No abstract available.
Breast ; Paget's Disease, Mammary*

No abstract available.
Paget's Disease, Mammary*

No abstract available.
Nipples* ; Paget's Disease, Mammary*

No abstract available.
Dermoscopy* ; Nipples* ; Paget's Disease, Mammary*

Pigmented mammary Paget disease is a very rare clinicopathologic variant of mammary Paget disease. Diagnosis is often difficult because its clinical and histological features are very similar to those of malignant melanoma. Herein, we report a case of pigmented mammary Paget disease misdiagnosed as malignant melanoma.
Diagnosis ; Melanoma* ; Paget's Disease, Mammary*

Sir James Paget described the first case of Paget's disease of the breast in 1874, and Du-breuilh, in 1901, reported the first case of extramammary Paget's disease of the vulva. Paget's disease of vulva is a rare intraepithelial neoplasm of uncertain histogenesis. Recently we expe-rienced a case of Paget's disease of the vulva that we present a brief review of literature.
Carcinoma in Situ ; Paget Disease, Extramammary ; Paget's Disease, Mammary ; Vulva*

Pigmented mammary Paget disease (PMPD) is a rare subtype of mammary Paget disease that presents as a hyperpigmented patch or plaque over the areola and nipple. We herein report on an unusual case of PMPD with reticulated features in a 98-year-old female. The histology showed intraepidermal pagetoid cells containing melanin pigments without any underlying intraductal carcinoma.
Carcinoma, Intraductal, Noninfiltrating ; Female ; Humans ; Melanins ; Nipples ; Paget's Disease, Mammary

PURPOSE: To evaluate the significance of mammographic findings in patients with paget's disease of the breast. MATERIALS AND METHODS: The clinical and mammographic records of ten patients with surgically-proved paget disease of the breast were retrospectively reviewed. RESULTS: Of these ten patients, the mammograms of two(20%) were normal, while those of six(60%) showed nipple or subareolar abnormalities, and those of six(60%) showed parenchymal abnormalities. Of six patients who had nipple change only, the mammograms of four showed nipple orsubareolar abnormalities and those of three showed parenchymal abnormalities. Of two patients who had nipple change and palpable mass, the mammograms of both showed nipple or subareolar and parenchymal abnormalities. Of two patients who had palpable mass only, the mammograms of both failed to show nipple or subareolar abnormalities and those of one showed parenchymal abnormalities. CONCLUSION: In Paget's disease of the breast, mammographic findings are nonspecific and are limited to an evaluation of the extension of the primary carcinoma. Therefore clinical findings should be correlated with mammographic findings.
Breast ; Humans ; Nipples ; Paget's Disease, Mammary* ; Retrospective Studies

Extramammary Pagets disease(EMPD) of the vulva is an uncommon neoplasm which accounting for 2.5% of all vulvar malignancies and 0.02% of all female cancer. Several hundred cases have been reported worldwide since the first description by sir James Paget in 1874, It generally affects postrnenopausal age poup and presents high rate of recurrence but the precise incidence remines unclear, Although Paget's disease of the breast and the vulva are histologically similar, their histogenesis and biological behavior are considered to be significantly different and EMPD has gcnerally perceived rnore benign compared to that of the breast. Four histologic forms of vulvar EMPD have been recognized and treated vulvar EMPD in according to the 4 histologic classification. The high rate of recurtence disease remains a challenge for optimal management. Recently we experienced a case of Paget's disease of the vulva, diagnosed as an intraepithelial Pagets disease preoperatively and underwent radical vulvectomy and superiomedial thigh(SMT) flap, and present with a brief review of literature.
Breast ; Classification ; Female ; Humans ; Incidence ; Paget's Disease, Mammary ; Recurrence ; Vulva*

Extramammary Paget's disease(EMPD), like primary Paget's disease of the nipple, is characterized by initial growth of malignant adenocarcinoma cells within the epidermis. It may be accompanied by an invasive adenocarcinoma or in situ adenocarcinoma of the apocrine gland. The lesion is a rare tumor that most frequently involves the vulva or anus, and the involvement of the penis and scrotum is extremely rare. It can be managed by local excision and immediate reconstruction with skin grafting or a local skin flap. We review the literature and report a case of extramammary Paget's disease with apocrine adenocarcinoma of the penis and scrotum.
Adenocarcinoma* ; Anal Canal ; Apocrine Glands ; Epidermis ; Male ; Paget Disease, Extramammary* ; Paget's Disease, Mammary ; Penis* ; Scrotum* ; Skin ; Skin Transplantation ; Vulva