Objective:To investigate the effect and safety of Jinweitai combined with triple therapy in the treatment of gastric ul-cer. Methods:Totally 140 cases of gastric ulcer patients were randomly divided into two groups, group A was given clarithromycin, amoxicillin, bismuth pectin and pantoprazole in Hp eradication triple therapy, while group B was additionally given 0. 3g Jinweitai oral-ly, po,tid. The treatment course was 8 weeks. The effect was observed and compared. Results:Both the total effective rate and Hp e-radication rate of group B were higher than those of group A, the rate of mild inflammation and non-neutrophils infiltration after the treatment in group B were higher than those in group A (P<0. 05). The incidence of adverse reactions in the two groups was without statistical significance (P>0. 05). Conclusion:Base on the conventional Hp eradication triple therapy, Jinweitai can increase Hp e-radication rate and promote inflammation eliminate without extra adverse reactions in the treatment of gastric ulcer.

AIM: To explore the effects of axial stress regulation on healing of lengthened ca llus. METHODS: Tibiofibulars of 30 rabbits were lengthened 2 cm with t wice plane sreminobicular crib external fixator. Experimental group continues to lengthen 3 mm, and then were drawn and shortened 0.5mm once every 24 h separate ly for 10 days. Ten days later, tibiofibulars were axial short-stressed 1 mm wee kly with three times. Animals were killed 58 days after operation and X-ray, bon e density and histology tests were performed with lengthened bone. RESULTS: X-ray examination had no significant difference between two group animal when le ngthen ended, but X-ray showed lengthened callus was different on day 58. In con trol group, lengthened center had a serial callus and cortex had no formed, in experimental group, lengthened center had serial cortex and transfixial medullar y cavity expect serial callus. Bone density tests with two-energetic X-ray bone density measuring device showed bone density was higher in experimental group th an control group (P

No abstract available.

Objective: To study the correlation between the serum chemokine CXC Ligand 16 (CXCL16) levels or the CXCL16 gene rs3744700 polymorphisms and TOAST subtypes in patients with acute cerebral infarction. Methods: A total of 248 patients with atherosclerotic cerebral infarction within 7 days after symptom onset were selected, among them 149 patients were in a large artery atherosclerotic (LAA) cerebral infarction group, and 99 patients were in a small arterial occlusive (SAO) cerebral infarction group. The polymerase chain reaction (PCR) and gene sequencing were used to detect the genotypes. An enzyme-linked immunosorbent assay was used to detect the serum CXCL16 levels. Results: Circled digit oneSerum CXCL16 level in the LAA cerebral infarction group was 2.5 ± 0.3 μm/L and in the SAO cerebral infarction group were 2.3 ± 0.6 μg/L (P<0.01). Circled digit twoAmong the 149 patients in the LAA cerebral infarction group, the GG genotype frequency at polymorphic loci of CXCL16 gene rs3744700 was 91.9% (137/149) and the G allele frequency was 96.0% (286/298). They were higher than 81.8% and 89.9% in the SAO cerebral infarction group. There were significant differences (P < 0.05). Circled digit threeThe serum CXCL16 level in patients with CG genotype was 2.5 ± 0.3 μg/L in the LAA cerebral infarction group, ant it was higher than 2.1 ± 0.3 μg/L in patients with GT + TT genotype; the serum CXCL16 level in patients with CG genotype was 2.4 ± 0.6 μg/L in the SAO cerebral infarction group, and it was higher than 2.1 ± 0.3 μg/L in patients with GT + TT 2 genotype (all P < 0.01). Among the patients with GG genotype, the serum CXCL16 level in the LAA cerebral infarction group was higher than that in the SAO cerebral infarction group (P = 0.01); there was no significant difference in patients with GT + TT genotype between both groups. Circled digit fourMultivariate Logistic regression analysis showed that the serum CXCL16 level (OR =0.37, 95% CI 0.19 -0.70) and the GG genotype at polymorphic loci of CXCL16 gene rs3744700 (OR =2.57, 95% CI 1.23 -5.36) were the independent risk factors for affecting LAA cerebral infarction. Conclusion: In the TOAST subtypes, the correlation of serum CXCL16 level and the GG genotype at polymorphic loci of CXCL16 gene rs3744700 and LAA cerebral infarction are higher than SAO cerebral infarction.

ObjectiveTo investigate the effect of hyperbric oxygen (HBO) on infarct volume and relevant mechanism after permanent focal cerebral ischemia in adult rats.MethodsRat model of focal cerebral ischemia induced by intraluminal filament occlusion of middle cerebral artery (MCA) was used. HBO(2.0 ATA) was applied to HBO group. Infarct volume, matrix metalloproteinase 2 (MMP-2) and MMP-9 were detected at 6h, 24h, 48h, 72h,120h and 10d after ischemia.ResultsThe infarct volume obviously decreased at 120h and 10d and expression of MMP-9 lowered at 48—120h in HBO groups. There was no significant change in MMP-2.Conclusion HBO can reduce infarct volume after cerebral ischemia, which may be related to downregulation of MMP-9 levels.

Objective To develop a new methodology of prenatal sonography scoring to assess and dignose clubfoot.Methods Thirty-one fetuses suspected clubfoot(50 foots) and 62 normal fetuses(124 foots) were scanned with both 2D and 3D sonography,and were divided into normal feet group and clubfeet group.Our scoring system was made according to the Pirani-scoring for children,while considering the morphology of mid-foot and hind-foot of infants.The doctors would give final diagnosis for all fetuses after delivery or induced labor,and analyse the correlations among the abnormal signs,sonographic score and the clinical outcomes.Results The curve lat border,the medial crease,the empty heel and the post crease can be observed in the 3D reconstruction images.These four abnormal signs had close correlations with the clinical results.Conclusions The new prenatal clubfeet scoring system by 3D sonography is a promising methodology with clinical values.

Objective To investigate changes of thyroid function indices and their correlation with blood routine examination results, high-sensitivity c-reactive protein(hsCRP)levels and erythrocyte sedimentation rate(ESR)in 30 inpatients with acute urticaria. Methods Thyroid function indices were retrospectively analyzed in 30 inpatients with acute urticaria (patient group)and 30 healthy controls (control group), including total triiodothyronine (TT3), total thyroxine (TT4), free triiodothyronine (FT3), free thyroxine (FT4), thyroid-stimulating hormone (TSH), anti-thyroglobulin antibody(TG-Ab)and anti-thyroid peroxidase antibody(TPO-Ab). A correlation analysis was done between thyroid function indices and blood routine examination results (white blood cell [WBC]count, neutrophil count, hemoglobin), hsCRP levels and ESR. Results Abnormal thyroid function indices were observed in 23 (23/30, 76.7%) patients with acute urticaria. Compared with the control group, the patient group showed significantly decreased levels of FT3, TT3, TT4 and hemoglobin(t = 6.39, 5.55, 3.57, 3.70, all P < 0.01), but significantly increased positive rates of thyroid autoantibodies (χ2 = 7.68, P < 0.01)as well as WBC counts, neutrophil counts, hsCRP levels and ESR (t = 3.96, 8.73, 2.51, 2.35, all P < 0.05). There was a positive correlation between hemoglobin level and FT3, TT3, TT4 levels(r = 0.63, 0.59, 0.37, all P < 0.05), but a negative correlation between neutrophil count and FT3, TT3, TSH levels(r = -0.45,-0.50, -0.37, all P < 0.05), as well as between TT3 and hsCRP levels (r = -0.39, P < 0.05)in the patient group. Conclusion Patients with severe acute urticaria usually show abnormal thyroid function during attacks, which mainly manifests as low T3 syndrome and high positive rates of thyroid autoantibodies, and may be associated with decreased hemoglobin levels and infection.

Objective To study the adverse effects of outdoor air pollution on children's respiratory system health in Anshan city. Methods 1951 children were randomly selected from three areas with different degree of air pollution in Anshan city. The parents of the children were asked to answer a questionnaire about their children's respiratory health and home environment. The data of health were collected included persistent cough, persistent phlegm, asthma, current asthma, wheeze, and wheeze symptom. Results The prevalence rates of persistent cough, persistent phlegm, asthma, current asthma, wheeze and wheeze symptom were 9.48%, 4.82%, 1.33%, 0.92%, 6.30% and 4.97% respectively. Outdoor air pollution was a risk factor for persistent cough and persistent phlegm. The respiratory symptoms increased as the house became near to the main traffic lines. Combined effect of susceptible factor and outdoor air pollution was obvious, the prevalence rates of respiratory diseases were higher in the susceptible children who were influenced by the other risk factors compared with those who were not influenced by the same factors. Conclusion Outdoor air pollution is an important factor which will damage children's respiratory system in Anshan city.