Objective The facial soft tissue features were studied in Urumqi adolescent with skeletal Ⅱ malocclusion by using a polar coordinate system. Methods Sixty samples of Urumqi adolescent with skeletal Ⅱ malocclusion were selected, each one underwent cephalometrics analysis and 32 cephalometric parameters from the samples were measured. The mean and standard deviations of each measurement were compared by statistical analysis (t-test). Results Polar distance in male was larger than female, showing significant difference between male and female. Po-Ns/Po-Li, Po-Ns/Po-Bs, Po-Ns/PoPgs, Po-Ns/Po-Gns, and Po-Ns/Po-Mes showed significant difference between male and female. Polar angles in female were larger than male, with a significant difference between male and female.Conclusion Statisticalstudies on features of facial soft tissue show significant differences between male and female. The polar coordinate analysis system is a good index to study the growth magnititude and direction of facial soft tissue during growth and development or before treatment and after treatment.

Objective: To observe the clinical efficacy of electroacupuncture (EA) with different frequencies in treating migraine.Methods: Ninety patients with migraine were divided into a low frequency electroacupuncture (LF-EA) group, a high frequency electroacupuncture (HF-EA) group and a variable frequency electroacupuncture (VF-EA) group by the random number table method. Shuaigu (GB 8), Hegu (LI 4), Waiguan (TE 5), Taichong (LR 3), Taiyang (EX-HN 5), Fengchi (GB 20) and Ashi points were selected for all three groups. After achieving needling sensation (Deqi), the LF-EA group received 2 Hz continuous wave EA stimulation; the HF-EA group received 100 Hz continuous wave EA stimulation, and the VF-EA group received 2 Hz/100 Hz sparse-dense wave EA stimulation. The EA stimulation lasted for 30 min in all the three groups, once a day, 10 times as a course, and the clinical efficacy was evaluated after 2 consecutive courses of treatment. Results: After treatment, the total effective rates in the LF-EA group, HF-EA group and VF-EA group were 77.7％, 83.3％ and 93.3％, respectively. The difference in total effective rate between the LF-EA and HF-EA groups was not statistically significant (P>0.05), but the total effective rate was significantly higher in the VF-EA group than in the LF-EA and HF-EA groups (both P<0.01). After treatment, the headache scores significantly decreased in all three groups (all P<0.01). The difference in headache score between the LF-EA and HF-EA groups was not statistically significant (P>0.05), while the score was significantly lower in the VF-EA group than in the LF-EA and HF-EA groups (both P<0.01). Conclusion: VF-EA (2 Hz/100 Hz), compared with LF-EA (2 Hz) and HF-EA (100 Hz), shows superior clinical efficacy in treating migraine.

BACKGROUND:As an important cytokine, interleukin-6 regulates immune responses in inflammation sites and has an autocrine/paracrine activity that stimulates osteoclast formation and bone resorption, which is related to bone remodeling during orthodontic tooth movement.
OBJECTIVE:To investigate the effects of orthodontic force on the expression of interleukin-6 mRNA in the periodontal tissue of rats.
METHODS:In situ hybridization was performed to measure the expression of interleukin-6 mRNA at 1, 3, 5, 7, 10 and 14 days after the application of orthodontic force on the maxil ary first molars of rats.
RESULTS AND CONCLUSION:The expression of interleukin-6 mRNA was observed at a low level in the normal periodontal tissue of rats. After the application of force, the induction of interleukin-6 mRNA was observed to reach a maximum on day 3 and to decline thereafter. The expression of interleukin-6 mRNA can be evoked by orthodontic force but with a certain self-limiting. As a multifunctional cytokine, interleukin-6 plays a very important role in periodontal remodeling during orthodontic tooth movement.

Objective To discuss the application of Chinese version of Speech intelligibility rating (SIR) in e-valuating the speech intelligibility of Chinese children with hearing disorder ,and analyze its scorer reliability .Meth-ods 50 children with cochlear implants or hearing aids were interviewed using SRI Chinese version .Each child was rated by a parent and a speech and language therapist .The reliability of scores was analyzed with Spearman correla-tion coefficient ,Kendall's coefficient of concordance and Kappa coefficient .Results The complete agreement was foud in 34 cases(68% ) ,with a disagreement of one category in 14 cases(28% ) ,and a disagreement of 2 categories was found in 2 cases (4% ) .Spearman correlation coefficient was 0 .885 ,Kendall's coefficient of concordance was 0 .801 ,Kappa coeffi-cient was 0 .593 ,the result was statistically significant (P<0 .001) .Conclusion SRI Chinese version has good reliability and is helpful in evaluating Chinese speech producing ability of children with hearing disorder in everyday life .

Objective To investigate the influence of stroke volume variation (SVV)-guided fluid therapy on postoperative cognitive function in elderly patients undergoing the unilateral total knee arthroplasty(UTKA).Methods One hundred patients undergoing the UTKA were randomly di-vided into two groups,group A(SVV 4%-9%)and group B(SVV 10%-14%).The liquid manage-ment,serum markers (CRP,IL-6)and the incidences of deflating-tourniquet-related hypotension and preoperative, 5 d after surgery of the occurrence of POCD in two groups were recorded. Results There was no significant difference in general information between the two groups. Compared with group B,group A needed more fluid transfusion and had a higher 24 h urine volume. The CRP and IL-6 was significantly higher in group B than that in group A;The incidence of defla-ting-tourniquet-related hypotension in group A [22(44%)]was also lower than that in group B [43 (86%)].However,there was no significant difference in the incidence of POCD between the two groups.Conclusion Sufficient blood volume can help to reduce the incidence of deflating-tourniquet-related hypotension,and reduce the inflammatory reaction in elderly patients.

Objective To study the effect of multi-disciplinary teamwork (MDT) nursing mode on perioperative care to breast cancer patients. Methods One hundred and twenty breast cancer patients undergoing surgical operations were evenly randomized into the observation and control groups by random digit number table. The control group was treated with routine nursing care and the observation group with MDT nursing mode. Result The rate of complications (like subcutaneous effusion, lymphatic edema and skin flap necrosis) in the observation group was significantly lower than that of the control group and the hospital stay was significantly shorter than that of the control group as well (all P<0.05). Conclusion The MDT nursing mode can reduce the rate of complications, shorten the hospital stay and relieve patient′s depression.

BACKGROUND:It is very important to appreciate the Sagittal discrepancy during the diagnosis and therapy in orthodontics patients.At present,ANB angle,AXB angle,Beta angle and APDI value were often used to evaluate the mandible and maxilla relationships in orthodontic clinic.Correlation and variance degree among these parameters were analyzed to judge the reliability.OBJECTIVE:To compare the reliability of ANB angle,AXB angle,Beta angle and APDI value in assessing sagittal discrepancy between mandible and maxilla in transitional dentition cases with Angle's class Ⅲ malocclusion.METHODS:Totally 56 patients of Angle's class Ⅲ malocclusion in transitional dentition at the Department of Orthodontics,First Affiliated Hospital of Xinjiang Medical University,between January 2004 and June 2009,were selected.ANB angle,AXB angle,Beta angle and APDI value of Angle's class Ⅲ malocclusion in transitional dentition were measured on the cephalometric radiographs.The radiographs were scanned by Microtek Phantom 9800 XL scanner at proportion of 1:1 with 300 dpi pixels,and saved as JPG format.The JPG pictures were fixed-point using Photoshop 8.0 to measure ANB angle,AXB angle,Beta angle and APDI value,the mean value was obtained after 3 times measurement.The correlation and variance degree among these parameters were analyzed.RESULTS AND CONCLUSION:Significant correlation was found among ANB angle,AXB angle,Beta angle and APDI value (P＜0.05).The coefficients of variation for the 4 indexes were 1.35,0.75,0.07 and 0.04,respectively.The results demonstrated that,it is accurate to use ANB angle,AXB angle,Beta angle and APDI value as cephalometric norm to evaluate sagittal discrepancy of maxmandibul in transitional dentition cases with Angle's class Ⅲ malocclusion.However,the APDI value is more reliable as cephalometric norm.

BACKGROUND:Beta angle,as a new index for the assessment of sagittal jaw relationship,has been widely used by clinical doctors.However,hand-made measurement but not academic software is still adopted in some hospital.OBJECTIVE:To study the beta angle of different skeletal patterns in Urumqi city for the clinical use of the method to assess the sagittal jaw relationship,and verify the possibility of Photoshop software to measurement of beta angle.DESIGN,TIME AND SETTING:An observational experiment and measurement design was performed at Department of Orthodontics,the First Affiliated Hospital of Xinjiang Medical University from July 2006 to May 2009.PARTICIPANTS:A total of 262 malocclusion cases including 94 males and 168 females were lived in Urumqi City.They were divided into three groups based on type of facies ossea,including type Ⅰ group (n=119),type Ⅱ group (n=74),and type Ⅲ group (n=69).METHODS:Lateral position of skull was photographed using X-ray,and beta angle was measured using Photoshop 8.0 software.Sex and type of facies ossea were compared using one-way analysis of variance and t test.MAIN OUTCOME MEASURE:Beta angle of male and female;beta angle of the types Ⅰ,Ⅱ,and Ⅲ.RESULT:There was no significant difference in beta angle between males and females (P>0.05).Beta angle of type Ⅰ was (34.15±3.88)°,that of type Ⅱ was (26.42±2.65)°,and that of type Ⅲ was 42.41°±1.88°.There was significant difference in beta angle among three types of facies ossea (P<0.01).CONCLUSION:Beta angle is an index for the assessment of sagittal jaw relationship.The reference range of the beta angle is 30°-38°.Photoshop 8.0 software is a novel tool to measure cephalometry.

Objective To investigate the prevalence of multidrug resistant genes in Klebsiella pncumoniae.MethodsTwenty strains of multidrug resistant Klebsiella pneumoniae were isolated from burn patients.Susceptibility of these strains to 14 antibiotics was detected by KB method.PCR was used to detect oqxA,smrKpn,qacE,tehA,mdfA and qacEΔl-sul1 genes.ResultsThe antibiotic sensitivity rates of 20 multidrug resistant Klebsiella pneumoniae isolates to antibiotics tested were ＜ 30％ except that to imipenam.The positive rates of efflux pump genes mdfA,qacEΔl-sull and oqxA were 65％,100％ and 100％,respectively; while those ofsmrKpn,qacE and tehA were 0％,0％ and 15％.ConclusionoqxA gene has been detected in multidrug resistant Klebsiella pneumoniae from burn patients with high positive rate.

OBJECTIVE To investigate drug resistant genes associated with beta-lactamases,aminoglycosides and sulfonamides in Pseudomonas aeruginosa isolated from burned patients.METHODS Common drug resistant genes associated with beta-lactamases,aminoglycosides and sulfonamides of 20 strains of P.aeruginosa isolated from burned patients were detected by PCR.RESULTS The positive rates of genes of TEM,aac(6′)-Ⅰb,sul1 and ant(3″)-Ⅰwere 85%,85%,90% and 10%,respectively and genes of CARB and aac(6′)-Ⅱ were both positive(100%).Genes of oprD2 were all absent and genes of SHV,GES,IMP,VIM,DHA and armA were all negative.Furthermore,drug resistant genes of strains isolated from different sites of one patient on different time could be different.CONCLUSIONS Drug resistant genes of CARB and aac(6′)-Ⅱprevail in P.aeruginosa isolated from burned patients.Detections of drug resistant genes in P.aeruginosa isolated,especially continuously isolated from burned patients are essential.