1.Investigation on psychological status of patients with acute pancreatitis and analysis of influencing factors
Cui CHEN ; Hong TAO ; Panrui YANG ; Haining ZHU ; Yun ZHANG ; Yiqi DU ; Zhaoshen LI ; Cun WEI
Chinese Journal of Pancreatology 2019;19(4):275-278
Objective To investigate the pshcyological status and influencing factors of patients with acute pancreatitis. Methods Acute pancreatitis patients admitted in Changhai Affiliated Hospital of Navy Medical University from December 2018 to February 2019 were enrolled, and 120 patients were selected using random number table method. Self-made general questionnaire, self-rating depressing scale, self-rating anxiety scale and coping style questionnaire were used for investigation and patients′ psychological status was evaluated. Results In this survey, 109 questionnaires were collected and eligible for final analysis. The incidence of depression in patients with acute pancreatitis was 44. 0%, and the incidence of anxiety was 20. 2%. Male patients had significantly lower anxiety and depression than women. The levels of anxiety and depression in the 31-50 age group were significantly lower than those in other age groups. The level of anxiety in patients with pancreatitis with children was significantly lower than in patients without children. The coping style of "solving problem" was significantly negatively correlated with depression and anxiety level. The"self-blame" coping style was significantly positively correlated with depression and anxiety level. The"rationalized"coping style was positively correlated with the level of depression. Conclusions The mental health status of patients with acute pancreatitis was not optimistic. Different coping styles were important factors affecting the level of anxiety and depression.
2.The optimal cutoff value of waist-to-height ratio in Chinese: based on cardiovascular risk and metabolic disease
Aihua JIA ; 陕西省榆林市第一医院内分泌科,719000 ; Shaoyong XU ; Jie MING ; Jie ZHOU ; Wencheng ZHANG ; Panrui HAO ; Qiuhe JI
Chinese Journal of Internal Medicine 2017;56(11):822-826
Objective Waist-to-height ratio (WHtR), a measurement of the distribution of body fat, correlated with abdominal obesity indicating that it might be a better predictor of cardiovascular risk and metabolic disease.We, therefore, evaluated optimal WHtR cutoff points according to the risk of framingham risk score ( FRS ) and metabolic syndrome ( MS ) in Chinese .Methods The subjects were from China National Diabetes and Metabolic Disorders Survey during 2007 -2008.Receiver operating characteristic analysis was used to examine the optimal cutoff values of WHtR according to the risk of FRS and MS . Results A total of 27820 women and 18419 men were included in the evaluation .The average age was (45.0 ±13.7 ) years.The proportions of FRS ≥10% and MS increased with WHtR both in men and women.The cutoff points of WHtR for the risk of FRS ≥10%and MS were 0.51, 0.52 in men, and 0.52, 0.53 in women, respectively.When FRS ≥10% and MS were taken into consideration with a certain weights, the pooled cutoffs of WHtR were 0.51 in men, and 0.53 in women, respectively.By using the similar method, the optimized cutoff points were 0.52, 0.51, 0.50 for men and 0.51, 0.53, 0.54 for women in age group 20-39, 40-59 and ≥60 years, respectively.Conclusions The optimal cutoffs of WHtR are 0.51 in men, and 0.53 in women for FRS≥10% in combination with MS indicating that this WHtR cutoff points might be used as indexes to evaluate obesity and risk of obesity -related diseases .
3.METTL9 mediated N1-histidine methylation of zinc transporters is required for tumor growth.
Mengyue LV ; Dan CAO ; Liwen ZHANG ; Chi HU ; Shukai LI ; Panrui ZHANG ; Lianbang ZHU ; Xiao YI ; Chaoliang LI ; Alin YANG ; Zhentao YANG ; Yi ZHU ; Kaiguang ZHANG ; Wen PAN
Protein & Cell 2021;12(12):965-970