1.Ectopic pregnancy after in vitro fertilization and embryo transfer:clinical analysis of 55 cycles
Journal of Chongqing Medical University 2007;0(09):-
Objective:To study the incidence,risk factors and clinical manifestaion for ectopic pregnancy(EP)after in vitro fertilization and embryo transfer(IVF-ET). Methods:A retrospective study of IVF and intracytoplasmic sperm injection (ICSI) pregnancies was performed between January 2002 and July 2005. Results:A total of 668 woman conceived after IVF or ICSI were studied. The rate of EP was 8.2%,corresponding with 55 Eps,of which 15 were heteropic pregnancy(HP). There were 40 Hps in tubal facter group,There apper to be no relationship between d2 ET and d 3 ET,ovulation induction and age. Conclusions:Tubal pathology is associated risk of EP.
4.Study of PBL used in a new type of three phases labor trainee teaching
Chinese Journal of Medical Education Research 2015;(3):293-297
Objective To investigate whether the effect of PBL is better than LBL when used in a new type of three phases labor trainee teaching. Methods 216 medical students of the five-year and seven-year program who took part in labor trainee in the 2013-2014 school year were chosen and divided into two groups:PBL group and LBL group. Both the two groups' labor trainee were performed as three phases: trainee preparation, delivery room trainee, and discussion-class after trainee. Ques-tionnaire investigations were used to evaluate the effect of the delivery room trainee and discussion-class in PBL group and LBL group. A quiz after the third phase was used to examine whether the teaching effect of the two groups is different or not. Statistical analysis was performed using SPSS 16.0 software. Count data between sample rates were compared by chi square test, mean data between the two groups were compared by t test, the inspection level is α=0.05. Results Both in the delivery room trainee and discussion-class after trainee, questionnaire score in PBL group was significantly higher than that in LBL group (P<0.05). The average of quiz score in PBL group was 25.7±2.1, which was significantly higher than that in LBL group (19.3±3.6) (P<0.05). The excellent rate in PBL group was 82.6%, which was also higher than that in LBL group (P<0.05). Conclusion PBL teaching method elevates learning initiative of medical students and increases the teaching effect, and it can be promoted in labor trainee teaching.
5.Construction of care service quality evaluation indicator for elderly institution in Chongqing based on SERVQUAL Model
Chinese Journal of Practical Nursing 2014;30(21):15-19
Objective To set up care service quality evaluation indicators and establish weight coefficient for assessment of elderly institution in Chongqing.Methods SEVQUAL Model was used as the theoretical guidance,through Delphi expert inquiry,analytic hierarchy process (AHP),the weight of each indicator in five grades and consistency check was calculated.Results The care serv ice quality evaluation indicators contained five first-grade indexes and twenty second-grade indexes.The first-grade indexes included tangibles,reliability,responsiveness,assurance,empathy,respectively.The results of the consisten-cy check of the single grade sorts had a satisfying consistency(CR<0.10).Conclusions The scientific meth-ods and comprehensive indicators were applied to the construction of care service quality e-valuation indicators for elderly institution in Chongqing.In some degree,this construction of indicators may improve quality of care service and provide useful reference evidence for quality assessment in elderly in-stitution.
6.Challenges and opportunities for the development of Chinese traditional surgery
Journal of Integrative Medicine 2005;3(3):174-7
Chinese traditional surgery, an important branch of traditional Chinese medicine, has contributed greatly to the people's health in the history. With the fast development of modern medicine, Chinese traditional surgery is faced with serious challenges and its shortcomings have appeared more and more evident. In this article, the authors analyzed some problems in the development of Chinese traditional surgery and the opportunities for its further development, and suggested that the superiorities of Chinese traditional surgery should be enhanced in its future development.
7.The determination and clinical significance of endogenous vitamin C andvitamin E in patients with hypertension and stroke
Chinese Journal of cardiovascular Rehabilitation Medicine 2001;10(1):5-6
Objective: To study clinical significance of endogenous vitamin C 、 E in patients With hypertension and stroke. Methods: The serum vitamin C、 E, Malondialdehyde (MDA), superoxide dismutase (SOD) were determined by ultraviolet spectrophotometry in patients with hypertension (23 cases)、 hypertensive cerebral hemorrhage (CH, 30 cases)、 ischemic cerebrovascular disorders (IC, 25 cases) and control groups (20 cases). Results: Compared with control group, at acute stage of stroke, the Vit C、 E and SOD levels significantly reduced (P<0. 01), the MDA level significantly increased (P<0.01); at convalescent stage, the Vit C、 E gradually recover to normal, the SOD still reduced (P<0.05), the MDA still incresed (P<0.05). Conclusion: The endogenous Vit C、 E have significant change in patients with acute stage of stroke, it gradually recovers to normal in convalescent stage. Meanwhile the SOD and MDA change accordingly.
8.Expression of Wnt-β-catenin signaling pathway in kidney repair following ischemia reperfusion injury
Chinese Journal of Nephrology 2011;27(1):46-50
Objective To observe the change of Wnt-β-catenin signaling's location and expression in kidney repair after acute kidney injury induced by ischemla reperfusion (I/R).Methods Ischemia reperfusion injury in BAT-gal reportor mice was made and blood sample was taken from tails on the 1th day after injury. Mice were sacrified on the 2th or 7th day and kidneys and blood were collected. Renal pathological change was observed by PAS stain. The changes of location and expression of Wnt-β-catenin signaling were detected by immunofluorescence costainning X-gal-LTL, X-gal-NKCC2, X-gal-DBA respectively. The protein expressions of the Wnt4 and co-receptor Lrp6 were assessed by Western blotting. Results PAS-stained kidney sections showed desquamative or flattened epithelia, necrotic debris on day 2 and regenerating tubules on day 7. An injury-induced enhancement of the Wnt pathway response (X-gal staining) in kidney cortex and out-medulla. Immunolabelling of kidney sections from injured BAT-gal mice revealed that X-gal staining was detected in kidney epithelial cells (double-labelled with LTL or NKCC2). Western blotting showed the Wnt4 protein was up-regulated and phospho-Lrp6, indicative of active canonical Wnt signaling, was noted in kidney cortex from day 2 after I/R, but in control kidney cortex pLrp6 was not detected. Conclusion Wnt-β-catenin signaling is activited after acute kidney I/R injury and is required for tubular epithelial repair and regeneration following kidney I/R injury.
10.Progress in inhibitory mechanism of somatostatin in the growth of human colonic carcinoma cells
Chinese Journal of Clinical Pharmacology and Therapeutics 2004;0(12):-
Somatostatin(SS)is an inhibiting gut hor- mone that widely exists in central nervous system(CNS), gastrointestinal tract,pancreatic tissue.A lot of research- es indicate the anticancer activity of somatostatin ana- logue.It was reported to suppress proliferation of endo- crine tumors,especially some solid tumors in digestive system.This review summarizes the progress on mecha- nism of somatostatin analogue(SSTA)and its influences on colon cancer of in recent years.