1.Correlation analysis on college students’ attachment and locus of control
Panpan GU ; Xiaoqin ZHOU ; Chunyan ZHU
Acta Universitatis Medicinalis Anhui 2014;(7):923-925
Objective To explore the status of college students’ attachment and locus of control, and explore their relationship. Methods A total of 198 college students were surveyed adopting Experiences in Close Relationships Inventory and Internality, Powerful Others and Chance Questionnaire. Results The distribution of college student′s attachment type was not balanced,the proportion of dismissing type,security type, fearful type, preoccupied type accounting for 43. 9%,31. 3%,21. 7%,3. 1% respectively. The scores of internality, chance and powerful others were (27. 59 ± 5. 44),(17. 92 ± 6. 66),(17. 70 ± 7. 32) respectively. Attachment avoidance correlated negatively with internality(r= -0. 259,P<0. 01), and positively with chance and powerful others(r=0. 206,0. 221,P<0. 01);besides there was a positive correlation between attachment anxiety and chance,powerful others(r=0. 378, 0. 410,P<0. 01). Attachment avoidance had prediction on internality(R2 =0. 067,P<0. 01). Attachment anxiety had prediction on chance and powerful others(R2 =0. 143,0. 168,P<0. 01). Conclusion College students’ at-tachment has significant effects on locus of control.
2.Analysis of the medical service capacity of primary healthcare in Zhejiang province
Qisheng GAO ; Qing SHEN ; Dingwan CHEN ; Panpan LIU ; Huimei HU ; Ling HU ; Yanping WU ; Yaming GU
Chinese Journal of Hospital Administration 2017;33(2):106-109
Objective To analyze the medical service capacity of primary healthcare in Zhejiang province since the ongoing healthcare reform and put forward suggestions. Methods Key indicators of healthcare resources and medical service utilization from 2009 to 2015 reflecting the primary healthcare were identified,for a quantitative analysis in terms of the structure-process-outcome dimensions. Results In terms of structural service capacity,the average headcount growth rate of primary healthcare′s technical personnel was 5. 7% per year; the personnel competence structure kept improving; the hospital beds at primary institutions and their ratio among all were slightly decreased,with better devices and informatization. In terms of procedural service capacity,the proportion of primary institutions with contract-based services amounted to 89. 9%,with the standard contract signing rate up to 18. 8%. In terms of consequential service capacity,the average growth rate of the number of outpatient visits at primary institutions was 6. 3%. The amount and proportion of inpatients were slightly decreased,while the hospital bed utilization ratio was increased slightly. Conclusions It is necessary to further strengthen the training and introduction of primary healthcare professionals. The functional orientation of hospitals at various levels should be clarified, encouraging contract-signing of general practitioners, promote the medical insurance payment reform featuring the capitation payment at primary level,and improve the income distribution and incentive mechanism.
3.Prevalence, risk factors and outcomes of diastasis recti abdominis in multiparas after the second delivery
Yechun GU ; Hongbo XU ; Lina WU ; Panpan DONG ; Yiqing GU ; Panpan NIU ; Jianfeng LUO ; Zhiyun YE ; Yanlan GU
Chinese Journal of General Practitioners 2020;19(12):1157-1163
Objective:To investigate the prevalence, risk factors and outcomes of diastasis recti abdominis (DRA) in multiparas after the second delivery.Methods:From June 2017 to September 2019, 300 multiparas with an average age of (31.7±4.0) years (26 to 43 years) after the second delivery were recruited at 6 weeks postpartum from two hospitals in Wenzhou. There were 171 multiparas with two natural births,36 multiparas with one natural birth and one caesarean delivery, and 93 multiparas with two caesarean deliveries. The interrectus distance (IRD) was measured with palpation at 6 weeks, 6 months and 12 months after delivery. Data on age, height, weight before pregnancy and delivery, baby′s birth weight, abdominal circumference before pregnancy and delivery, fetus number, delivery mode and occupation type were collected. Strength and endurance of abdominal muscle was assessed using manual muscle testing and curl-ups, low back pain was assessed using Oswestry disability index(ODI), urinary incontinence was assessed with International Consultation on Incontinence guestionnaire-incontinentia urinae (ICIQ-UI) short form (ICIQ-SF), and quality of life was assessed using 36-item short form health survey (SF-36).Results:Prevalence of DRA was 51.7%(155/300), 39.3%(116/295) and 27.7%(80/289) 6 weeks, 6 months and 12 months after delivery, respectively. Logistic regression analysis indicated that age ( OR=1.39, 95 %CI:1.02-1.91, P=0.38), abdominal circumference ratio ( OR=2.31, 95 %CI:1.23-4.33, P=0.01), twins ( OR=11.41, 95 %CI:2.15-60.76, P<0.01), and cesarean section ( OR=1.44, 95 %CI:1.06-1.95, P=0.02) were the risk factors of DRA at 12 months after delivery. At 12 months after delivery, the multiparas with DRA had weaker strength and endurance of abdominal muscle ( Z=-3.62, P<0.01; Z=-8.91, P<0.01), more serious low back pain ( Z=-2.10, P=0.04), and lower quality of life on physical health ( t=-3.34, P<0.01) than the multiparas without DRA. No difference in prevalence and severity of urinary incontinence and quality of life on psychological health was found when comparing multiparas with and without DRA (χ 2=0.66, P=0.42; Z=-1.18, P=0.24; t=0.91, P=0.36). Conclusion:Multipara after the second delivery has great likelihood for DRA.Age, abdominal circumference ratio, twins, and cesarean section are the risk factors of DRA. DRA is related to abdominal muscle dysfunction, low back pain, and quality of life.
4.Effects of SP600125 at various concentrations on proliferation and osteogenesis of human adipose-derived stem cells in vitro
Lin WANG ; Huijie GU ; Xiao CHEN ; Yun ZHANG ; Liehu CAO ; Weizong WENG ; Panpan PAN ; Fang JI ; Lei CUI ; Jiacan SU
Chinese Journal of Orthopaedic Trauma 2017;19(2):157-163
Objective To elucidate the effects of SP600125 at different concentrations on the proliferation and osteo-differentiation of human adipose-derived stem cells (hASCs).Methods The hASCs harvested were cocuhured with SP600125 at concentrations of 0 μmol/L,1 μmol/L,5 μmol/L and 10 μmol/L in growth medium (OM group) and in osteogenesis medium (OM group),respectively.The DNA quantitative assay was carried out to evaluate proliferation of the hASCs;flow cytometry was used to determine the effect of SP600125 on the cell cycles of hASCs;Alkaline phosphatase level (ALP) and calcium deposition tests were conducted to observe the effects of SP600125 at different concentrations on osteogenic differentiation of the hASCs.Results The proliferation of hASCs was inhibited by 42.1% when the cells were cocultured with SP600125 at the concentration of 10 μmol/L;the suppression decreased with decreased concentration of SP600125.The hASCs of phase G0/G1 in GM cocultured with SP600125 at the concentration of 10 μmol/L were more than those in GM cocultured with dimethylsulfoxide at the same concentration.ALP test revealed that after 10 days of culture in vitro the staining was more and more weakened and scattered and the ALP activity was more and more decreased with the increased concentration of SP600125.The extracellular calcium deposition of hASCs after 14 days of culture in vitro showed that the size and number of calcium nodules decreased with the increased concentration of SP600125.Conclusion SP600125 can suppress the proliferation and osteogenic differentiation of hASCs in vitro.
5.CHADS₂versus CHA₂DS₂-VASc scoring systems for predicting left atrial thrombus in patients with nonvalvular atrial fibrillation.
Jun GU ; Fengpeng JIA ; Panpan FENG
Journal of Southern Medical University 2014;34(11):1601-1605
OBJECTIVETo assess the correlation of CHADS₂and CHA₂DS₂-VASc scores for left atrial thrombus in patients with nonvalvular atrial fibrillation and the differences in the results between the two scoring systems.
METHODSA total of 397 patients with nonvalvular atrial fibrillation were enrolled in this study. The CHADS₂and CHA2DS2-VASc scoring systems were used for evaluating the risk of left atrial thrombus and their differences in the scores and risk stratifications were compared. The correlation of CHADS₂ and CHA₂DS₂-VASc scores with left atrial thrombus was analyzed.
RESULTSThe average score of CHA₂DS₂-VASc was significantly higher than that of CHADS₂in these patients (1.37 ± 1.19 vs 0.63 ± 0.78, P<0.001). The proportion of high-risk group was significantly higher (P<0.001) while that of low-risk group significantly lower as stratified by CHA₂DS₂-VASc scores than by CHADS₂scores (P<0.001). Transesophageal echocardiography detected left atrial thrombus in 44 of the total patients. The prevalence of left atrial thrombus increased significantly with a higher risk stratification by CHADS₂or CHA₂DS₂-VASc scores (P<0.05). Univariate analysis showed that female gender, age ≥ 65 years, left atrium diameter ≥ 38 mm, left ventricular ejection fraction ≤ 40%, hypertension, diabetes, coronary heart disease, stroke history, CHADS₂≥ 2, and CHA₂DS₂-VASc ≥ 2 were all correlated with left atrial thrombus, but multivariate logistic analysis identified only CHA₂DS₂-VASc ≥ 2 as the independent risk factor for left atrial thrombus (OR=9.85, 95% CI: 2.178-44.542, P < 0.01).
CONCLUSIONThe average score of CHA₂DS₂-VASc is higher than that of CHADS₂and has better predictive ability for left atrial thrombus.
Atrial Fibrillation ; complications ; Echocardiography, Transesophageal ; Female ; Heart Atria ; pathology ; Humans ; Male ; Risk Factors ; Thrombosis ; complications ; diagnosis
6.Exploring on the standardized training model for residents in the department of cardiology
Jing CHANG ; Han LEI ; Kanghua MA ; Suxin LUO ; Shu QIN ; Zhong ZUO ; Hang FU ; Wei HUANG ; Ying HUANG ; Jun GU ; Panpan FENG
Chinese Journal of Medical Education Research 2012;11(6):653-656
The standardized training is an indispensible stage for the improvement of residents' comprehensive quality and for the training of high-qualified talents.The article preliminarily explored the standardized training model for residents,which was in accordance with the characteristics of the department of cardiology mainly from four aspects:the set-up of reasonable training program,the training of practical skills,the training of humanistic quality and the training of life-long learning ability.
7.CHADS2 versus CHA2DS2-VASc scoring systems for predicting left atrial thrombus in patients with nonvalvular atrial fibrillation
Jun GU ; Fengpeng JIA ; Panpan FENG
Journal of Southern Medical University 2014;(11):1601-1605
Objective To assess the correlation of CHADS2 and CHA2DS2-VASc scores for left atrial thrombus in patients with nonvalvular atrial fibrillation and the differences in the results between the two scoring systems. Methods A total of 397 patients with nonvalvular atrial fibrillation were enrolled in this study. The CHADS2 and CHA2DS2-VASc scoring systems were used for evaluating the risk of left atrial thrombus and their differences in the scores and risk stratifications were compared. The correlation of CHADS2 and CHA2DS2-VASc scores with left atrial thrombus was analyzed. Results The average score of CHA2DS2-VASc was significantly higher than that of CHADS2 in these patients (1.37±1.19 vs 0.63±0.78, P<0.001). The proportion of high-risk group was significantly higher (P<0.001) while that of low-risk group significantly lower as stratified by CHA2DS2-VASc scores than by CHADS2 scores (P<0.001). Transesophageal echocardiography detected left atrial thrombus in 44 of the total patients. The prevalence of left atrial thrombus increased significantly with a higher risk stratification by CHADS2 or CHA2DS2-VASc scores (P<0.05). Univariate analysis showed that female gender, age≥65 years, left atrium diameter≥38 mm, left ventricular ejection fraction ≤40%, hypertension, diabetes, coronary heart disease, stroke history, CHADS2≥2, and CHA2DS2-VASc≥2 were all correlated with left atrial thrombus, but multivariate logistic analysis identified only CHA2DS2-VASc≥2 as the independent risk factor for left atrial thrombus (OR=9.85, 95%CI:2.178-44.542, P<0.01). Conclusion The average score of CHA2DS2-VASc is higher than that of CHADS2 and has better predictive ability for left atrial thrombus.
8.CHADS2 versus CHA2DS2-VASc scoring systems for predicting left atrial thrombus in patients with nonvalvular atrial fibrillation
Jun GU ; Fengpeng JIA ; Panpan FENG
Journal of Southern Medical University 2014;(11):1601-1605
Objective To assess the correlation of CHADS2 and CHA2DS2-VASc scores for left atrial thrombus in patients with nonvalvular atrial fibrillation and the differences in the results between the two scoring systems. Methods A total of 397 patients with nonvalvular atrial fibrillation were enrolled in this study. The CHADS2 and CHA2DS2-VASc scoring systems were used for evaluating the risk of left atrial thrombus and their differences in the scores and risk stratifications were compared. The correlation of CHADS2 and CHA2DS2-VASc scores with left atrial thrombus was analyzed. Results The average score of CHA2DS2-VASc was significantly higher than that of CHADS2 in these patients (1.37±1.19 vs 0.63±0.78, P<0.001). The proportion of high-risk group was significantly higher (P<0.001) while that of low-risk group significantly lower as stratified by CHA2DS2-VASc scores than by CHADS2 scores (P<0.001). Transesophageal echocardiography detected left atrial thrombus in 44 of the total patients. The prevalence of left atrial thrombus increased significantly with a higher risk stratification by CHADS2 or CHA2DS2-VASc scores (P<0.05). Univariate analysis showed that female gender, age≥65 years, left atrium diameter≥38 mm, left ventricular ejection fraction ≤40%, hypertension, diabetes, coronary heart disease, stroke history, CHADS2≥2, and CHA2DS2-VASc≥2 were all correlated with left atrial thrombus, but multivariate logistic analysis identified only CHA2DS2-VASc≥2 as the independent risk factor for left atrial thrombus (OR=9.85, 95%CI:2.178-44.542, P<0.01). Conclusion The average score of CHA2DS2-VASc is higher than that of CHADS2 and has better predictive ability for left atrial thrombus.
9.Effects of yoga exercise on exercise capacity, anxiety and depression in patients with acute myocardial infarction
Pingping GU ; Xiaoping LOU ; Qian WANG ; Panpan WANG
Chinese Journal of Modern Nursing 2020;26(3):361-365
Objective To investigate the effects of yoga exercise on exercise capacity, anxiety and depression in patients with acute myocardial infarction. Methods 75 patients with emergency PCI in Cardiology Department of a Class Ⅲ Grade A hospital in Zhengzhou from January to December in 2017 were seclected as subjects and randomly divided into control group (n=37) and intervention group (n=38) by convenient sampling. The control group received routine care, including health education, psychological care, risk factor control, medication and routine exercise education;the intervention group implemented a yoga-based exercise based on the control group. The incidence of adverse cardiac events after intervention was compared between the two groups. Before and after the intervention, the 6-min walk test (6MWT), the Self-rating Anxiety Scale (SAS), and the Self-rating Depression Scale (SDS) were used to evaluate the two groups of patients. Results Within 6 months of interventional therapy, 11 patients in the control group developed angina pectoris, and 3 patients in the intervention group developed angina pectoris. The difference between the two groups was statistically significant (P<0.05). The differences of 6MWT distances between the two groups at 1st, 3rd, and 6th months after discharge were statistically significant (P< 0.05). The differences of SAS scores between the two groups at 1st, 3rd, and 6th months after discharge were statistically significant (P < 0.05). There were significant differences in SDS scores between the two groups at discharge, and 1, 3, and 6 months after discharge (P < 0.05). Conclusions Yoga-based exercise program can improve the exercise capacity of patients with acute myocardial infarction and relieve anxiety and depression.
10.Aerobic exercise combined with hyperbaric oxygen therapy can improve post-stroke cognition and reduce oxidative stress
Ting LIU ; Chuan LI ; Ling GU ; Panpan ZHANG ; Jie SHENG ; Kai ZHAO
Chinese Journal of Physical Medicine and Rehabilitation 2021;43(7):623-627
Objective:To investigate the effect of combining aerobic exercise with hyperbaric oxygen therapy on the cognition and oxidative stress of patients with post-stroke cognitive impairment (PSCI).Methods:Forty-five PSCI patients were divided randomly into a hyperbaric oxygen therapy (HBO) group (of 21) and a combination group (of 24). Both groups received HBO therapy, but the combination group also performed 30min of aerobic exercise using a cycle ergometer 5 times a week for 8 weeks. The HBO therapy involved 20min for pressurization, 20min of decompression, 60min of pressurized oxygen inhalation and 10min of air inhalation. The treatment pressure was 0.2MPa (2.0ATA). Before and after the intervention, cognitive functioning was measured using the mini-mental state examination (MMSE) and the Montreal cognitive assement (MoCA). The Barthel index quantified ability in the activities of daily living. Serum glutathione (GSH) and malondialdehyde (MDA) were measured spectrophotometrically.Results:The average MMSE scores of both groups had improved significantly after the treatment, with significantly better improvement in the combination group. After the treatment, the average MoCA score of the combination group had improved significantly while that of the HBO group had not. The average Barthel index scores of both groups improved significantly and there was no significant difference between them after the treatment. The average serum GSH increased after the treatment in the combination group, and the increase was weakly positively correlated with the increase in MMSE scores. The average MDA content of the HBO group decreased after the treatment, and the decrease was positively correlated to the increase in the MMSE scores, but again weakly.Conclusions:Aerobic exercise combined with hyperbaric oxygen therapy can effectively improve cognition among PSCI patients. Increases in serum GSH and decreases in serum MDA are weakly positively correlated with cognitive functioning.