1.Glomus Tumour: A Retrospective Review of 15 Years Experience in A Single Institution
Rashdeen Fazwi ; Patricia Ann Chandran ; T Sara Ahmad
Malaysian Orthopaedic Journal 2011;5(3):8-12
Glomus tumours (GT), neoplasms of the glomus body
comprise 4.5% of upper limb tumours. Seventy-five per cent
of these occur in the hand, and most are subungual (50%).
We performed a literature review and retrospective search of histopathologically confirmed GT seen from 1995 to 2009.
Fifteen patients were identified, with an average age of 49.6 years. Eight were in the hand, 2 in the upper limb, 2 lower limb and 3 in the ear. Eighty-six per cent presented with pain and 50% underwent radiological investigation. Most diagnoses followed biopsy findings. Surgical excision
resulted in a recurrence rate of 13%. The average time to
diagnosis was 3.3 years. The average duration of symptoms
was 7 to 11 years with an average of 2 to 3 consultations prediagnosis. MRI remains the most useful imaging modality
(82 to 90% sensitivity). Excision biopsy is the most common
treatment. Greater awareness is needed for quicker
diagnosis.
2.Microfilaria in hydrocele fluid cytology.
Patricia Ann Chandran ; Gita Jayaram ; Rohela Mahmud ; A Khairul Anuar
The Malaysian journal of pathology 2004;26(2):119-23
Filariasis, a parasitic infection endemic in parts of India, Myanmar, islands of the South Pacific, West and East Africa and Saudi Arabia can be diagnosed from various types of cytopathological specimens. This case documents the detection of filarial infection from hydrocele fluid cytology in a 30-year-old Myanmar migrant worker in Malaysia.
Liquid substance
;
Cellular aspects of
;
Infection as complication of medical care
;
Microfilaria
;
Myanmar
3.Lymphocytic Mastitis Mimicking Breast Carcinoma, Radiology and Pathology Correlation: Review of Two Cases
Sharifah Majedah Idrus Alhabshi ; Kartini Rahmat ; Caroline Judy Westerhout ; Nani Harlina Md Latar ; Patricia Ann Chandran ; Suraya Aziz
Malaysian Journal of Medical Sciences 2013;20(3):83-87
Lymphocytic mastitis, or diabetic mastopathy, is an unusual finding in early-onset and long-standing diabetes. It can presents as a non-tender or tender palpable breast mass. Mammogram and ultrasound frequently demonstrate findings suspicious of malignancy, thus biopsy and histological confirmation is usually required. We reviewed two cases of lymphocytic mastitis with characteristics findings on mammogram, ultrasound, and histopathology. Diagnoses were confirmed with excision biopsy.
Breast Neoplasms
;
Diabetes Mellitus
4.Synchronous unilateral infiltrating ductal and lobular breast carcinoma.
Shaleen KAUR ; Kartini RAHMAT ; Patricia Ann CHANDRAN ; Kasumawati ALLI ; Yang Faridah Abdul AZIZ
Singapore medical journal 2012;53(11):e240-3
The incidence of synchronous bilateral infiltrating breast cancer has been reported to be 2%. However, synchronous unilateral infiltrating ductal carcinoma and infiltrating lobular carcinoma (ILC) are very rarely reported. We present a woman with palpable ILC who was later found to have synchronous well-circumscribed ductal carcinoma on further imaging. We also discuss the use of diagnostic approaches such as ultrasonography, mammography and histopathology. This case highlights the importance of careful assessment of concurrent lesions in the breast in the presence of an existing carcinoma.
Breast Neoplasms
;
complications
;
diagnosis
;
Carcinoma, Ductal, Breast
;
complications
;
diagnosis
;
Carcinoma, Lobular
;
complications
;
diagnosis
;
Female
;
Humans
;
Mammography
;
Middle Aged
;
Neoplasms, Second Primary
;
diagnosis
5.Progressive multifocal leukoencephalopathy limited to the posterior fossa
Kartini Rahmat ; Shaleen Kaur ; Norlisah Mohd Ramli ; Patricia Ann Chandran ; Kum-Thong Wong ; Suhailah Abdullah ; Sharifah S Omar ; Dharmendra Ganesan ; Chong-Tin Tan
Neurology Asia 2010;15(3):283-286
Progressive multifocal leukoencephalopathy (PML) is a rapidly progressive demyelinating disease
caused by the reactivation of JC papova virus usually in immunocompromised hosts.1
The disease is
a chronic viral infection resulting in mortality within a year.2
The condition characterized by white
matter changes in multiple locations of the brain is caused by destruction of the oligodendrogliocytes.2
We report a case of AIDS associated PML presenting with progressive cerebellar symptoms, with the
unusual feature of imaging abnormalities limited to the posterior fossa.