BACKGROUND AND OBJECTIVE: Intrasinus ossification is rarely observed in the imaging study of paranasal sinus. The pathologic findings and the treatment principles of the radiodense lesions which are located in the inflammatory lesion of the paranasal sinuses are not clarified enough. In this study, we try to describe the CT findings and histopathology of intrasinus calcification in chronic paranasal sinusitis. MATERIALS AND METHODS: Ten patients who underwent sinus surgery for the abnormal bony calcification were included in this study. The shape and location of intrasinus calcification were evaluated in the CT. The pathologic specimens were reviewed. RESULTS: Most of the patients had high Hounsfield unit at CT imaging. Osteomas were found in 7 patients, fungal sinusitis in 2 patients, and the new bone formation in a patient. Osteoma and the new bone formation were located at the periphery of the sinus cavities. The calcifications in fungal sinusitis were found at the central of the sinuses. Infiltration of the inflammatory cells were found in the matrix of fungal sinusitis, but not in others. CONCLUSION: Intrasinus radiodense lesions are different in the location and shape according to the pathology. The findings in the CT imaging of intrasinus calcification are helpful for the differentiation of these lesions.
Humans ; Osteogenesis ; Osteoma ; Paranasal Sinuses ; Pathology ; Sinusitis*

A 39 years old male patient was admitted with the right of facial abnormalities and gradually protruding in right eye more than 30 years. CT shows high mixed density, clear boundary, and the right eye was crowded to the right. Giant tumor had completely been excised, and the result was fine. The outline figure and function of patients were obviously improved. The pathological examination after resection showed ossifying fibroma.
Adult ; Fibroma, Ossifying ; diagnosis ; Humans ; Male ; Nasal Cavity ; pathology ; Paranasal Sinus Neoplasms ; diagnosis ; Paranasal Sinuses ; pathology

Adult ; Humans ; Male ; Nasal Cavity ; pathology ; Orbit ; pathology ; Paranasal Sinuses ; pathology ; Skull Neoplasms ; pathology ; surgery

Adenocarcinoma/pathology* ; Gene Rearrangement ; Humans ; Nasal Cavity/pathology* ; Nose Neoplasms/surgery* ; Paranasal Sinus Neoplasms/surgery* ; Paranasal Sinuses/pathology*

Rosai-Dorfman disease in nasal cavity and nasal sinuses is known as an idiopathic proliferative disease of histiocytes with a distinct morphologic feature and is very rare. It is easy to relapse and be misdiagnosed. In on case, the infiltrating histiocytes had large round or oval nuclei. The cytoplasm was abundant, granular or vacuolated and foamy. Immunohistochemical studies showed that the histiocytes were strongly reactive with antibodies against S100 and CD68. The diagnosis of extranodal RDD in the paranasal sinuses could be differentiated with rhinoscleroma, eosinophilic granuloma, plasmacytoma, or fibrous histiocytoma. It showed that the identification of the distinctive histiocytes which are typically immunoreactive to S100 and CD68 can be quite helpful for correct diagnosis.
Adult ; Histiocytosis, Sinus ; pathology ; Humans ; Male ; Nasal Cavity ; pathology ; Paranasal Sinuses ; pathology

Pleomorphic adenoma (PA) is the most common benign tumor of the salivary glands. Originating from the nasal cavity is very rare. This paper reports one case of pleomorphic adenoma of the inferior nasal turbinate to analyze the clinic characteristic of this disease. Although these tumors are rarely seen in everyday practice, one should consider this possibility as an uncommon aetiology when confronted with an intranasal mass.
Adenoma, Pleomorphic ; pathology ; Humans ; Nasal Cavity ; Nose Neoplasms ; pathology ; Paranasal Sinuses ; Turbinates ; pathology

OBJECTIVETo investigate the mechanism of fungi invasion into the mucosal tissue, and to analyse the clinical-pathological relationship.

METHODSThe clinical data of 16 patients with invasive mycosis in the nose and paranasal sinus proved by pathologic examination between Apr, 1984 and Aug, 2002 were reviewed retrospectively. There were 7 males and 9 females with an average age of 48.6 years. The pathologic morphology of fungi found in these patients was investigated. Fourteen of 16 tissue samples from the paranasal sinuses obtained by endoscopic operation were cultivated for the fungi. One sample of invasive mycosis was observed under electron-microscope.

RESULTSFourteen cases were found to have following underlying conditions, including diabetes (n = 4), malignant tumor (n = 5). The infected sites were as follows: 7 cases presenting in unilateral maxillary sinus, 6 cases involving over two nasal sinuses, 8 cases invading the orbit. Of all 16 patients, 15 were positive (93.7%) for the culture. The positive rate of aspergillus was 62.5% and mucoraceae was 25.0%. The overall mortality rate was 50.0% after investigation from 6 months to 5 years. From 16 surgical specimens, hypha were proved in all cases for histopathologic methods. All of the 16 granulomatous and crumbley materials from the paranasal sinuses were found that inflammatory responses were predominantly neutrophilic leucocytes invasion (100%), suppurative granuloma formed in 15 cases (93.7%). Invasive diseases were characterized by prominent infarcts (27.8%), angio-invasion (100%), and surprisingly, prominent optic nervous invasion (16.7%) in biopsies.

CONCLUSIONSThe incidence of invasive mycosis is correlated with patients who suffered from diabetes, malignant tumor and other basic diseases causing depression of immunological function. The pathologic study shows that the fungi which invade the tissue are mostly aspergillus or mucoraceae, and the fungal vasculitis is the direct reason for tissue damage.

Adult ; Aged ; Aspergillosis ; pathology ; Aspergillus ; Female ; Humans ; Male ; Middle Aged ; Paranasal Sinuses ; microbiology ; pathology ; Retrospective Studies

Adult ; Female ; Histiocytosis, Sinus ; Humans ; Nasal Cavity ; pathology ; Paranasal Sinuses ; pathology

Female ; Foreign Bodies ; Humans ; Middle Aged ; Nasal Cavity ; pathology ; Paranasal Sinuses ; pathology

Synovial sarcoma is a malignant soft tissue with unknown origin. Although head and neck region is the second common site of involvement, rare cases have been reported in Para nasal sinus and larynx. We presented two cases of synovial sarcoma, one of which arised from maxillary sinus and the other from laryx, and re- view the literature to sum up the diagnosis and treatment strategies. The conclusion is that synovial sarcoma in the head and neck still raises diagnostic and therapeutic issues. Surgical excision with wide margins is essential and necessary, usually associated radiotherapy. The effect of chemotherapy remains to explored.
Head and Neck Neoplasms ; pathology ; Humans ; Larynx ; Maxillary Sinus ; Paranasal Sinuses ; Sarcoma, Synovial ; pathology