1.Study on the proficiency testing program of pharmaceutical preparation analysis.
Lin-Bo WANG ; Mei-Cheng YANG ; Zhu-Kang CHEN ; Ming LU ; Pei-Jun ZHAI ; Gui-Liang CHEN ; Lin-Da WANG
Acta Pharmaceutica Sinica 2012;47(6):769-772
This proficiency testing program is established to evaluate the pharmaceutical preparation analysis capacity of laboratories recommended by 18 countries and economies. It was authorized by Asia Pacific Laboratory Accreditation Cooperation (APLAC), and organized by Shanghai Institute for Food and Drug Control (SIFDC) and China National Accreditation Service for Conformity Assessment (CNAS). The 0.3sigma test is used to evaluate the homogeneity and stability of the proficiency testing sample. The results of the laboratories were assessed by Z-score. The robust average and the robust standard deviation of the participants' results were calculated as assigned value and standard deviation for performance assessment of hydrochlorothiazide and captopril using robust statistics. Thirty-three of 38 laboratories recommended by 18 countries and economies sent their results back. Twenty-four laboratories' results were observed as satisfactory. Five laboratories were identified as having reported at least one questionable result. Four laboratories were identified as having reported at least one unsatisfactory result.
Accreditation
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Captopril
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analysis
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Drug Combinations
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Drug Stability
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Hydrochlorothiazide
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analysis
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Laboratory Proficiency Testing
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Pharmaceutical Preparations
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chemistry
2.Treatment of four cases of Fanconi anemia by allogeneic hematopoietic stem cell transplantation with low intensity conditional regimen.
Hui HOU ; Yan Hua YAO ; Jun LU ; Pei Fang XIAO ; Xin Ni BIAN ; Hu LIU ; Die Xin HU ; Jing LING ; Jie LI ; Zong ZHAI ; Ling Jun KONG ; Shao Yan HU
Chinese Journal of Hematology 2018;39(3):231-235
Objective: To evaluate the efficiency and safety of low intensity conditional regimen for children with Fanconi anemia (FA) receiving allogenic hematopoietic stem cells transplantation (allo-HSCT). Methods: Four patients diagnosed as Fanconi anemia were enrolled in this study. One patient received HLA-identical sibling donor hematopoietic stem cell transplantation, two patients underwent unrelated donor matched (UD) HSCT, and one patient received unrelated cord blood transplantation. The conditional regimen consisted of Busulfan with low dose of cyclophosphamide. Results: All 4 cases succeeded in allo-HSCT. The median time for neutrophils engraftment was 11(9-15) day, median time to platelets (PLT) engraftment was 12 (8-28) day. One case occurred with grade I of aGVHD, 1 case with hemorrhagic cystitis. No patient happened with hepatic veno-occlusive disease (VOD). Conclusion: Low intensity of conditional regimen is efficient and safe which should be recommended for FA patients with HSCT.
Busulfan
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Fanconi Anemia
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Graft vs Host Disease
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Hematopoietic Stem Cell Transplantation
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Humans
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Transplantation Conditioning
3.Auricular acupuncture and biomedical research--A promising Sino-Austrian research cooperation.
Pei-Jing RONG ; Jing-Jun ZHAO ; Yu-Qing LI ; Daniela LITSCHER ; Shao-yuan LI ; Ingrid GAISCHEK ; Xu ZHAI ; Lu WANG ; Man LUO ; Gerhard LITSCHER
Chinese journal of integrative medicine 2015;21(12):887-894
Treatment by auricular acupuncture has a long history. Ear-acupoint research has been advancing step by step in China and also in Europe. Auricles are rich in nerves, therefore a close relationship with different functions of the human body has been proved by the research teams of the two main authors of this article from China and Austria. In recent years, great progress has been made in the research of regulating human body functions through electroacupuncture at the auricular branch of the vagus nerve, which is part of auricular acupuncture therapy. It is well known that the auricular branch of the vagus nerve is the only peripheral pathway to the cerebral cortex. Studies of the Chinese team on hypertension, diabetes, epilepsy and depression have shown that the mechanism of auricular vagus nerve stimulation (VNS) may be comparable with cervical VNS in terms of pathways. Auricular VNS has a broad clinical application prospect.
Acupuncture, Ear
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Animals
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Austria
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Biomedical Research
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China
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Depression
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therapy
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Electric Stimulation Therapy
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Electroacupuncture
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Electroencephalography
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Epilepsy
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therapy
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Humans
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International Cooperation
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Reflex
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physiology
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Vagus Nerve
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physiology