No abstract available.
Papaverine*

No abstract available.
Papaverine*

Two techniques are available for endovascular treatment of post-SAH vasospasm: mechanical angioplasty and phamacologic infusion(papaverine or other vasodilator). The advantages of papaverine infusion are simplicity, safety, and the ability to reach small distal vessels. The disadvantages are that the treatment results may be temporary and inconsistant. The advantages of balloon angioplasty are rapid, dramatic result and consistantly successful. It is important to treat vasospasm as soon as possible for two reasons: vascular response is better and permanant ischemic damage is minimized. If ischemic symptom have developed, it may already to be late. So, the treatment of vasospasm should be proreactive rather than reactive.
Angioplasty ; Angioplasty, Balloon ; Papaverine

No abstract available.
Erectile Dysfunction* ; Male ; Papaverine

No abstract available.
Cytomegalovirus* ; Humans* ; Methotrexate* ; Papaverine*

No abstract available.
Animals ; Guinea Pigs* ; Guinea* ; Papaverine* ; Skin* ; Triamcinolone*

Snap Gauge bands were applied to measure nocturnal penile rigidity in the impotent patients and the results were compared with PBI and findings of the papaverine induced artificial erection. The results were as follows: 1. The results of Snap Gauge test were relatively competitive with the degree of erectile dysfunction which organic impotent patients complained of. 2. PBI less than 0.85 implied insufficient rigidity and PBI over 0.95 showed sufficient rigidity in Snap Gauge tests. 3. The possibility of "false positive" or "false normal" in diagnosis of the impotence was higher in the papaverine induced artificial erection tests than in the Snap Gauge tests. Conclusively, Snap Gauge band is simple to use and effective to measure quantitatively the penile rigidity reached during nocturnal erections in impotent patients.
Diagnosis* ; Erectile Dysfunction* ; Humans ; Male ; Papaverine

A variety of technique of dynamic pharmacocavernosometry have been described to evaluate cavernous veno-occlusive function: however, there is no uniquely reliable and standard method so far After intracavernous (IC) injection of 45 mg papaverine and 2.5 mg phenblamine, we performed gravity cavernosometry(GC) and pump cavernosometry(PC), ie, measurement of saline infusion rate needed to obtain and to maintain an erection and measurement of pressure decay for 30 seconds and pressure drop time to 75 mmHg when pump was turned off at 150 mmHg IC pressure. Final diagnosis of venous leakage was made by cavernosoeraphy done at 90 mmHg IC pressure. The parametric values measured by each method to diagnose venous leakage and correlation among these methods were analyzed. The etiology of impotence in 45 patients studied was psychogenic in 8, venogenic in 21, combined arteriogenic and venogenic in 16. The measurement of induction flow rate was less reliable(p<0.05) for the diagnosis of venous leak than the other methods of PC and GC (p<0.01). The standard deviations of the induction and maintenance flow rate and pressure drop time were similar to or even higher than mean values. There was correlation among all these methods. Therefore, GC and PC, particularly measurement of the intracorporeal pressure decay are believed to be valuable methods for diagnosis of the corporal-venous leakage.
Diagnosis ; Erectile Dysfunction ; Gravitation ; Humans ; Male ; Papaverine

Penile-brachial Index(P. B. I) was measured before and after injection of papaverine in 79 psychogenic impotences, 31 arteriogenic impotences and 11 neurogenic impotences. Its diagnostic usefulness was compared with qualities of papaverine induced artificial erection and pudendal angiographic findings. The results were as follows , 1. Among 31 patients with arteriogenic impotence, 17(54.8%) patients were above 0.8 in P. B. I before injection of papaverine. Thus, the arteriogenic impotence could not be excluded in patients of P. B. I. above 0.8. 2. Among the psychogenic impotences, there was no case of P. B. I. below 0.8 after injection of papaverine. So arteriogenic impotence could be like in the case of P. B. I. below 0.8. However, the arteriogenic impotence could not be excluded in the case of P. B. I. above 0.8 because 25(86.6%) patients of arteriogenic impotence were above 0.8. 3. The specificity. sensitivity and efficiency of the P. B. I. concerning prediction of response to papaverine injection were 88.2, 41.2, 80.4% in P. B. I. of 0.8. 4. The specificity, sensitivity and efficiency of the P. B. I. concerning prediction of findings of pudendal angiogram were 71.4, 90.3, 86.8% in P. B. I. of 0.9. In conclusion, it was difficult to establish the base line of normal value of P. B. I. and there was limitation of diagnostic value of the P.B.I.
Female ; Humans ; Impotence, Vasculogenic ; Male ; Papaverine ; Reference Values ; Sensitivity and Specificity

PURPOSE: To assess the erectile response to intracavernous injection of prostaglandin E1 (PGE 1) or papaverine in the impotence patients with diabetes mellitus (DM), and to determine the factors which would predict good response to either drug. MATERIALS AND METHODS: We injected papaverine (10~60 mg) or PGE1 (10~20 mg) into cavernosal tissues of 305 impotence patients with DM (mean age; 56.1 years). Erectile response was classified into poor, moderate, or good, and was comparatively analyzed according to kinds of vasoactive agents, patients` age, duration of DM and impotence, and treatment modality of DM. RESULTS: The frequency of good response to PGE1 was significantly higher than to papaverine (61.5% vs. 42.8%; p<0.05). However, no association between erectile response and patients` age, duration of impotence and DM, and treatment modality of DM was noted. CONCLUSIONS: Prostaglandin E1 seems to be more effective substance than papaverine for intracavernous injection therapy in impotence patients with DM.
Alprostadil* ; Diabetes Mellitus* ; Erectile Dysfunction* ; Humans ; Male ; Papaverine*