The authors reported a PCR-based protocol for the detection of Human papilloma virus in vaginal swab speci
Papilloma ; Papilloma/virology ; Diagnosis

No abstract available.
Diagnosis* ; Papilloma*

BACKGROUNDS AND STUDY AIMS: Multiple biliary papillomatosis (MBP) is an uncommon disease. This study was undertaken to review cases with respect to describing clinical features and characteristical cholangiographic findings, and to define the role of cholangioscopy in the diagnosis and treatment of this disorder. PATIENATS AND METHODS: from 1990 to 1997, nine patients (mean age; 57.3 years, 6 men and 3 women) were diagnosed as having MBP arnong 5,361 cases of endoscopic retrograde cholangiography (ERC) conducted at our center. A retrospective analyses of the cholangiographic and cholangioscopic findings as well as clinieal features were performed.
Cholangiography ; Diagnosis ; Humans ; Male ; Papilloma* ; Retrospective Studies

PURPOSE: It is well recognized that distinguishing benign papillary lesions from malignant papillary lesions on core needle biopsy may pose difficult diagnostic problems. This study was conducted to define the potential role of ultrasoundguided core biopsy for the diagnosis of papillary lesions of the breast. METHODS: Twelve hundred and seventy nine women consecutively underwent 14-gauge core biopsy between January 2004 and December 2006. Of the 1,279 patients, 42 patients (3.2%) had papillary lesions of the breast on core needle biopsy. Of these 42 patients, 35 patients underwent surgical excision or sono-guided vacuum assisted excision. We compared the pathologic results of the excised specimens with the pathologic results on core needle biopsy. RESULTS: Of the 35 patients, 23 patients underwent surgical excision and 12 patients underwent sono-guided vacuum assisted excision. Three patients with intraductal papilloma without atypism on the core needle biopsy were confirmed to have intraductal papilloma accompanied with atypism by the final pathology. All 4 patients with papillomatosis or intraductal papilloma with atypism at core needle biopsy were confirmed to have intraductal papilloma with atypism by the final pathology. There were no patients identified to have breast cancer. CONCLUSION: Our results revealed the accuracy of core needle biopsy for making the diagnosis of papillary lesions of the breast. Surgical excision may not always be necessary for papillary lesion of the breast that is diagnosed on core needle biopsy. Surgical excision is considered in patients with papillomatosis or papillary lesions with atypism seen on core needle biopsy.
Biopsy ; Biopsy, Large-Core Needle* ; Breast Neoplasms ; Breast* ; Diagnosis ; Female ; Humans ; Papilloma ; Papilloma, Intraductal ; Pathology ; Vacuum

Vulvar vestibular papillomatosis (VVP) is a benign condition that can be viewed as the female equivalent of male pearly penile papules. Clinically, VVP is quite often misdiagnosed as condyloma acuminatum. As opposed to condyloma, VVP lesions arise from a distinct mucosal base, match the color of the surrounding mucosa, show symmetrical distribution, and are limited to the inner aspect of the labia minora. Although VVP is quite well known in the gynecological field, this disease entity is not commonly recognized in dermatology settings. Furthermore, a literature search for VVP revealed only nine reports in dermatological journals including one report from Korea. Therefore, through our report we wish to create awareness among dermatologists regarding the occurrence of this frequent but often ignored entity. Recognizing and understanding that papillomatosis of the vulvar vestibule is a normal variant will help dermatologists to avoid incorrect diagnosis and repeated unnecessary treatment.
Dermatology ; Diagnosis ; Female ; Humans ; Korea ; Male ; Mucous Membrane ; Papilloma*

PURPOSE: The purpose of this study is to describe the CT and MR findings of inverted papilloma and to determine the specific differential finding between inverted papilloma with and without coexisting malignancy. MATERIALS AND METHODS: Twenty-two histopathologically proven inverted papillomas were included in this study; in six patients there was coexisting malignancy. Twenty-two CT images and eight MR images were retrospectively reviewed. RESULTS: On CT images, the inverted papillomas were seen as unilateral sinonasal masses with bone remodeling (n=15) rather than bone destruction (n=1) and showed iso- or slightly high attenvation. Three of the six malignant cases showed aggressive bone destruction and widespread extension into the orbit, intracranial and buccal spaces, and pterygopalatine fossa. On MR images, the inverted papillomas (n=3) were iso- (n=2) or slightly high (n=1) in signal intensity in relation to muscle on T1 weighted images, and high (n=3) on T2 weigihted images. Gadolinium enhanced images showed heterogenous moderate enhancement. In the cases of coexisting malignancy (n=5), the masses were iso- (n=5) on T1 weighted images, high (n=5) on T2 weighted images and also showed heterogenous moderate enhancement. CONCLUSION: Inverted papilloma should be considered in the differential diagnosis of a bulky unilateral nasal mass extending into the adjacent paranasal sinuses, especially in an elderly patient with chronic nasal obstruction. Although there were no specific differential findings in signal intensiy and enhancement pattern on CT and MR images between benign and malignant inverted papilloma, aggressive bone destruction and widespread extension beyond the sinonasal cavity are findings which are highly suggestive of coexisting malignancy.
Aged ; Bone Remodeling ; Diagnosis, Differential ; Gadolinium ; Humans ; Nasal Obstruction ; Orbit ; Papilloma ; Papilloma, Inverted* ; Paranasal Sinuses ; Pterygopalatine Fossa ; Retrospective Studies

Adult ; Female ; Humans ; Nasal Mucosa ; pathology ; Nose Neoplasms ; diagnosis ; surgery ; Papilloma ; diagnosis ; surgery

Papilloma invading the cornea is a benign tumor which needs differential diagnosis from malignant tumor and ocular surface squamous neoplasia. A sixty three year-old Korean female visited our hospital, complaining decreased visual acuity and a recurrent symptom of conjunctival irritation for one year. On her ocular examination the visual acuity of the right eye was 1.0 and that of the left, 0.7(noncorrectable). It was also found that the ocular surface mass, lying over the temporal and superior side of bulbar conjunctiva and invading 1/3 area of the corneal surface, clinically resembled that of ocular surface squamous neoplasia. A preoperative cytologic examination showed some clusters of epithelial cells without any dysplastic cell. The final diagnosis of a sessile papilloma invading the cornea was confirmed by a pathological examination after surgical excision. We present the above case with a brief review of literature for the first time in Korea.
Conjunctiva ; Cornea* ; Deception ; Diagnosis ; Diagnosis, Differential ; Epithelial Cells ; Female ; Humans ; Korea ; Papilloma* ; Visual Acuity

No abstract available.
Bile Duct Neoplasms/*diagnosis ; *Bile Ducts, Intrahepatic ; Female ; Human ; Middle Aged ; Papilloma/*diagnosis

BACKGROUND: Papillary lesions of the breast exhibit bloody nipple discharge, often with no evidence of a palpable tumor. These lesions occasionally present some difficult diagnostic and therapeutic problems as they may be histologically benign, borderline or malignant. The types of surgery should be selected according to the different lesion characteristics. A favorable result of appropriate surgery is no recurrence. METHODS: The authors performed a retrospective study of 60 patients treated for the papillary lesions of the breast over the period from January 1990 to July 1998 at Inje University Pusan Paik Hospital. The study examined clinical characteristics by comparative analysis of clinical features, diagnostic methods (mammogram, ultrasound, galactogram & fine needle aspiration cytology) and surgical procedures among the various types of papillary lesions of the breast diagnosed histologically. RESULTS: The patients with a papillary carcinoma or papillomatosis were all older than the mean age of 45 for the 60 patients. Nipple discharges were most frequent in multiple central papilloma patients & intraductal papilloma patients. The incidence of nipple discharge alone was 26.1% in intraductal papilloma patients. Palpable masses were most frequent in the patients with a papillary carcinoma, intraductal papilloma, or papillomatosis. Ultrasound and galactograms had the highest sensitivity (90.9%, 87.5%) in all the patients with papillary lesions. Galactograms had the highest sensitivity (89%) in the patients with nipple discharge alone. The diagnostic methods with the highest sensitivity according to the type of papillary lesion were the galactogram (84.6%) for intraductal papillomas; ultrasound (100%) for multiple central papillomas; galactogram (100%), ultrasound (100%), and FNAC (100%) in papillomatosis; and the mammogram (100%) and ultrasound (100%) for papillary carcinomas. Breast cancers (DCIS, ipsilateral/contralateral invasive ductal carcinoma, papillary carcinoma) or ADH were associated with 14 cases (23.3%) of papillary lesions of the breast, in particular, 8 cases (42.1%) of papillomatosis. The most common surgical procedures were excisional biopsies & microdochectomies for intraductal papillomas, microdochectomies for multiple central papillomas, excisional biopsies & major duct excisions for papillomatosis, and mastectomies for papillary carcinomas. The incidence of postsurgical residual lesions and the recurrence were 10% & 1.7% in all the patients with papillary lesions of the breast, and were especially high in patients with papillomatosis. CONCLUSIONS: 1) Ultrasonography & galactography seem to be the most useful diagnostic methods for papillary lesions of the breast. 2) Major duct excision is recommended as an effective treatment for papillomatosis.
Biopsy ; Biopsy, Fine-Needle ; Breast* ; Busan ; Carcinoma, Ductal ; Carcinoma, Papillary ; Diagnosis* ; Humans ; Incidence ; Mastectomy ; Nipples ; Papilloma ; Papilloma, Intraductal ; Recurrence ; Retrospective Studies ; Ultrasonography