changed in different layers of the cartilage, but the ultimate strain was less than 1%. On the same layer under different compressive stress, the larger load caused faster strain change firstly, and then the smaller load brought about faster strain change. The effect of different continuous compressive time on the same layer of cartilage was similar with the load. These results showed that 90% resilience of the articular cartilage occurred within the first 15 minutes. The mechanical resilience of different layers of the articular cartilage has a close relationship with the loading and the loading time, and both compressive time and loading do harm to the resilience of articular cartilage. Besides, the cartilage will rebound to the state before compression.
2.Postoperative nursing for edge-to-edge repair in the treatment of mitral valve insufficiency
Peibei GAO ; Zhengwei GU ; Lijie WANG
Journal of Clinical Medicine in Practice 2014;(14):7-9
Objective To summarize the postoperative nursing experience on 25 patients with edge-to-edge repair in the treatment of mitral valve insufficiency.Methods The postopera-tive nursing strategies mainly included maintaining stable hemodynamics and effective respiration, preventing low cardiac output syndrome and cardiac temponade,correcting arrhythmia timely,pro-tecting renal function,and anticoagulation therapy.Results One patient suffered from low cardiac output syndrome,and 6 patient s experienced arrhythmia.All of them got recovered after treat-ment.Every patient was discharged on the 8th postoperative day.Conclusion With effective nursing strategies for patients after edge-to-edge repair in the treatment of mitral valve insufficien-cy,various complications could be recognized and treated in time,the perioperative efficacy are im-proved and recover of patients could be promoted.
3.Postoperative nursing for edge-to-edge repair in the treatment of mitral valve insufficiency
Peibei GAO ; Zhengwei GU ; Lijie WANG
Journal of Clinical Medicine in Practice 2014;(14):7-9
Objective To summarize the postoperative nursing experience on 25 patients with edge-to-edge repair in the treatment of mitral valve insufficiency.Methods The postopera-tive nursing strategies mainly included maintaining stable hemodynamics and effective respiration, preventing low cardiac output syndrome and cardiac temponade,correcting arrhythmia timely,pro-tecting renal function,and anticoagulation therapy.Results One patient suffered from low cardiac output syndrome,and 6 patient s experienced arrhythmia.All of them got recovered after treat-ment.Every patient was discharged on the 8th postoperative day.Conclusion With effective nursing strategies for patients after edge-to-edge repair in the treatment of mitral valve insufficien-cy,various complications could be recognized and treated in time,the perioperative efficacy are im-proved and recover of patients could be promoted.
4.Examining core symptoms and influencing factors of patients with gastric cancer undergoing chemotherapy:the role of Traditional Chinese Medicine constitutional traits
Yanling ZOU ; Yi LI ; Ziyan ZHANG ; Xun LI ; Lihua YANG ; Xiaoqing WANG ; Juan GAO ; Huiyun GUAN ; Peibei DUAN
Chinese Journal of Nursing 2024;59(18):2238-2243
Objective To investigate the incidence and severity of symptoms in patients with gastric cancer who received chemotherapy,we constructed a symptom network to explore core symptoms and bridge symptoms.Furthermore,the study explores the association between core symptoms and Traditional Chinese Medicine(TCM)constitutions.Methods Patients with gastric cancer who received chemotherapy in the medical oncology and surgical oncology department from March to August 2023 were selected for the study using a convenience sampling method.The MD Anderson Symptom Inventory Gastrointestinal Cancer was used for evaluating gastrointestinal symptoms and their severity among patients receiving chemotherapy for gastric cancer,as well as assessing the classification of TCM constitution among patients.The symptom network model was constructed using the R programming language,and the central index was analyzed to determine the core symptoms and bridge symptoms.Binary logistic regression analysis was employed to assess the association between different physical conditions and the occurrence of core symptoms.Results A total of 346 electronic questionnaires were collected,with 340 valid ones,and the effective recovery rate was 98.3%.The 3 most prevalent and severe symptoms among the 340 patients with gastric cancer were fatigue(85.59%),lack of appetite(82.35%),and taste alteration(81.18%).The centrality index results indicated that grief exhibited the highest intensity,medium,and compactness centrality values(rs=8.23,rb=2.00,rc=0.03),making it the core symptom of this condition.Sleep disorders,lack of appetite,drowsiness,and taste alteration were identified as bridging symptoms with bridge intensities of 0.74,0.76,0.99,and 0.94 respectively.The results of Spearman correlation analysis showed that there was a positive correlation between sadness and qi-deficiency constitution,phlegm-dampness constitution(P<0.05).The phlegm-dampness constitution was positively correlated with the taste alterations(P<0.05).Conclusion In patients with gastric cancer,fatigue emerges as the most prominent symptom,while sadness assumes the core symptom.Additionally,sleep disorder,lack of appetite,drowsiness,and taste alteration are bridge symptoms.According to the principles of TCM constitution,qi-deficiency and phlegm-dampness are constitutions associated with a higher risk of experiencing sadness,and phlegm-dampness is a constitution associated with a higher risk of taste changes.Nurses can integrate core symptoms and TCM constitutions characteristics to optimize the strategies for symptom intervention.