No abstract available.
Delivery of Health Care ; History, 20th Century ; Biography (publication types) ; Hospitals, University ; Pediatrics

Kienbock's disease is very rare in pediatrics. The treatment of Kienbock's disease is controversial and depends on an understanding of the natural history of the disease. The methods proposed vary from conservative treatment to surgical treatment such as radial shortening or scaphotrapezoidal joint fixation, but there are few therapeutic guidelines for paediatric Kienbock's disease. We encountered a 14-year-old male with Lichtman stage IIIB disease and treated him with conservative management. We report this rare case of advanced paediatric Kienbock's disease with good clinical results at the 2-year follow-up along with a review of the relevant literature.
Adolescent ; Follow-Up Studies ; Humans ; Joints ; Male ; Natural History ; Osteonecrosis* ; Pediatrics

Harlequin syndrome, which is a rare disorder caused by dysfunction of the autonomic system, manifests as asymmetric facial flushing and sweating in response to heat, exercise, or emotional factors. The syndrome may be primary (idiopathic) with a benign course, or can occur secondary to structural abnormalities or iatrogenic factors. The precise mechanism underlying idiopathic harlequin syndrome remains unclear. Here, we describe a case of a 6-year-old boy who reported left hemifacial flushing and sweating after exercise. He had an unremarkable birth history and no significant medical history. Complete ophthalmological and neurological examinations were performed, and no other abnormalities were identified. Magnetic resonance imaging was performed to exclude lesions of the cerebrum and cervicothoracic spinal cord, and no abnormalities were noted. His final diagnosis was classic idiopathic harlequin syndrome. Herein, we report the first pediatric case of idiopathic harlequin syndrome in Korea.
Cerebrum ; Child ; Diagnosis ; Flushing ; Hot Temperature ; Humans ; Korea ; Magnetic Resonance Imaging ; Male ; Neurologic Examination ; Pediatrics ; Reproductive History ; Spinal Cord ; Sweat ; Sweating

Child ; China ; Endocrinology ; history ; History, 20th Century ; History, 21st Century ; Humans ; Pediatrics ; history

Child ; History, 20th Century ; History, 21st Century ; Humans ; Pediatrics ; history ; Pharmacology, Clinical ; history ; Societies, Medical ; history

Child ; Gastroenterology ; history ; History, 20th Century ; History, 21st Century ; Humans ; Pediatrics ; history ; Societies, Medical ; history

Child ; Hematology ; history ; History, 20th Century ; History, 21st Century ; Humans ; Pediatrics ; history ; Societies, Medical ; history

Child ; History, 20th Century ; History, 21st Century ; Humans ; Nephrology ; history ; Pediatrics ; history ; Societies, Medical ; history

PURPOSE: The spontaneous seroconversion rate of hepatitis B e antigen (HBeAg)-positive chronic hepatitis B (CHB) virus infection in children is lower than that in adults. However, few studies have investigated the rate of transition from the immune-tolerant to the early immune-clearance phase in children. METHODS: From February 2000 to August 2011, we enrolled 133 children aged <18 years who had visited the Department of Pediatrics, Kyungpook National University Hospital. All subjects were in the immune-tolerant phase of HBeAg-positive CHB virus infection. The estimated transition rate into the early immune-clearance phase was calculated using the Kaplan-Meier method. RESULTS: Among the 133 enrolled pediatric CHB virus infection patients in the HBeAg-positive immune-tolerant phase, only 21 children (15.8%) had converted to the early immune-clearance phase. The average age at entry into active hepatitis was 10.6+/-4.8 years. The incidence of transition from the immune-tolerant to the early immune-clearance phase in these children was 1.7 episodes/100 patient-years. When analyzed by age, the estimated transition rate was 4.6%, 7.1%, and 28.0% for patients aged <6, 6-12, >12 years, respectively. CONCLUSION: In children with CHB virus infection, the estimated rate of entry into the early immune-clearance phase was 28.0% for patients aged 12-18 years, which was significantly higher than that observed for children aged <12 years (11.7%; p=0.001).
Adult ; Child* ; Gyeongsangbuk-do ; Hepatitis ; Hepatitis B ; Hepatitis B virus ; Hepatitis B, Chronic* ; Hepatitis, Chronic* ; Humans ; Incidence ; Natural History ; Pediatrics ; Phase Transition

Behavioral Medicine ; Child ; Child Behavior ; Child Behavior Disorders ; diagnosis ; prevention & control ; psychology ; Child Development ; Child Health Services ; trends ; China ; Developmental Disabilities ; diagnosis ; prevention & control ; History, 20th Century ; History, 21st Century ; Humans ; Pediatrics ; history ; trends ; Prospective Studies ; Psychology, Child