1.Clinical presentation and surgical outcomes of congenital divided nevus of the eyelids in three Filipino patients: A case series
Mayleen D. Jereza ; Alexander D. Tan ; Armida L. Suller-pansacola ; Charisse Ann S. Tanlapco ; Patrick S. Quezon ; Yasser E. Alhasan ; Mark Niñ ; o A. Estrella ; Jann Perrie S. Alipio
Acta Medica Philippina 2025;59(Early Access 2025):1-10
Congenital divided nevus of the eyelids is a rare form of melanocytic nevus which involves contiguous portions of the upper and lower eyelid margins unilaterally, hence the term ‘kissing nevus’. While usually present at birth, these nevi may also appear later in life. When the mass enlarges, it may cause cosmetic issues to the patient, as well as functional problems such as mechanical ptosis, ectropion, and epiphora.
We report three cases of congenital divided nevus of the eyelids, all presenting with unilateral upper and lower hyperpigmented lid masses since birth. The first case had an upper lid mass measuring 11 mm x 19 mm, and a lower lid mass measuring 55 mm x 47 mm, with both masses extending into the palpebral conjunctiva, and causing severe ptosis and corneal neovascularization due to chronic irritation. The second case presented with hyperpigmented masses at the lateral third of the right upper eyelid measuring 8 mm x 17 mm and of the lower eyelid measuring 9 mm x 15 mm on the lower lid with lashes growing through the masses. There was extension of the mass into the palpebral conjunctiva. The third case presented with a 23 x 18 mm hyperpigmented, well-circumscribed, verrucated mass at the medial half of the upper eyelid crossing the eyelid margin, and a 15 x 13 mm lesion at the medial third of the lower lid with the same characteristics, with small crusty lesions and clotted blood. All three patients underwent excision biopsy with lid reconstruction using full thickness skin grafts from the supraclavicular area. Six months postoperatively, the first case underwent a repeat full thickness skin graft due to graft contraction, and also received two sessions of fractional carbon dioxide (CO2 ) laser, two sessions of intralesional triamcinolone injections, and silicone gel application with further improvement of graft healing and scarring. The second case also underwent two sessions of intralesional steroid injection for scar management. During follow-up, which spanned 13 months for the first case, 10 months for the second case, and two months for the third case, improved functional and cosmetic outcomes were observed.
This case series highlights the outcomes of the most common surgical technique done for congenital divided nevi of the eyelids. Congenital divided nevi are usually diagnosed clinically and malignant degeneration is rare, hence lid reconstruction may be done without frozen section. The cases in the series were treated due to cosmetic and functional purposes, hence the importance of continuous post-operative follow-up to monitor for graft dehiscence, scar development, recurrence of the mass, malignant degeneration, and development of lid malposition. Additional procedures for scar management, such as CO2 laser and intralesional steroid injections, may be necessary to further enhance outcomes in complex cases. All three cases in this series exhibited improved functional and cosmetic outcomes post-operatively, with significant reduction in ptosis and scarring. Longterm follow-up revealed satisfactory recovery with minimal complications, with no recurrence nor malignant degeneration.
Human ; Male ; Female ; Adult: 25-44 Yrs Old ; Young Adult: 19-24 Yrs Old ; Nevus ; Nevus, Pigmented
2.Association between knowledge and actual practices of family member caregivers of lowincome families on the prevention and control of soil-transmitted helminthiasis in an urban barangay: An analytical cross-sectional study
Maria Eliza S. Pascual ; Thereese Maeann C. Patron ; Rydni B. Pastor ; Maria Francel Charlyn N. Tan ; Ranee Coeline B. Tongco ; Josel R. Tanciongco ; Patrick Joshua C. Pascual ; Januario E. Sia-Cunco ; Ramon Jason M. Javier
Health Sciences Journal 2024;13(1):31-37
Introduction:
Soil-transmitted helminthiasis (STH) remains to be highly prevalent in the Philippines,
despite the implementation of school-based bi-annual mass drug administration and other preventive
measures under the Garantisadong Pambata Program by the Department of Health (DOH).
Methods:
This analytical cross-sectional study determined the association between the level of knowledge
and the actual practices of family care givers in the prevention of STH among school-age children belonging
to low-income families in an urban barangay.
Results:
Among 193 respondents, 97.93% had good level of knowledge of STH prevention and control, 83.42%
had good hand hygiene practices, but only 39.90% adhered to the recommended bi-annual anti-helminthic
prophylaxis for their school-aged children. A positive association was noted between level of knowledge
and actual hand hygiene practices, but this was not statistically significant (i.e., prevalence odds ratio
= 5.3, p = 0.129). Among those who did not comply with the bi-annual anti-helminthic administration,
there was a prevalence odds ratio (POR) of 0.66 that the family care giver was knowledgeable on STH
prevention and control, and this negative association was not statistically significant (i.e., p = 0.529).
Conclusion
Level of knowledge on STH prevention was positively associated with hand hygiene practices
but was negatively associated with compliance with the bi-annual deworming prophylaxis. But these
associations were not statistically significant.
Hand Hygiene
3.Establishing a national indicator-based surveillance system for hospital bed utilization by COVID-19 patients in the Philippines
Bienvenido S Cabaro III ; Gabrielle Ann T Dela Paz ; Jeffrey B Dotingco ; Bernadette Joy Q Almirol ; Gabriel R Borlongan ; Reena Ophelia D Cebreros ; Patrick B Diangco ; Kenneth Pierre B Quijalvo ; Joanne Pauline U Tan ; Ramon Rafael D Tonato
Western Pacific Surveillance and Response 2023;14(5):33-39
In March 2020, the Philippine Department of Health (DOH) designed and rapidly implemented a national surveillance system for the utilization of hospital beds by patients with coronavirus disease (COVID-19) to produce complete and timely data for use by various levels of governance in response to the COVID-19 pandemic. The DOH launched the DOH DataCollect (DDC) Bed Tracker system, a web-based application that collects information from all 1906 public and private hospitals and infirmaries across the country using a modular data collection tool. Data on the maximum number of occupied COVID-19-designated beds (n = 28 261), hospital bed utilization rate (71.7%), and mechanical ventilator number (n = 1846) and utilization rate (58.5%) were recorded in September 2021 during the Delta surge of cases in the Philippines. Data on human resources, personal protective equipment and supplies, and other operational indicators were added to the system during various modifications. Information from the DDC was used to inform the COVID-19 response and operations at national and local levels and facilitated research at academic and nongovernmental agencies. The development of the DDC system demonstrates that an effective surveillance system for use by all health-care facilities is achievable through strong national leadership, the use of available technology and adaptive information systems, and the establishment of networks across different health facilities and stakeholders.
4.The University of Santo Tomas Hospital (USTH) 2022 Institutional Chest Pain Pathway: Approach to diagnosis, risk stratification, and management.
Jannah Lee TARRANZA ; Christine Joy BONGON ; Maria Monica VALDEZ ; John Paul TIOPIANCO ; Alexander REYES ; John Patrick ONA ; Don Robespierre REYES ; Marcellus Francis RAMIREZ ; Aileen Cynthia DE LARA ; Clarissa MENDOZA ; Wilson Tan DE GUZMAN ; Zacarias MANUEL ; Eduardo S. CAGUIOA ; Milagros YAMAMOTO
Journal of Medicine University of Santo Tomas 2022;6(S1):11-24
This clinical pathway for the diagnosis and risk stratification of patients presenting with acute chest pain, including acute coronary syndromes, provides recommendations and algorithms for clinicians to diagnose, risk stratify, and manage acute chest pain in adult patients. The writing committee reviewed existing international and local guidelines. Modifications to the algorithm following face-to-face and virtual meetings resulted in expert decisions written as recommendations and presented in a flow diagram format. The USTH Chest Pain Pathway provides guidance based on current guidelines and recommendations on assessing and evaluating acute chest pain, tailored to local needs and institution-specific facilities. We recommend its use to ensure quality patient care in the hospital.
Acute Coronary Syndrome|critical Pathways
6.Accuracy of Thoracolumbar Pedicle Screw Insertion Based on Routine Use of Intraoperative Imaging and Navigation
Pirateb Paramasivam Meenakshi SUNDARAM ; Jacob Yoong-Leong OH ; Mark TAN ; Colum Patrick NOLAN ; Chun Sing YU ; Ji Min LING
Asian Spine Journal 2021;15(4):491-497
Retrospective review. To determine the accuracy of thoracolumbar pedicle screw insertion with the routine use of three-dimensional (3D) intraoperative imaging and navigation over a large series of screws in an Asian population. The use of 3D intraoperative imaging and navigation in spinal surgery is aimed at improving the accuracy of pedicle screw insertion. This study analyzed 2,240 pedicle screws inserted with the routine use of intraoperative navigation. It is one of very few studies done on an Asian population with a large series of screws. Patients who had undergone thoracolumbar pedicle screws insertion using intraoperative imaging and navigation between 2009 and 2017 were retrospectively analyzed. Computed tomography (CT) images acquired after the insertion of pedicle screws were analyzed for breach of the pedicle wall. The pedicle screw breaches were graded according to the Gertzbein classification. The breach rate and revision rate were subsequently calculated. A total of 2,240 thoracolumbar pedicle screws inserted under the guidance of intraoperative navigation were analyzed, and the accuracy of the insertion was 97.41%. The overall breach rate was 2.59%, the major breach rate was 0.94%, and the intraoperative screw revision rate was 0.7%. There was no incidence of return to the operating theater for revision of screws. The routine use of 3D navigation and intraoperative CT imaging resulted in consistently accurate pedicle screw placement. This improved the safety of spinal instrumentation and helped in avoiding revision surgery for malpositioned screws.
7.The therapeutic dilemma of idiopathic granulomatous mastitis.
Ee Ling Serene TANG ; Chi Shern Bernard HO ; Patrick Mun Yew CHAN ; Juliana Jia Chuan CHEN ; Mui Heng GOH ; Ern Yu TAN
Annals of the Academy of Medicine, Singapore 2021;50(8):598-605
INTRODUCTION:
Idiopathic granulomatous mastitis (IGM) is a rare, benign, chronic breast condition that can cause repeated abscesses or mass formation in bilateral breasts. The condition can severely impact the quality of life of affected women. This study aims to evaluate effective treatment modalities, as well as understand the demographics and clinical presentation of patients with IGM.
METHODS:
An 11-year retrospective review was performed of patients diagnosed with IGM from 1 January 2008 to 31 December 2018 at a tertiary breast unit.
RESULTS:
A total of 77 patients were included in the study. The median age at presentation was 36 years old. IGM presented most commonly as a breast lump (98.1%). The median number of flares was 2 (1-12). Of the 77 patients, 68.8% (53) were treated with antibiotics, 50.6% (39) with steroids, and 44.2% (34) underwent surgery, in the course of their IGM treatment. Forty-five (59.2%) of the 76 patients with IGM required a multimodal treatment approach to achieve remission. There was no significant difference in the number of flares no matter the initial treatment (
CONCLUSION
IGM is a clinical diagnosis. It is a rare, relapsing breast inflammatory condition that affects young females with no superior treatment modality. Smoking is associated with higher number of flares of IGM and should be discouraged in IGM patients.
Adult
;
Anti-Bacterial Agents/therapeutic use*
;
Female
;
Granulomatous Mastitis/therapy*
;
Humans
;
Quality of Life
;
Retrospective Studies
;
Treatment Outcome
8.Accuracy of Thoracolumbar Pedicle Screw Insertion Based on Routine Use of Intraoperative Imaging and Navigation
Pirateb Paramasivam Meenakshi SUNDARAM ; Jacob Yoong-Leong OH ; Mark TAN ; Colum Patrick NOLAN ; Chun Sing YU ; Ji Min LING
Asian Spine Journal 2021;15(4):491-497
Retrospective review. To determine the accuracy of thoracolumbar pedicle screw insertion with the routine use of three-dimensional (3D) intraoperative imaging and navigation over a large series of screws in an Asian population. The use of 3D intraoperative imaging and navigation in spinal surgery is aimed at improving the accuracy of pedicle screw insertion. This study analyzed 2,240 pedicle screws inserted with the routine use of intraoperative navigation. It is one of very few studies done on an Asian population with a large series of screws. Patients who had undergone thoracolumbar pedicle screws insertion using intraoperative imaging and navigation between 2009 and 2017 were retrospectively analyzed. Computed tomography (CT) images acquired after the insertion of pedicle screws were analyzed for breach of the pedicle wall. The pedicle screw breaches were graded according to the Gertzbein classification. The breach rate and revision rate were subsequently calculated. A total of 2,240 thoracolumbar pedicle screws inserted under the guidance of intraoperative navigation were analyzed, and the accuracy of the insertion was 97.41%. The overall breach rate was 2.59%, the major breach rate was 0.94%, and the intraoperative screw revision rate was 0.7%. There was no incidence of return to the operating theater for revision of screws. The routine use of 3D navigation and intraoperative CT imaging resulted in consistently accurate pedicle screw placement. This improved the safety of spinal instrumentation and helped in avoiding revision surgery for malpositioned screws.
9.A Prospective Audit of Airway Code Activations and Adverse Events in Two Tertiary Hospitals.
Yuen Mei CHOW ; Zihui TAN ; Chai Rick SOH ; Shimin ONG ; Jinbin ZHANG ; Hao YING ; Patrick WONG
Annals of the Academy of Medicine, Singapore 2020;49(11):876-884
INTRODUCTION:
Airway management outside the operating room can be challenging, with an increased risk of difficult intubation, failed intubation and complications. We aim to examine airway practices, incidence of difficult airway and complications associated with airway code (AC) activation.
METHODS:
We conducted a prospective audit of AC activations and adverse events in two tertiary hospitals in Singapore. We included all adult patients outside the operating room who underwent emergency intubation by the AC team after AC activation. Adult patients who underwent emergency intubation without AC activation or before the arrival of the AC team were excluded. Data were collected and documented by the attending anaesthetists in a standardised survey form shortly after their responsibilities were completed.
RESULTS:
The audit was conducted over a 20-month period from July 2016 to March 2018, during which a total of 224 airway activations occurred. Intubation was successful in 218 of 224 AC activations, giving a success rate of 97.3%. Overall, 48 patients (21.4%) suffered an adverse event. Thirteen patients (5.8%) had complications when intubation was carried out by the AC team compared with 35 (21.5%) by the non-AC team.
CONCLUSION
Dedicated AC team offers better success rate for emergency tracheal intubation. Non-AC team attempted intubation in the majority of the cases before the arrival of the AC team. Increased intubation attempts are associated with increased incidence of adverse events. Equipment and patient factors also contributed to the adverse events. A multidisciplinary programme including the use of supraglottic devices may be helpful to improve the rate of success and minimise complications.
10.Understanding the Psychosocial Needs of Women who Present with Advanced Breast Cancer.
Ee Ling Serene TANG ; Pei Yi SIN ; Juliana Jia Chuan CHEN ; Mun Yew Patrick CHAN ; Melanie Dee Wern SEAH ; Sarah Qinghui LU ; Mui Heng GOH ; Ern Yu TAN
Annals of the Academy of Medicine, Singapore 2020;49(12):990-995
INTRODUCTION:
Advanced breast cancer (ABC) remains common in Singapore. In 2019, 22.1% of breast cancer patients presented with ABC in our institution. Despite increasing affluence and the advent of national mammographic screening, the incidence of ABC has not changed significantly. This suggests inherent differences in women who present late. We aim to explore the socio-economic background, knowledge and attitudes of women who present with ABC.
METHODS:
Between December 2013 and July 2015, 100 patients who presented consecutively with ABC in a tertiary institution in Singapore were recruited to participate in an interviewer-led questionnaire exploring psychosocial and economic issues.
RESULTS:
Among the 100 patients, 63 and 37 presented with stages 3 and 4 breast cancer respectively. Median age was 57 (27-86), 52% had at least secondary education, 53% had no formal employment and 71% were married; 88% were aware of breast cancer symptoms, 82% were aware that mammography can help detect cancer, 82% believed that current treatment modality for breast cancer is effective, 96% had never undergone a mammography and 52.9% felt mammograms were unnecessary. A total of 64% presented symptomatic from the breast tumour, with a median duration of 3 months. Many of the patients were aware of breast cancer symptoms and the utility of mammography. However, a group of patients did not comply with screening. This may be due to poor understanding about breast screening and detection in its asymptomatic phase.
CONCLUSION
Further public education to improve understanding of breast cancer and screening mammography may help to improve rates for earlier detection of breast cancer.


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