No Abstract available.
Osteoporosis* ; Parathyroid Hormone*

No abstract available.
Calcium* ; Lithium* ; Parathyroid Hormone*

No abstract available.
Parathyroid Hormone-Related Protein

No abstract available.
Aging* ; Estrogens* ; Metabolism* ; Parathyroid Hormone*

No abstract available.
Aging* ; Estrogens* ; Metabolism* ; Parathyroid Hormone*

No abstract available.
Hand* ; Parathyroid Hormone-Related Protein*

Parathyroid carcinoma is a rare endocrine malignancy accounting for 0.5% to 4.0% of all cases of hyperparathyroidism and commonly present as hypercalcemia and parathyroid hormone (PTH) elevation. Nonfunctional parathyroid carcinoma does not show symptoms of hyperparathyroidism and only showed a vague indication of being pathologic, even when detected late. The optimal treatment is en bloc resection of the cancer, but frequent local recurrence after surgery has been reported. Adjuvant local treatment such as radiotherapy may improve the likelihood local control in cases with incompletely resected or microscopic residual tumor. The results of this study point to a case of nonfunctional parathyroid carcinoma treated by external beam radiotherapy after en-bloc resection of cancer.
Accounting ; Hypercalcemia ; Hyperparathyroidism ; Neoplasm, Residual ; Parathyroid Hormone ; Parathyroid Neoplasms ; Recurrence

The frequency of hyperparathyroidism has slowly increased recently with routine measurement of serum calcium and increasing awareness by the public of the disease. The success of parathyroid surgery depends on the identification and removal of all hyperactive parathyroid tissue. Advances in preoperative imaging, such as high resolution ultrasonography and Tc-99m sestamibi, plays a major role in the targeted operative approach that does not disturb the normal parathyroid glands. Tc 99m sestamibi scanning is generally viewed as the gold standard for preoperative parathyroid localization with high sensitivity and specificity, while the intraoperative measurement of intact parathyroid hormone (iPTH )provides the surgeon with a quantitative test that predicts the postoperative serum calcium level and can justify early closure or further exploration for hyperfunctioning parathyroid gland. Therefore, the combination of Tc-99m sestamibi and rapid intraoperative iPTH measurement enable minimally invasive techniques for multiple parathyroid lesions. The combination of Tc-99m sestamibi and intraoperative iPTH monitoring, indispensable for securing operative success, represents an accurate and effective diagnostic tools. The authors experienced a case that proved the combination of Tc-99m sestamibi and rapid intraoperative PTH monitoring useful and made a report with a review of literature.
Calcium ; Hyperparathyroidism ; Parathyroid Glands ; Parathyroid Hormone ; Parathyroidectomy* ; Sensitivity and Specificity ; Ultrasonography

Intra-operative parathyroid hormone (IOPTH) assay is a useful tool to confirm complete excision of all hyper-functioning parathyroid gland tissue. In this report, we describe a case with successful localization of distant metastasis in a patient with parathyroid carcinoma using the IOPTH assay. A 53-year-old man presented to our clinic with a serum calcium level of 11.8 mg/dL and an intact PTH level of 233.3 pg/mL. He had been treated for parathyroid carcinoma eleven years ago. Two suspected metastatic lesions were detected on the chest computed tomography. Due to the vastly different surgical field necessary to excise each lesion, we preferentially removed only one lesion and we monitored the other remaining suspected lesion without resection via IOPTH assay. Six months later, the patient's serum calcium and intact PTH levels remained within their normal ranges. To the best of our knowledge, this is the first case to effectively utilize IOPTH assay for the management of metastatic parathyroid carcinoma.
Calcium ; Humans ; Middle Aged ; Neoplasm Metastasis ; Parathyroid Glands ; Parathyroid Hormone ; Parathyroid Neoplasms ; Reference Values ; Thorax

Acute pancreatitis caused by primary hyperparathyroidism-induced hypercalcemia is a rare condition, as acute pancreatitis is typically associated with a decrease in serum calcium levels. If hypercalcemia is present in a patient with acute pancreatitis, the possibility of hyperparathyroidism should be considered, and parathyroid hormone levels should be evaluated and the parathyroid gland imaged. We present a case of a 48-year-old male with acute recurrent pancreatitis caused by hyperparathyroidism. Initially, the acute pancreatitis improved after conservative therapy. However, the patient relapsed 1 month later. The patient had hypercalcemia and was diagnosed with parathyroid adenoma. He underwent surgical resection of the parathyroid adenoma and recovered. After 24 months of the treatment, there was no recurrence of the hypercalcemia or pancreatitis.
Calcium ; Humans ; Hypercalcemia ; Hyperparathyroidism ; Male ; Middle Aged ; Pancreatitis ; Parathyroid Glands ; Parathyroid Hormone ; Parathyroid Neoplasms ; Recurrence