1.Cardiac Magnetic Resonance Scar Imaging for Sudden Cardiac Death Risk Stratification in Patients with Non-Ischemic Cardiomyopathy.
Eun Kyoung KIM ; Pairoj CHATTRANUKULCHAI ; Igor KLEM
Korean Journal of Radiology 2015;16(4):683-695
In patients with non-ischemic cardiomyopathy (NICM), risk stratification for sudden cardiac death (SCD) and selection of patients who would benefit from prophylactic implantable cardioverter-defibrillators remains challenging. We aim to discuss the evidence of cardiac magnetic resonance (CMR)-derived myocardial scar for the prediction of adverse cardiovascular outcomes in NICM. From the 15 studies analyzed, with a total of 2747 patients, the average prevalence of myocardial scar was 41%. In patients with myocardial scar, the risk for adverse cardiac events was more than 3-fold higher, and risk for arrhythmic events 5-fold higher, as compared to patients without scar. Based on the available observational, single center studies, CMR scar assessment may be a promising new tool for SCD risk stratification, which merits further investigation.
Arrhythmias, Cardiac/*diagnosis
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Cardiomyopathies/*diagnosis
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Cicatrix/*diagnosis
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Death, Sudden, Cardiac
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Defibrillators, Implantable
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Female
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Humans
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Magnetic Resonance Imaging, Cine/*methods
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Myocardium/pathology
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Risk Assessment
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Risk Factors