Hypokalemic periodic paralysis is a rare disorder characterized by sudden onset of weakness and low serum potassium levels. We report a case provoked by combination chemotherapy including prednisolone. A 23-yr-man, diagnosed with diffuse large B-cell lymphoma, received chemotherapy. He developed significant weakness in upper and lower extremities during chemotherapy, and his serum potassium level was 1.7 mmol/L. Potassium replacement restored the weakness. Further workup revealed that prednisolone had provoked hypokalemic paralysis. As prednisolone triggered an attack of hypokalemic periodic paralysis, it should be administered with caution, particularly in patients with periodic paralysis.
Drug Therapy ; Drug Therapy, Combination ; Humans ; Hypokalemic Periodic Paralysis ; Lower Extremity ; Lymphoma, B-Cell* ; Paralysis* ; Potassium ; Prednisolone

Hypokalemic periodic paralysis is a rare disorder characterized by sudden onset of weakness and low serum potassium levels. We report a case provoked by combination chemotherapy including prednisolone. A 23-yr-man, diagnosed with diffuse large B-cell lymphoma, received chemotherapy. He developed significant weakness in upper and lower extremities during chemotherapy, and his serum potassium level was 1.7 mmol/L. Potassium replacement restored the weakness. Further workup revealed that prednisolone had provoked hypokalemic paralysis. As prednisolone triggered an attack of hypokalemic periodic paralysis, it should be administered with caution, particularly in patients with periodic paralysis.
Drug Therapy ; Drug Therapy, Combination ; Humans ; Hypokalemic Periodic Paralysis ; Lower Extremity ; Lymphoma, B-Cell* ; Paralysis* ; Potassium ; Prednisolone

This paper introduces the specific clinical experience of professor
Acupuncture Points ; Acupuncture Therapy ; Facial Paralysis/drug therapy* ; Herbal Medicine ; Humans ; Moxibustion

Professor HE Tianyou's unique understanding and treatment characteristics for intractahle facial paralysis are introduced. In clinical practice professor HE highly values acupoint selection and manipulation application, and integrates Chinese and western medicine to flexibly choose acupoints and formulate prescriptions according to syndrome differentiation and location differentiation, besides, he creates several specialized manipulation methods including "tug-of war opposite acupuncture method" and "tractive flash cupping". Based on strengthening body and dredging collaterals. more attention is given on stimulation to local paralyzed facial nerves; meanwhile acupuncture and medication are combined to improve clinical efficacy. During the treatment, the important role of psychological counseling on patient's anxiety is emphasized, and comprehensive treatment is given physically and psychologically in order to achieve the purpose of total rehabilitation.
Acupuncture Points ; Acupuncture Therapy ; Adult ; Drugs, Chinese Herbal ; administration & dosage ; Facial Paralysis ; drug therapy ; therapy ; Female ; Humans ; Medicine

STUDY DESIGN: A review of related literatures of diagnosis and treatment of spinal tuberculosis. OBJECTIVES: The aim of the study was to discuss treatment strategies by understanding of emerging problems related to spinal tuberculosis. SUMMARY OF LITERATURE REVIEW: Owing to modern diagnostic modalities, development of prevention and chemotherapy, the incidences of tuberculosis infection including spinal tuberculosishave been decreasing. Moreover, these medical these improvements of medical and surgical treatments the improvement of surgical techniques for spinal tuberculosis reduced the incidence of kyphosis or neurologic complications such as Pott's paralysis. MATERIALS AND METHODS: Review of related literatures. RESULTS: Recently,the occurrence of multi-drug resistant strain, an increasing number of opportunistic infections and an atypical presentation in spinal tuberculosis are emerging as new challenges. CONCLUSIONS: An appropriate diagnosis and surgical interventions are our obligation as clinicians dealing with this unique infectious disease to minimize the complications for the treatment of spinal tuberculosis.
Communicable Diseases ; Diagnosis ; Drug Therapy ; Incidence ; Kyphosis ; Opportunistic Infections ; Paralysis ; Spine* ; Tuberculosis* ; Tuberculosis, Spinal

Child, Preschool ; Facial Paralysis ; etiology ; Female ; Hand, Foot and Mouth Disease ; complications ; drug therapy ; Humans

BACKGROUND AND OBJECTIVES: Since Sir Charles Bell (1829) demonstrated that motor innervation of the muscles of facial expression is by cranial nerve VII, many more research have contributed to the diagnosis and treatment of facial nerve paralysis. We attempted to evaluate the causes, arrive at accurate diagnosis and determine the treatment for facial nerve paralysis. MATERIALS AND METHODS: The authors analyzed 65 cases of facial nerve paralysis diagnosed at the Department of Otolaryngology, Hanyang University Hospital from January 1993 to December 1995. RESULTS: 1) The most common age group was the twenties. 2) The most common cause was trauma (23 cases, 35.4%). 3) The degree of facial nerve paralysis that were most common on first visits was Grade IV, based on the House-Brackmann grading method. 4) 38 cases (58.5%) were treated with chemotherapy and 27 cases (41.5%) were treated with surgical therapy. 5) Surgical techniques used were facial nerve decompression in 11 cases (40.8%), end to end anastomosis in 4 cases (14.8%), myringotomy with v-tube insertion in 4 cases (14.8%), tumor resection in 3 cases (11.1%), nerve graft in 2 cases (7.4%), mastoidectomy only in 2 cases (7.4%), and muscle transposition in one case (3.7%). CONCLUSION: In our review, the the most common degree of facial nerve paralysis on patients' first visits was Grade IV according to the House-Brackmann grading method. Statistically, there was no sexual difference in the incidences of facial nerve pals. The causes of facial nerve palsy due to trauma are recently on the rise because of increased traffic accident. However, iatrogenic incidents are decreasing because of the advance in the technical and instrumental development.
Accidents, Traffic ; Decompression ; Diagnosis ; Drug Therapy ; Facial Expression ; Facial Nerve* ; Humans ; Incidence ; Muscles ; Otolaryngology ; Paralysis* ; Transplants

OBJECTIVE: To investigate the clinical features and medication of unilateral idiopathic vocal fold paralysis. METHOD: Thirty-nine of medical treated patients with unilateral idiopathic vocal fold paralysis were retrospectively studied, and relevant literatures were reviewed. RESULT: After 4 to 19 days of medical therapy, 9 patients were cured, the vocal fold movement of 18 sufferers were improved, and 12 pantients were not healed. CONCLUSION Unilateral idiopathic vocal fold paralysis is common, and the treatment efficacy of medicine is almost the same with others. Unilateral idiopathic vocal fold paralysis is a disease with spontaneous recovery, which should be followed up.
Humans ; Retrospective Studies ; Treatment Outcome ; Vocal Cord Paralysis ; drug therapy ; Vocal Cords ; physiopathology

Primary central nervous system atypical teratoid/rhabdoid tumors are rare and extremely aggressive malignancies of early childhood. These tumors are most common in infants less than 2 years of age. Diagnosis is based on distinctive light microscopic and immunohistochemical findings, coupled with a molecular genetic analysis. A histologic features of these tumors are epithelial and/or mesenchymal components in addition to rhabdoid, with or without neuroepithelial fields. The expression of the epithelial membrane antigen, vimentin, and the smooth muscle actin are characteristic of these tumors. Treatment includes surgery, chemotherapy, and radiotherapy. Prognosis is poor despite of an aggressive therapy. We report one case of an atypical teratoid/rhabdoid tumor in a young child. She is an 18 month-old-girl who presented with central type facial palsy. After extensive surgery she improved transiently but relapsed immediately. Her condition was not permitted to receive radiotherapy or chemotherapy. Thereafter, with phrenic nerve palsy, she suffered from recurrent episodes of pneumonia and respiratory difficulties. Finaly, she was expired three months after the diagnosis and treatment.
Actins ; Central Nervous System ; Cerebellum* ; Child ; Diagnosis ; Drug Therapy ; Facial Paralysis ; Humans ; Infant ; Molecular Biology ; Mucin-1 ; Muscle, Smooth ; Paralysis ; Phrenic Nerve ; Pneumonia ; Prognosis ; Radiotherapy ; Vimentin

Leukemic involement of the temporal bone is not uncommon, but facial paralysis is rare as the presenting sign. A 16-year-old boy suddenly developed otalgia, facial nerve paralysis, tinnitus and vertigo. Four months ago, acute myelogenic leukemia was detected and chemotherapy was done with incomplete resolution. The initial examination revealed facial nerve paralysis, mixed hearing loss, spontaneous nystagmus but peripheral blood picture was normal. On the fourth hospital day, simple mastoidectomy was performed for drainage and diagnosis. The harvested tissue showed leukemic infiltration and subsequent peripheral blood picture revealed immature cells. Patient refused further evaluation and chemotherapy, and three months later he died of intracranial hemorrhage. We report a case of acute myelogenic leukemia with facial nerve paralysis.
Adolescent ; Diagnosis ; Drainage ; Drug Therapy ; Earache ; Facial Nerve* ; Facial Paralysis ; Hearing Loss, Mixed Conductive-Sensorineural ; Humans ; Intracranial Hemorrhages ; Leukemia* ; Leukemic Infiltration ; Male ; Paralysis* ; Temporal Bone ; Tinnitus ; Vertigo