1.A case of Weber-Christian disease.
Doo Kweon KIM ; Sang Jo PARK ; Tae Gyu WHANG ; Soon Yong LEE
Journal of the Korean Pediatric Society 1991;34(8):1157-1162
No abstract available.
Panniculitis
;
Panniculitis, Nodular Nonsuppurative*
2.Weber-Christian Disease Treated with Steroid Pulse Therapy.
Young Hun CHO ; Jun Su PARK ; Hyoung Sup KIM ; Kwang Gil LEE ; Kee Yang CHUNG
Korean Journal of Dermatology 2002;40(12):1557-1560
Weber-Christian disease is an inflammatory disease of subcutaneous fat tissue which is characterized by relapsing, febrile tender nodules and histologically lobular panniculitis. Many cases originally considered as examples of Weber-Christian disease were later found to be other diseases when lobular panniculitis was reclassified, and some authors believe that Weber-Christian disease should no longer be considered as a distinctive entity. However, there are still occasional cases which cannot be diagnosed as other specific diseases but have the characteristic manifestations of Weber-Christian disease, and they attest to the fact that Weber-Christian disease could be a distinctive disease entity. We report here a case of Weber-Christian disease in a 22-year-old female who was treated successfully with steroid pulse therapy.
Female
;
Humans
;
Panniculitis
;
Panniculitis, Nodular Nonsuppurative*
;
Subcutaneous Fat
;
Young Adult
3.Ultrasonographic Findings of Weber-Christian Disease of the Breast: A Case Report.
Ji Youn JANG ; Yun Woo CHANG ; Dong Wha LEE
Journal of the Korean Radiological Society 2005;52(4):285-287
Weber-Christian disease is a rare inflammatory disease of subcutaneous fat necrosis that may or may not involve systemic disease. We report the results of a breast sonograph of a case diagnosed as a form of an acute lobular panniculitis affecting the breasts and upper limbs.
Breast*
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Necrosis
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Panniculitis
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Panniculitis, Nodular Nonsuppurative*
;
Subcutaneous Fat
;
Ultrasonography
;
Upper Extremity
4.Two Cases of Weber-Christian Disease.
Jong Sun SHIN ; Ryu Sung KIM ; Tae Ha WOO
Korean Journal of Dermatology 1969;7(1):33-36
Weber-Christian disease is a relapsing, febrile, nodular, nonsuppurative inflammation of the subcutaneous fat tissue. Many authors reported these cases which illustrate the great variability of the clinical manifestation, such as acute or chronic, fulminating or transient, febrile or non febrile, systemic or cutaneous. Two of our cases have had recurrent painful subeutaneous nodules without fever for several years. Biopsy showed a nonspecific inflammatory panniculitis with lymphocytes chiefly, and small amount of histiocytes and foamy cells. It should be suggested Weber-Christian disease when subcutaneous nodules appear recurrently same areas of the whole body surface except anterior aspects of tibia even if no fever as systemic manifestation. Treatment with steroid and chloroquine diphosphete produced good improvement.
Biopsy
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Chloroquine
;
Fever
;
Histiocytes
;
Inflammation
;
Lymphocytes
;
Panniculitis
;
Panniculitis, Nodular Nonsuppurative*
;
Subcutaneous Fat
;
Tibia
5.Remediable Hyperglycemia in a Patient with Weber-Christian Disease.
Woong Ryong JUNG ; Jung Ah SHIN ; Jun Ki MIN
The Journal of the Korean Rheumatism Association 2007;14(3):279-284
Weber-Christian disease (WCD) is an inflammatory disease of subcutaneous fat tissue which is characterized by relapsing, febrile tender nodules and histologically lobular panniculitis. Any area of the body containing fat can be affected by WCD. Several cases of WCD have been reported as involvement of the heart, lung, liver and kidney. Acute illness (ex. acute myocardiac infarction, infection, etc) can be complicated with stress-related hyperglycemia and increase insulin restistance. Finally this case show that Weber-Christian disease accompanied by marked hyperglycemia and insulin resistance, which resolved soon after corticosteroid.
Heart
;
Humans
;
Hyperglycemia*
;
Infarction
;
Insulin
;
Insulin Resistance
;
Kidney
;
Liver
;
Lung
;
Panniculitis
;
Panniculitis, Nodular Nonsuppurative*
;
Subcutaneous Fat
6.Weber-Christian disease presenting with proptosis: a case report.
Sang Hoon HYUN ; Young Mo KANG ; Chan Duck KIM ; Jong Myung LEE ; In Taek KIM ; Nung Soo KIM
Journal of Korean Medical Science 2000;15(2):247-250
Weber-Christian disease (WCD) is a rare inflammatory disease of adipose tissue, which is characterized by painful cutaneous nodules and constitutional symptoms. Although any area of the body containing fat can be affected by WCD, the involvement of retrobulbar fat is uncommon and proptosis is a rare presenting manifestation. We report a case who presented with proptosis of the right eye which is accompanied by painful subcutaneous nodules, high fever and myalgia. Biopsies of retrobulbar tissue and suprapubic nodule showed lobular panniculitis with mixed cellular infiltration, mainly composed of histiocytes and lymphocytes. He responded well to high-dose glucocorticoid.
Adult
;
Biopsy
;
Case Report
;
Exophthalmos/pathology*
;
Exophthalmos/etiology*
;
Exophthalmos/drug therapy
;
Glucocorticoids/administration & dosage
;
Human
;
Magnetic Resonance Imaging
;
Male
;
Panniculitis, Nodular Nonsuppurative/pathology*
;
Panniculitis, Nodular Nonsuppurative/drug therapy
;
Panniculitis, Nodular Nonsuppurative/complications*
7.Weber-Christian disease presenting with proptosis: a case report.
Sang Hoon HYUN ; Young Mo KANG ; Chan Duck KIM ; Jong Myung LEE ; In Taek KIM ; Nung Soo KIM
Journal of Korean Medical Science 2000;15(2):247-250
Weber-Christian disease (WCD) is a rare inflammatory disease of adipose tissue, which is characterized by painful cutaneous nodules and constitutional symptoms. Although any area of the body containing fat can be affected by WCD, the involvement of retrobulbar fat is uncommon and proptosis is a rare presenting manifestation. We report a case who presented with proptosis of the right eye which is accompanied by painful subcutaneous nodules, high fever and myalgia. Biopsies of retrobulbar tissue and suprapubic nodule showed lobular panniculitis with mixed cellular infiltration, mainly composed of histiocytes and lymphocytes. He responded well to high-dose glucocorticoid.
Adult
;
Biopsy
;
Case Report
;
Exophthalmos/pathology*
;
Exophthalmos/etiology*
;
Exophthalmos/drug therapy
;
Glucocorticoids/administration & dosage
;
Human
;
Magnetic Resonance Imaging
;
Male
;
Panniculitis, Nodular Nonsuppurative/pathology*
;
Panniculitis, Nodular Nonsuppurative/drug therapy
;
Panniculitis, Nodular Nonsuppurative/complications*
8.Two Cases of Weber-Christian Disease.
Chong Sang KIM ; Chang Woo LEE ; Hong Sik KIM
Korean Journal of Dermatology 1974;12(1):37-40
Two cases of Weber-Christian disease are reported. This very rare disease, we had two another reports of case sincc last ten years in The Korean Journal of Dermatology. In our cases both patients are seventeen years old girls and have the histories of remissions and exacerbations for two to three years. The skin lesions of subcutaneous nodules are scattered on the trunk, extremities and even to the hand dorsurns, with the atrophic depressions. Histologic features are typical with faormy histiocytes in the subcutaneous fat tissue. On tne treatments these patients are given oral corticosteroid, antihistaminics and salicylate with some improvments.
Depression
;
Dermatology
;
Extremities
;
Female
;
Hand
;
Histiocytes
;
Humans
;
Panniculitis, Nodular Nonsuppurative*
;
Rare Diseases
;
Skin
;
Subcutaneous Fat
9.A case of Weber-christian disease in a child.
Jong Hee NA ; Joon Hyeok YOON ; Do Won KIM ; Sang Lip CHUNG
Korean Journal of Dermatology 1993;31(1):109-113
Weber-Christian disease is an inflammatory disease of subcutneious fat tissue which is clinically characterized by relapsing, febrile, nodular, nonsuppurative pannicutilitiy. The cause is unknown, but the disease has been attributed to an autoimmune reaction, infectioris, halogen compounds, sarcoidosis, SLE and a-antitrypsin deficiency. We report here in a case of Weber-Christian disease in a 8-year-old girl, who had indurated erythemataus subcutaneous nodules on the extremities, buttock and trunk accompanied by various general symptoms such as fever, malaise, arthralgia and edema of the abclorren and legs. This case was successfully treated with dapsone,
Arthralgia
;
Buttocks
;
Child*
;
Dapsone
;
Edema
;
Extremities
;
Female
;
Fever
;
Humans
;
Leg
;
Panniculitis, Nodular Nonsuppurative*
;
Sarcoidosis
10.A Fatal Case of Weber-Christian Disease.
Young Ho WON ; Inn Ki CHUN ; Young Pio KIM
Korean Journal of Dermatology 1982;20(2):335-339
Weber-Christian diaease is characterized by recurrent crops of subcutaneous nodules or plaques which occur during febrile periods and usually has spontaneous regression. Since the earlier case reports there have been instances of nodular panniculitis affecting visceral fat as well as the subcutaneous tissue. Death may rarely occur follow ing visceral involvement. We experienced a fatal case of Weber-Christian disease in a 32 year old female, who had prominent hepatomegaly and leukopenia accompanied by various general symptoms such as nausea, vomiting, abdominal pain, and cough. This case also had unusually large erythematous swelling of the face and aMomen in addition to multiple subcutaneous nodules in the extremities and trunk.
Abdominal Pain
;
Adult
;
Cough
;
Extremities
;
Female
;
Hepatomegaly
;
Humans
;
Intra-Abdominal Fat
;
Leukopenia
;
Nausea
;
Panniculitis
;
Panniculitis, Nodular Nonsuppurative*
;
Subcutaneous Tissue
;
Vomiting