Objective To analyse the clinical value of aspartate aminotransferase mitochondrial isoenzyme (m‐AST ) determina‐tion in patients with alcoholic liver disease .Methods 61 cases of patients with alcoholic liver disease (observe group) receiving treatment in this hospital from March 2013 to March 2015 and 61 cases of healthy individuals(control group) were enrolled in this study ,and serum levels of m‐AST ,alanine amino transferase(ALT) ,aspartate amino transferase(AST) and γ‐glutamyl transferase (GGT) were detected .Results Compared with the control group ,serum levels of of m‐AST ,ALT ,AST and GGT were increased in the observe group ,there were statistically significant differences (P<0 .05) .In patients with alcoholic liver disease ,after treatment , serum levels of m‐AST ,ALT ,AST and GGT were different among patients with hepatic adipose infiltration ,patients with hepatitis and patients with liver cirrhosis ,there were statistically significant differences(P<0 .05) .Conclusion Combined with ALT ,AST and GGT ,m‐AST could be utilized as an indicator for diagnosing alcoholic liver disease ,which has clinical significance .

Bone tissue engineering is the focus of recent research. Its status quo and tendency are discussed from scaffold, cell and tissue reconstruction. Based on this analysis, we want to shorten the distance before it's clinical application and give some reasonable methods.

Objective To explore the hyperthyroidism patients with Graves disease before and after treatment serum adiponectin level changes.Methods 108 cases of hyperthyroidism patients with Graves disease as the research object,they are divided into GD1 and GD2 two subgroups,and the other in the same period to our line of health inspection in 50 cases of healthy controls,fully explore hyperthyroidism before and after treatment in patients with Graves disease changes of the serum adiponectin level.Results Compared with healthy controls,GD1 group of adiponectin level is higher,the GD2 group of the low level of adiponectin,compared with those of GD2 group had significantly higher GD1 group,P<0.05.Data statistical differences between groups,P<0.05.GD group of TSH is lower than healthy controls,GD1 TSH level below the GD2 group.P<0.05,compared with healthy controls,GD two subgroups of FT3 level was significantly higher,data statistical differences between groups,P<0.05,compared with those of GD2 group GD1 group of FT3 level is higher,data statistical differences between groups,P<0.05 compared with control group,GD1 group had a significantly higher FT4 levels,P<0.05.GD2 group FT4 level slightly lower than the control group,P>0.05,compared with those of GD2 group GD1 group had a significantly higher FT4 levels,P<0.05.The control group,the GD1 and GD2 group of serum adiponectin level and TSH is negative correlation,and FT4,FT3 is positive correlation,and there is no correlation between the baseline data.Conclusion Graves disease hyperthyroidism in treatment,adiponectin levels rise,after drug treatment,obtain relief,adiponectin increase cholesterol and FT4 influence,and the correlation between glucose metabolism index is not strong.After treatment,Graves disease in patients with hyperthyroidism adiponectin level is lower than normal group,the low and FT4 levels after treatment with a certain relevance.

Objective To investigate the promoting effect of acupuncture plus massotherapy on post-lithotripsy stone discharging in urinary stone patients.Methods Sixty-two patients who had received extracorporeal shock wave lithotripsy were randomly allocated to treatment and control groups, 31 cases each. The treatment group received acupuncture plus massotherapy and the control group, no treatment. The incidence of postoperative complications was observed in the two groups. The clinical therapeutic effects were compared between the two groups.Results The total efficacy rate and the incidence of postoperative complication were 90.3% and 61.3%, respectively, in the treatment group and 77.4% and 80.6%, respectively, in the control group. There were statistically significant differences between the two groups (P<0.01).Conclusion Acupuncture plus massotherapy can promote post-lithotripsy stone dis- chargeing in urinary stone patients.

ObjectiveTo investigate the delayed umbilical cord clamping in preterm children of anemia in premature children.Methods60 preterm children were randomly divided into study group and control group 30 patients in each group.The control group was taken regular off umbilical,the observation group delay 90s(after birth at least 2min) off umbilical.ResultsThe Hb, HCT, and SI in the postnatal 1,2,4,8 weeks were significantly lower than the observation group, the difference was statistically significant (all P ＜ 0.05), and the control group after birth in preterm children Ret in the first week was significantly higher than 2,4 in the observation group, the difference was statistically significant(all P ＜ 0.05) ; The observation group at 6 months the incidence of anemia(13.3％) and transfusion rate(6.7％) were significantly lower than the control group(43.3％ ,33.3％) ,the difference was statistically significant(all P ＜0.01).ConclusionDelyed umbilical cord clamping in preterm children could increase the redblood cells and iron reserves in preterm children, reduce the incidence of anemia caused by blood transfusion, was worthy of clinical application.

AlM: To evaluate the clinical effect of implantation of phakic anterior chamber iris clip intraocular lens in high myopia patients.
METHODS: Fifty eyes of 28 high myopia patients with anterior chamber phakic Verisyse iris clip intraocular lens implantation were observed. The visual acuity, best corrected visual acuity, intraocular pressure, corneal and anterior chamber inflammation changes were observed after the procedure.
RESULTS: Fifty eyes of 28 high myopia patients were successfully accepted implantation of phakic anterior chamber iris clip intraocular lens. Visual acuity of all the patients was increased after operation. And one year later, visual acuity of 38 eyes ( 76%) ≥1. 0, 12 eyes (24%) ≥0. 5, best corrected visual acuity of 40 eyes (80%) ≥1. 0, 10 eyes ( 20%) ≥0. 5. ln 22 eyes, the postoperative best corrected visual acuity were reached and exceeded preoperative best corrected visual acuity.CONCLUSlON: lmplantation of iris clip intraocular lens in high myopia patients with anterior chamber lens was feasibility and effective.

Thyroid associated ophthalmopathy (TAO) is often shown as upper eyelid retraction,conjunctival hyperemia and edema,proptosis,diplopia,strabismus and decreased visual acuity.It is difficult to make a certain diagnosis in the early stage of TAO.Patients suffering from TAO often have upper eyelid retraction at the early stage of disease,which affects appearance and causes feelings of discomfort and decreased visual acuity.Learning more about upper eyelid retraction contributes to the early diagnosis and treatment of TAO.Although upper eyelid retraction with TAO has distinctive manifestations,it is easy to misdiagnose.The differential diagnosis includes congenital eyelid retraction,neurological disorders,high axial myopia,glaucoma filtering bleb,and so on.Family history,clinical manifestations and TAO related examinations should also be taken into consideration.Comprehensive treatments should be adopted.Glucocorticoids and eyelid retraction surgeries are current mainstay of treatment.There are controversies on the application of glucocorticoids about the specific dosage,while agreement achieved that the cumulative dose should not be more than 8 g in one stage in order to reduce the risk of liver failure and other adverse events.Different operation methods should be chosen according to the degrees of retraction and causes of disease for each type of patients.In addition,special attentions should be paid to the decrease of muscle strength in the temporal side.Individual analysis is needed in order to diagnose and treat upper eyelid retraction with TAO.Early diagnosis and intervention can improve the appearance,visual function and quality of life of the patients.

Lipoxins possess a wide spectrum of adjustment function for various inflammatory cell functioning and the expression of inflammatory related genes,also progressing the inflammatory response by means of various cell.Lipoxins play an important role in the pathogenesis and clinical treatment of kidney diseases.