1.Trends of case detection and other indicators of leprosy in China during 1985-2002.
Jian-ping SHEN ; M D GUPTE ; Cheng JIANG ; P MANICKAM ; Mei-wen YU ; Wen-zhong LI
Chinese Medical Sciences Journal 2005;20(2):77-82
<p>OBJECTIVETo analyze the trends of case detection and other indicators of leprosy in China during 1985-2002.p><p>METHODSData reported by each province were collected by China National Leprosy Database in Nanjing P.R. China. All data about registered cases were put into computer for analysis.p><p>RESULTSFrom 1985 to 2002, a total of 49,477 new leprosy cases had been detected. Among them, 69.5% were multibacillary cases and 25.4% had grade 2 disability. The child cases aged below 15 years accounted for 3.74% of total cases. Totally, 5824 cases and 303 cases relapsed after dapsone (DDS) mono-therapy and multidrug therapy (MDT), respectively. Case detection showed a marked reduction from 0.47/100,000 in 1985 to 0.18/100,000 in 1993 although there were several spurts due to operational factors. From 1994, case detection showed no significant decline. The grade 2 disability among new patients decreased from 31.4% in 1985 to 23.4% in 2002. The child case detection rate among new cases fluctuated between 2.70%-3.56% from 1999 to 2002. The incidence of relapse declined after the introduction of DDS mono-therapy. However, it increased after the introduction of MDT.p><p>CONCLUSIONChina experiences in leprosy control show that it will take a long time with continuing present leprosy control activities to bring down the case detection and other indicators to a very low level even after reaching the elimination goal of leprosy.p>
Adolescent
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Adult
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Age Factors
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Child
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China
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epidemiology
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Communicable Disease Control
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trends
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Dapsone
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administration & dosage
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therapeutic use
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Disability Evaluation
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Drug Therapy, Combination
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Humans
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Incidence
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Leprostatic Agents
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administration & dosage
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therapeutic use
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Leprosy
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drug therapy
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epidemiology
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prevention & control
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Recurrence