1.Studies on chemical and bacterial contamination of soil in Ulaanbaatar
Mongolian Medical Sciences 2016;178(4):61-67
The results of studies on heavy metal and bacterial contamination in Ulaanbaatar since 1990 have beensummed up in this abstract. In the recent years, soil pollution has increased due to rising number ofpopulation, especially in ger districts, factories and services in Ulaanbaatar. According to some surveys,pollution indicators of lead, arsenic and bacterial contamination in soil have exceedednationalstandardlevel.
2.The Hygienic Assessment of Secondary School of Organization of Teaching and Educational Activity, Chemical and Bacterial Contamination On Teaching Environment
Amardulam N ; Burmaajav B ; Kupul J ; Amgalan G ; Baigali O ; Oyunchimeg M
Mongolian Medical Sciences 2010;151(1):8-11
NEED FOR STUDY AND GOAL: There is no data available on pupil’s health with relation to the school environmental condition and organization of educational activities in Mongolia. Therefore, the goal of the study was to assess organization of the educational activities and conduct hygienic assessment of chemical and bacteriological contamination in the school environment.MATERIALS AND METHODS: A total of 1440 children were surveyed in this cross sectional study from the 6 secondary schools of UB city, Uvurhangai and Dornod aimags.Hygiene conditions of school was assessed and organization of educational activities evaluated by class timetable and pupil’s notes of daily regime.RESULT: Timetable of lessons: It was observed that in some cases teachers’ taught to primary pupils Mathematics and Mongolian language for 2 sequential hours, depending on some indexes such as lesson content, capacity and student’s activity. According to timetable of lessons of the secondary schools, pupils have lessons for 32-34 hours in a week. It was revealed that most schools have 2-3 hours more than standard timetable and heavy lessons were taught for 2-3 sequential hours. For the secondary classes, average length of classes was 32-34 hours in a week which indicates 2-3 hours longer timetable. There was no special place for physical training and movement games etc where pupil can do physical exercise, relax and enjoy school life. DAILY REGIME: pupils have been spending most of their time watching TV and listening music and spending few hours to help housework, to read a book and to prepare meal. Urban pupils spent total of 0.5-1 hour for coming to school and going to home but rural pupils spent 20-30 minutes approximately. RESULT OF THE LABORATORY ANALYSIS: The bacteriological analysis of 36 classes in schools showed that before lesson, 94.4% of classes were clean while 5.6% was contaminated in first season of school year. After the lesson, percentage of classes without contamination had been dropped to 88.8% and classes with contamination had been increased to 11.2%. In the 4th season of school year, before lesson 61.6% of classes was clean and 16.6% was contaminated and 22.3% was highly contaminated. Moreover, after the lesson, classes without contamination had been dropped to 27.7% while 72.3% was at high level contamination.CONCLUSION: 1. Time table of lessons and break time management is inadequate in the schools and 32-39.1% of pupils do not follow the daily regime. 2. In the end of day, chemical and bacteriological contamination increased in the classes.
3.Results of Study of Mongolian Pupil’s Learning Abilities
Amgalan G ; Burmaajav B ; Kupul J ; Amardulam N ; Baigali O ; Oyunchimeg M
Mongolian Medical Sciences 2010;151(1):12-16
INTRODUSTION: There have been limited research studies done in Mongolia on health status of children in relation to density of children in school classrooms.GOAL: This study aims to evaluate learning ability of children in Mongolia and develop recommendations for next intervention measures.MATERIALS AN METHODS: A total of 1440 children were surveyed in a cross sectional study that included 6 classes from 6 secondary schools of UB city, Uvurhangai and Dornod aimags. The test of letter drawing created by of V.Ya.Anfi mova was used to evaluate the pupil’s learning skills. This test was performed at the fi rst and last classes in each day of which was tested at the beginning (I quarter or September) and end (IV quarter or May) of the academic year.For each tests we accounted the mean of drawing letter, mean of mistake for 500 letter and standard deviation.RESULTS: The results of pupil’s letter drawing tests were compared by quarter for fi rst and last classes in each day. Pupil’s learning ability of class 4 was enough while other classes were not enough (P index 1) on the fi rst and last tests.CONCLUSION: Pupil’s learning ability has been changed by the same way of physiological adaptation process of child.Pupil’s learning ability had been decreased in last tests of each day and on Friday which was revealed by letter drawing test.Pupil’s learning ability of classes between 4 to 9 were not enough on the fi rst term while 4th class was good enough on the forth term (P index 1).
4.Findings of study of knowledge and attitude on health promoting workplaces of Khentii aimag
Orkhonchimeg N ; Saijaa N ; Oyunchimeg M ; Bujinlkham B ; Dashnamjilmaa D ; Tsendjav J ; Alimaa G
Mongolian Medical Sciences 2013;163(1):62-66
BackgroundThe target group of the project, working age population, is more vulnerably exposed to the risk factors of NCDs due to deficiency of physical activities, stress, unhealthy eating, etc. The current study was carried out to assess the knowledge and attitude on health promoting workplaces among the employees of public and non-governmental organizations and businesses operating in Kherlen soum of Khentii aimag, identify their needs and make conclusions.Materials and MethodsThe cross-sectional study used questionnaires for 195 employees of 10 public agencies and 3 business entities of Kherlen soum of Khentii aimag, focus group discussions among 32 employees and individual interviews with 13 managing officials.ResultsWomen composed 38% (74 persons) and men composed 62% (121 persons) of the participants of the study. As for the duration of the service, 115 people or 58.7% have served for 1-10 years, 49 people or 25% have served for 11-20 years, 21 persons or 10.7% have served for 21-30 years and 6 persons or 3.1% have worked for 30 years. As for the knowledge of health promoting workplaces, the absolute majority of the participants demonstrated medium or low level of knowledge with statistical significance (p<0.01) among ages, with women demonstrating higher level of knowledge and increasing trend with the years of work. Absolute majority of the participants of the qualitative survey answered that possess insufficient information of health promoting workplaces. Majority or 54.2% (105) of the participants understand health promoting workplaces as provision of working conditions and organization of preventive health check ups. Creating healthy workplaces will have no negativeimpact but increased productivity, higher morale, better wellness, according to the respondents. Job satisfaction as an impact of health promotion at workplace was supported by 48.4% of the employees at 20-30 years age and 54.2% of the employees who have served for 11-20 years. 57.7% (112) of the respondents disagree that their workplaces created health promoting conditions. The knowledge of the majority of the participants in insufficient as 89.3% answer that WHP is provision of healthy environment for working. Health promotion is not implemented sufficiently at the policy level and is limited merely to improvement of physical environment and solution of social problems, with insufficient behavior targeting actions and participation of employees in health promoting activities.Conclusions:1. The knowledge on health promoting workplaces is insufficient.2. The answers of the respondents that lack of health promotion at workplaces will reduce productivity (69.2%) and adversely affect the health of the employees (44.7%) demonstrate the need in WHP.3. The further activities necessary for further development of health promoting workplaces were identified as provision of comprehensive knowledge, cooperation with professional organizations and learn from experiences of health promoting workplace models, mutual learning and solution of the financial issues.
5.Relationship between respiratory and circulatory diseases among adults and air temperature
Nyam-Osor D ; Oyunchimeg M ; Nyamsuren L ; Amgalan G ; Enkhtuya P ; Burmaajav B
Mongolian Medical Sciences 2012;162(4):36-42
BackgroundHuman-induced climate change will affect the lives of most populations in the next decade and beyond. The impact of meteorological conditions on human health has been reported globally. There is a need to conduct surveys for correlation between climate change and human health.GoalTo study the impact of air temperature on human health in selected aimags and city districts.Materials and MethodsIn order to study how climate change and air quality parameters affect human health we selected Zavhan, Selenge, Dornod, and Umnugobi aimags which represent different climate zones and 2 districts of Ulaanbaatar city during 2009-2011. All data for respiratory system disease J00-J99, circulatory system disease I00-I99, were collected from soum, district’s hospital, and aimag and soum’s Department of health.ResultsDuring the study period, a total number of 8649 incidences of respiratory disease are registered. From them 74.2 percent are influenza and pneumonia (J09-J18), 17.6 percent are other acute lower respiratory infections (J20- J22), and 8.2 percent are asthma (J45-J45.9). For cardiovascular disease 15288 incidences are registered. From them 65.6 percent are hypertensive disease (I10-I15), 23.6 percent are ischemic heart disease, and 10.8 percent are cerebrovascular diseases (I60-I69). The lower the air temperature, higher the incidence of influenza and pneumonia, acute lower respiratory infections, hypertensive, and ischemic heart disease.ConclusionsCold weather is correlated with a higher incidence of respiratory and cardiovascular diseases.
6.Health Impact Assessment of the Mining Industry
Oyunchimeg M ; Suvd B ; Enkhjargal A ; Burmaajav B
Mongolian Medical Sciences 2023;203(1):66-79
Health impact assessment is a means of evidence-based policy-making for improvement in health. It is a combination of methods whose aim is to assess the health consequences to a population of a policy, project, or program that does not necessarily have health as its primary objective. It is described as being “the leading global network on best practice in the use of impact assessment for informed decision-making regarding policies, programs, plans and projects”. In recent years, much evidence was revealed that the mining, metal mining, and processing industry has a greatly impact on humans. Residing population has affected directly and indirectly influenced to the health and wellbeing of human.
The mining, metal mining and processing industries play an important role in the economic and social development of Mongolia. With the rapid development of the mining industry in Mongolia, environmental protection and environmental rehabilitation have become a priority. Currently, there are 27 laws governing environmental legal acts in our country, and chapter 3 of the Hygiene Law covers environmental and health impact assessment. As stated the implementation of the law shall be financed from the state and local budgets, the central state administrative organization and the Governor at the appropriate level shall order the relevant professional organizations to carry out environmental research and analysis work and to develop projects, and in addition to financing with budget funds, as well as conducting research with their funds for interested citizens, enterprises, and organizations were are arrangements to support the implementation of the laws and its regulation.
However, Within the scope of the Law on Environmental Protection and Detailed Environmental Impact Assessment Procedures, the negative impact on the environment is identified but in the area of health impact, it is a lack of information on how the activities are conducted, and health impact assessments are not conducted according to procedures and methods. Thus, there are need to conduct health impact assessments of the mining area and its affected population.
7.Biochemical and pharmacological studies of bovine liver hydrolysate
Oyunchimeg B ; Bayanmunkh A ; Davaasambuu T ; Chimegee TS ; Sosorburam B ; Narangerel B ; Lkhagva L ; Khurelbaatar L ; Bayarjargal M ; Gan-Erdene T
Mongolian Medical Sciences 2013;164(2):82-88
BackgroundPreliminary clinical studies indicate that liver extract may be helpful in treating hepatic dysfunction. In addition, liver extract seems to work synergistically with interferon in treating hepatitis C and other viral infections. Laboratory studies indicate that liver extract may have some effects that could be useful in treating certain forms of cancer, such as ability to direct migration of metastasizing cells and inhibition of DNA, RNA and protein formation. More research is needed in these areas to determine liver hydrolysate’s properties.Materials and MethodsSeveral biochemical methods were used for determination of chemical compounds in liver extracts: Total protein and nitrogen content was determined by Kjeldahl method; mineral contents – atomic absorption spectrophotometer; Heme iron content – spectrophotometer; Water soluble vitamins - HPLC method. The pharmacological activities of bovine liver were tested by several pharmacological methods: Acute toxicity – LD50 /Prozorovskii 1978/; Acute hepatitis – Carbon tetrachloride (CCl4) induced liver damage in rats /Skakun et al, 1984/; Biochemical parameters in blood serum – Automatic biochemical analyzer.ResultThe values obtained in determination of the biochemical analysis show that 100 g consumption of studied liver hydrolysate can provide 4.3, 2.1 and 0.3 mg vitamin B1, B3 and B9 respectively. Therefore, present data reveal that liver hydrolysate is a good source of most of the analyzed minerals. The liver hydrolysate contains 56.4% total protein and 4.33% amino nutrient.Conclusions:1. From the results of pharmacological study that involves CCl4 induced acute toxic hepatitis, liver hydrolysate has hepatoprotective effect by protecting the liver cells from injury, improving the regeneration process and by correcting metabolic functions of the liver.2. When tested, hydrolysate’s pharmacological parameters can be analyzed reliably with several liver damage experimental designs, further improvements or the use of new designs such as anemia is needed in further pharmacological study.
8.Results of the study of the pharmacological action of the liver hydrolyzate
Davaasambuu T ; Oyunchimeg B ; Chimegee TS ; Sosorburam B ; Narangerel B ; Ganbold D ; Lkhagva L ; Khurelbaatar L ; Bayarjargal M ; Gan-Erdene T
Mongolian Medical Sciences 2012;162(4):78-85
BackgroundLiver protecting effect of liver hydrolysate is studied on CCl4 induced by acute toxic hepatitis on rats compared with “Raw Liver Glandular” which is similar product of “Swanson”, USA. Result was confirmed with histological study.Materials and MethodsCarbon tetrachloride-CCl4 is considered as a direct hepatotoxin which produces centri-lobular necrosis and steatosis. The mechanism of acute toxic hepatitis induced by CCl4 involves lipid peroxidation of membrane bound fatty acids which result in destructing the cell membrane and the intracellular organells of the hepatocyte.Result:As study result, after 7 days CCL4 exposure, experimental group’s serum ALAT (p<0.01), GGT (p<0.05) and ALP (p<0.05) levels decreased rapidly compared with control groups.ConclusionAlthough, liver hydrolysate is not medicine for treatment liver damage, it might be improved regeneration process in the damaged liver cells. As result, histomorphological study came to the following conclusion: in the seventh day of the model of acute toxic hepatitis of the liver in rats, cytoplasm vacuoles of hepatocytes were decreased sharply, hepatocytes became multilateral, “Kupffer cells” were increased, young hepatocytes were streamlined as columnar-cells, capillaries were became visible and was began regeneration. There were reported that bovine and pork protein hydrolysate contains essential amino acids with antioxidant effect which prevents liver cells from oxidative stress. Besides it, liver hydrolysate containing amino acids, vitamin B1, B6, folic acid and some minerals improves metabolism and regeneration process of damaged liver cells.
9.Estimated glomerular filtration rate in alcohol use disorder people
Khorolgarav A ; Narantsatsral D ; Oyundelger M ; Zoljargal S ; Oyunchimeg D ; Erdenebat N
Diagnosis 2025;112(1):5-9
Background:
The purpose of this study is to evaluate serum creatinine as a marker of estimated glomerular filtration rate (eGFR) in alcohol use disorder people, and to determine correlation between mean arterial pressure (MAP) and eGFR in chronic kidney disease classification level.
Methods:
In this study, 118 people were examined 2024. We measured serum creatinine based GFR using the Cockroft Gault formula. Biochemical analysis and serum creatinine were evaluated using a fully automatic analyzer (GOLSITE, China). Statistical results were analyzed SPSS.
Result:
The mean subject age was 48.6±10.3, BMI 25.3±3.7 and male: female ratio was 5:1. Mean arterial pressure was 104±12.8 mmHg, eGFR 94±28 ml/ min/1.73m2, and mean arterial pressure was significantly correlated with estimated glomerular filtration rate (P<0.05) and no difference between male and female recipients. Mean eGFR was calculated into 4 groups of 10-year intervals, that eGFR was decreased significantly with age groups. For the alcohol dependence stages of the Michigan Test, the mean eGFR was stage 1 is 112 ml/min/1.73m2, stage 2 is 89 ml/min/1.73m2, stage 3 is 97 ml/min/1.73m2 and there is not statistically significant correlation between Michigan test scores and eGFR.
Conclusion
According to our research, one of the optimal methods for assessing kidney function is the creatinine-based CKD calculation method, and long-term excessive alcohol consumption is a risk factor for CKD, as well as one of the main causes of death due to hypertension and cardiovascular disease.
10.Evaluation of some changes in liver function in patients with alcohol use disorder
Udmaral B ; Byambajargal D ; Pagmadulam B ; Oyundelger M ; Zoljargal S ; Oyunchimeg D ; Erdenebat N
Diagnosis 2025;112(1):75-79
Background:
To evaluate changes in liver function in patients with alcohol use disorder and propose preventive measures.
Methods:
In this study, 118 people were examined between January 2024 to December 2024. Results were analyzed SPSS.
Result:
The mean subject age was 48.6± 10.3 years, male: female ratio was 5:1. Mean arterial pressure was 104±12.8 mmHg, ALT 86.7 ± 93.8 (U/L), AST 89.3±82.8 (U/L), GGT 213.8±252.3 (U/L). A statistically
significant correlation was found between AST and ALT levels (R² = 0.562). However, no significant correlation was observed between body mass index (BMI) and blood glucose levels (R² = 0.002). The AST/ALT ratio was also statistically significant (p = 0.0001).
Conclusion
Excessive alcohol consumption increases the levels of liver enzymes AST 89.3 ± 82.8 (U/L), ALT 86.7
± 93.8 (U/L), and GGT 213.8 ± 252.3 (U/L), leading to increased liver cell damage. Therefore, it is necessary to reduce alcohol consumption and implement preventive measures.