Adult ; Aged ; Antifungal Agents ; administration & dosage ; adverse effects ; classification ; Candida ; drug effects ; isolation & purification ; Carcinoma ; pathology ; therapy ; Cross Infection ; microbiology ; therapy ; Drug Resistance, Multiple, Fungal ; Female ; Fractures, Bone ; surgery ; Humans ; Male ; Middle Aged ; Mycoses ; microbiology ; therapy ; Patient Care Management ; methods ; Pulmonary Disease, Chronic Obstructive ; complications ; therapy ; Surgical Wound Infection ; microbiology ; therapy ; Symptom Flare Up ; Treatment Outcome

Background: Surgical site infection (SSI) poses a serious threat in Neurosurgery. The mere presence of SSI would warrant a prompt medical and/ or surgical intervention for the outcome is very poor. This study aims to establish whether a pre-operative hospital stay of >7 days & other risk factors predisposes to surgical site infections. Methods: Retrospective, cross-sectional study of all pediatric patients who underwent clean neurosurgical procedures for the first time from January 1, 2011- June 30, 2014, in the Philippine General Hospital. The primary outcome was the development of a surgical site infection within 30 days from spine surgery or 90 days from intracranial surgery. Univariate and multivariate logistic regression analyses were performed to show the association of demographic and clinical factors with the development of SSI. Results: 279 medical charts were available for review. Median age was 1 year(5 days to 18 years old). The overall prevalence rate of SSI was 11.26%. Patients with >7 days pre-operative hospital stay had an incidence rate for SSI of 76.47% compared to 23.53% in patients with <7 days pre-operative hospital stay (OR 1.61, CI 0.68-3.84, p=0.280). Conclusions The incidence of SSI is high compared to other centers. There was no association of preoperative hospital stay with SSI. The association was significant only for the history of nosocomial infection. Early pre-operative clearance and surgery are recommended. Further prospective studies and surveillance are warranted
Surgical Wound Infection ; Cross Infection

The study retrospectively reviewed 1,029 general surgery operations performed from September 1, 1991 to May 31, 1993 to find out the association between the occurrence of surgical site infection (SSI) and the Centers for Disease Control-National Nosocomial Infection Surveillance (CDC-AWS) surgical patient risk index scores. The index assigned 1 point for each of 3 risk factors: 1) American Society of Anesthesiologists (ASA) preoperative assessment class 3, 4 or 5; 2) an operational classified as either contaminated or dirty-infected; 3) an operation with a duration longer than a specified increased with increasing contamination (p=0.000) as well as increasing index scores (p=0.000). Looking at operations within the same category of contamination, SSI rates also increased with increasing scores among clean operations (p=0.944), clean-contaminated operations (p=0.000), contaminated operations (p=0.559), and dirty operations. SSI rates in this hospital series were compared to the 44-hospital CDC-NNIS report.

Human ; Male ; Female ; Surgical Wound Infection ; Cross Infection ; Anesthesiologists

Background: Healthcare-associated infections (HAIs) among patients in surgical wards are serious complications that do not only affect surgical outcomes, but also increase medical care costs. Objective: To determine the proportion of patients with HAIs in surgery wards and identify factors associated with HAIs. Design: Cross-sectional study. Setting: Department of Surgery, Southern Philippines Medical Center, from January 2016 to December 2016. Participants: 182 patients from different surgical wards. Main outcome measures: Presence of HAI; prevalence odds ratios (POR) of having an HAI for selected factors. Main results: There were 182 patients (122 males and 62 females; mean age 34.89 ± 20.56 years) included in this report. Seventeen patients (9.34%) developed HAI during admission. Among patients who underwent surgery (n=126), having an HAI was significantly associated with: operation time >180 minutes (adjusted POR=15.18; 95% CI 3.92 to 58.69; p=0.0001), >4 surgical team members (adjusted POR=5.42; 95% CI 1.37 to 21.41; p=0.0158), general anesthesia (adjusted POR=10.46; 95% CI 1.29 to 84.63; p=0.0278), and use of inhalational anesthesia (adjusted POR=11.81; 95% CI 1.45 to 96.08; p=0.0210). Conclusion In this study, 9.34% of patients had an HAI during admission. Long hospital stay, use of indwelling medical devices, long surgical procedures, high number of surgical team members during surgery, general anesthesia, and use of inhalational anesthesia are all associated with having an HAI.
Surgical Wound Infection ; Cross Infection ; Pneumonia ; Anesthesia, General

In search of the best preventive measures against postoperative wound infections, the author has conducted a series of studies which preliminary results are as follows. (1) There were no postoperative secondary infections in 50 surgical cases except in one, which had undergone dacryocystorhinostomy. (2) More than one strain of microorganism were isolated from all of 20 operator's nostril, throat, and peritonsillar region. It is strongly suggested that operators and hospital workers play an important role in the cause of hospital infection. (3) Some difference in the strain of organisms isolated were noted between the countrymen and townsmen. (4) It is urged to pay particular attention to sterilization for lowere abdominal surgery. (5) Chloramphenicol exerted an sustained and excellent broadspectrum antimicrobial activity to various microorganisms.
Chloramphenicol ; Coinfection ; Cross Infection ; Dacryocystorhinostomy ; Pharynx ; Sterilization ; Surgical Wound Infection ; Wound Infection* ; Wounds and Injuries*

PURPOSE: This study was undertaken to find two things. One was to reveal the infection route of methicillin resistant Staphylococcus aureus(MRSA) that causes serious nosocomial infection through epidemic study, and the other was to seek preventative methods through blocking the dispersion. MATERIALS AND METHODS: We cultured MRSA obtained by nasal cavity swabbing, from 82 doctors and 219 personnel in our hospital, between September 1997 and August 1999. In addition, swabs were taken from the nasal cavities and surgical sites of 57 orthopaedic surgery patients, who were free of wound infection. In this practice, we use the disc test for drug sensitivity, and pulse-field gel electrophoresis (PFGE) to separate colonies. RESULTS: MRSA was discovered in 8 doctors (10%) and in 13 personnels (6%) by nasal cavity sabbing, and these included 3 orthopaedic surgeons. MRSA was also found in the patients' group, there were 23 (40%) from nasal cavities and 14 ones (25%) from surgical sites. Their PFGE types of MRSA were of A type, which were also identified in two orthopaedic surgeons. SUMMARY: We noticed that nasal cavitiy infection could occur by cross infection between doctors and patients. Surgical wound infection may occur by infection from the nasal cavity. This study underlines the importance of MRSA infection and management.
Cross Infection ; Electrophoresis ; Humans ; Methicillin Resistance* ; Methicillin* ; Methicillin-Resistant Staphylococcus aureus ; Nasal Cavity ; Staphylococcus* ; Surgical Wound Infection ; Wound Infection

The increase in mortality and morbidity associated with the use of muscle relaxants, is associated with a lack of clinical pharmacological knowledge of the drugs, and a lack of understanding the risk of postoperative residual curarization. This is due to the absence of standards for neuromuscular monitoring. Clinicians experienced in neuromuscular monitoring and using muscle relaxants in the clinic may have some queries regarding the monitoring: Why should neuromuscular monitoring be done? Are clinical tests really not effective? Why is it not good when I actually perform neuromuscular monitoring? Would using sugammadex not require neuromuscular monitoring? This review answers most of the questions that many clinicians have, and also forwards the knowledge required of clinicians.
Delayed Emergence from Anesthesia ; Mortality ; Muscle Relaxation ; Neuromuscular Monitoring*

PURPOSE: Postoperative wound infection accounts for approximately 15% of all hospital infections. Methicillin-resistant Staphylococcus aureus (MRSA) infections are 14% of the domestic hospital infections and this is increasing in incidence over time. The aim of this study was to retrospectively evaluate the relationship between wound dehescence after urologic surgery and MRSA infection. MATERIALS AND METHODS: Thirty patients (25 males and 5 females) who experienced wound dehescence after urologic surgery were subdivided into two separate groups; the MRSA group and non-MRSA group, and they were retrospectively analyzed via a chart review according to the age of the patients, the associated disease, the hepatic or renal functional status, the admission duration, the use of preoperative antibiotics and the number and duration of inserted catheters. RESULTS: The mean age of the MRSA group and the non-MRSA group was 62.6+/-12.4 years and 59.3+/-19.9 years, respectively (p=0.235). The elapsed operative time in the MRSA group and non-MRSA group was 355.8+/-99.5 minutes and 305.8+/-90.2 minutes, respectively (p=0.021). Contrary to 35.2+/-23.6 days of catheter duration in the MRSA group, that of the non-MRSA group was 14.6+/-8.5 days (p=0.007). The tendency for MRSA infection was observed for an increased duration of drain placement, a decreased hepatic or renal function and the preoperative antibiotic use. The extent of admission was obviously longer for the MRSA group (39.6+/-23.5 days) than for the non-MRSA group (28.9+/-9.9 days) (p=0.013). CONCLUSIONS: Wound dehescence assocated with MRSA infection is intimately related to the elapsed operative time and the period of catheter-insertion, which in turn increases the number of admission days.
Anti-Bacterial Agents ; Catheters ; Cross Infection ; Humans ; Incidence ; Male ; Methicillin Resistance ; Methicillin-Resistant Staphylococcus aureus* ; Operative Time ; Retrospective Studies ; Staphylococcus aureus ; Surgical Wound Infection ; Wound Infection ; Wounds and Injuries*

Over the years, strategies in the prevention and management of surgical site infections (SSI) of patients in the Philippines have never been standardized. Several guidelines released by international foreign bodies have been found to be either conflicting or inappropriate for adaptation in the local context.To address these issues, the Philippine College of Surgeons (PCS),in collaboration with the Philippine Hospital Infection Control Society (PHICS), Philippine Hospital Infection Control Nurses Association (PHICNA) and Operating Room Nurses Association of the Philippines, Inc. (ORNAP), initiated the development and adaptation of country-specific SSI guidelines in 2017. The new recommendations are based on the latest clinical practice guidelines released for the past five years and consensus by a panel of experts in the Philippines, through the assistance of a guideline development team engaged by PCS. Thirty-six (36) recommendations on different aspects of care were outlined. Implementation of an SSI surveillance program was also advised for health facilities.The new guidelines are intended to serve as the local benchmark for the prevention and management of SSI for surgeons and practitioners,taking into account their situation and experience in the Philippines. It is expected to improve the standard of care provided by health facilities and contribute to the reduction of the prevalence and incidence of SSI in the country

Human ; Surgical Wound Infection ; Consensus ; Operating Rooms ; Cross Infection ; Standard Of Care ; Operating Room Nursing ; Perioperative Nursing ; Hospitals ; Surgeons ; Foreign Bodies

PURPOSE: Despite advances in infection control practices, Surgical Site Infections (SSIs) remain a substantial cause of morbidity and mortality among hospitalized patients. This study was undertaken to determine prospectively the incidence of postoperative wound infections in surgical patients and to identify the risk factors associated with the development of wound infections. METHODS: Prospective data on 761 surgical operation patients in the department of surgery at Ewha Womans University Mokdong Hospital were collected over a 7 month-period from May 1, to December 31, 2001. The Centers for Disease Control and Prevention (CDC)'s definitions of surgical wound infections were used. RESULTS: A total of 761 patients were observed over 30 days. The overall incidence of wound infection was 2%. SSIs were significantly associated with the degree of wound contamination (P=0.0004). The infection rate increased as the degree of wound contamination increased from clean (1.4%) through clean-contaminated (1.8%) and contaminated (1.8%), to dirty- infected wound (12.7%). The infection rate was related with the American Society of Anesthesiologists (ASA) preoperative assessment score (P=0.00153). There were no SSIs from laparoscopic surgery. The duration of operation was not associated with an increase in wound infections. Enterococcus faecium and Staphylococcus aureus were the most frequently isolated organisms. Three out of the five (60%) cases of E. faecium were vancomycin-resistant enterococci (VRE) and all of three cases of S. aureus were methicillin- resistant Staphylococcus aureus (MRSA). CONCLUSION: This study confirms that the degree of wound contamination is a significant preoperative risk factor for SSI. Many antibiotic-resistant bacteria such as MRSA and VRE were isolated. Accordingly, infection control practitioners need to consider this risk factor in the design of effective infection control strategies. There should be another safe and feasible option available for the treatment of selective patients.
Bacteria ; Centers for Disease Control and Prevention (U.S.) ; Cross Infection ; Enterococcus faecium ; Female ; Humans ; Incidence ; Infection Control ; Infection Control Practitioners ; Laparoscopy ; Methicillin-Resistant Staphylococcus aureus ; Mortality ; Prospective Studies* ; Risk Factors ; Staphylococcus aureus ; Surgical Wound Infection* ; Wound Infection ; Wounds and Injuries