No abstract available.
Blood Pressure ; Oxygen

No abstract available.
Fetal Blood* ; Humans* ; Oxygen* ; Phagocytes*

BACKGROUND:This study was designed to compare hydroxyethylstarch (HES) to albumin in high-risk surgery patients infused over 72 h peri-operatively; hemodynamic changes, oxygen transport parameters, blood gases, blood coagulation, blood loss, blood use, outcome, and costs were compared. METHODS:High-risk surgical patients undergoing high-risk abdominal, cranial, and orthopaedic surgery were treated with 6% HES (130/0.4; n = 41) or 20% albumin (n = 19).The goal of volume therapy was to maintain a normal cardiac index (CI; 3.0 L/min/m2) over 72 h peri-operatively. RESULTS:The hemodynamic and cardiac effects of 6% HES were superior to 20% albumin.HES reduced disturbances in blood coagulation, blood loss, and blood use as compared to albumin. Volume therapy with HES and albumin improved patient outcomes.Use of HES resulted in a significant cost reduction compared to albumin. CONCLUSIONS:Volume replacement with 6% HES and 20% albumin in surgery over 72 h peri-operatively improved hemodynamic parameters and oxygen transport to normal values.HES provides a cost-effective alternative to albumin in surgery with improved efficacy and safety.
Blood Coagulation ; Gases ; Hemodynamics ; Humans ; Orthopedics ; Oxygen

BACKGROUND:This study was designed to compare hydroxyethylstarch (HES) to albumin in high-risk surgery patients infused over 72 h peri-operatively; hemodynamic changes, oxygen transport parameters, blood gases, blood coagulation, blood loss, blood use, outcome, and costs were compared. METHODS:High-risk surgical patients undergoing high-risk abdominal, cranial, and orthopaedic surgery were treated with 6% HES (130/0.4; n = 41) or 20% albumin (n = 19).The goal of volume therapy was to maintain a normal cardiac index (CI; 3.0 L/min/m2) over 72 h peri-operatively. RESULTS:The hemodynamic and cardiac effects of 6% HES were superior to 20% albumin.HES reduced disturbances in blood coagulation, blood loss, and blood use as compared to albumin. Volume therapy with HES and albumin improved patient outcomes.Use of HES resulted in a significant cost reduction compared to albumin. CONCLUSIONS:Volume replacement with 6% HES and 20% albumin in surgery over 72 h peri-operatively improved hemodynamic parameters and oxygen transport to normal values.HES provides a cost-effective alternative to albumin in surgery with improved efficacy and safety.
Blood Coagulation ; Gases ; Hemodynamics ; Humans ; Orthopedics ; Oxygen

Humans ; Infant, Extremely Premature ; blood ; Infant, Newborn ; Oxygen ; blood

OBJECTIVETo investigate the relationship between blood nitrogen monoxide(NO) and PaO2 or PaCO2 levels in patients with severe and moderate acute carbon monoxide poisoning.

METHODThe blood levels of NO in patients with severe and moderate acute carbon monoxide poisoning was assayed with nitrate reductase method, and its correlation with the blood levels of PaO2 and PaCO2 was analyzed.

RESULTSThe blood level of NO in patients with severe and moderate acute carbon monoxide poisoning were (36.6 +/- 9.9) and (35.7 +/- 10.7) mumol/L respectively, significantly lower than that of control group[(64.9 +/- 14.3) mumol/L, P < 0.01], but there was no significant difference between moderate and severe patients(P > 0.05). The analysis of linear correlation showed that there was significant positive correlation between NO and PaO2 but not PaCO2.

CONCLUSIONAnoxia of patients with acute carbon monoxide poisoning may be an important cause to reduce NO level in blood. This study provides the basis for low NO concentration inhalation in treatments of acute carbon monoxide poisoning.

Acute Disease ; Carbon Dioxide ; blood ; Carbon Monoxide Poisoning ; blood ; Humans ; Nitric Oxide ; blood ; Oxygen ; blood

This experimental study was performed on 5 rabbits to ascertain if oxygenated Ringer's lactate Could be used in place of fluorocarbons through peritoneal administration. Oxygen was bubbled through solutions of Ringer's lactate at two different rates and the oxygen tension of each solution was determined. The solution used in vivo had oxygen delivered at a rate of 5 L/min; the mean PO2 and pH were 575.5 mmHg and 6.34 respectively, while the rate of oxygenation of the in vitro solution was 3 L/min. with a mean PO2 and pH of 416.6 mmHg and 6.08. After peritoneal administration of the oxygenated solution the PaO2 values were significantly increased from the control value. Other parameters such as pH, PaCO2, HCO3, BE, SO2 (oxygen saturation), Na and K were not shown to be statistically significant. Some degree of oxygenation could be obtained by the introduction of oxygenated Ringer's solution. This result suggested that this solution can be used for oxygenation via the transperitoneal administration, and that this method of oxygenation may possibly be used to treat some forms of respiratory failure.
Animal ; Infusions, Parenteral ; Isotonic Solutions/administration & dosage* ; Oxygen/administration & dosage* ; Oxygen/blood ; Rabbits

To observe the relationship between oxygen consumption and body temperature during cardiopulmonary bypass, the authors checked nasopharyngeal and rectal temperature, hemoglobin, and arterial and venous blood gas analysis. At the time when nasopharyngeal and rectal temperatures were equal, it was shown that oxygen consumption had a good relationship (r=0.78) with body temperature. From this data it was revealed that oxygen consumption decreased with decreasing temperature at the rate of about 0.16 ml/kg/min/C.
Blood Gas Analysis ; Body Temperature* ; Cardiopulmonary Bypass ; Extracorporeal Circulation* ; Oxygen Consumption* ; Oxygen*

Oxygen reserve index (ORI) is a novel dimensionless index used for noninvasive, real-time, and continuous monitoring of oxygenation, and ORI value ranges from 0 to 1, which reflects the range of 100-200 mmHg for arterial partial pressure of oxygen. ORI combined with pulse oximetry may help to accurately adjust the concentration of inspired oxygen and prevent hyperoxemia and hypoxemia. ORI is suitable for various clinical situations, and the medical staff should master this novel parameter and use it properly to assess the oxygenation of patients. In addition, several limitations of ORI should be noticed during clinical application.
Humans ; Oxygen ; Blood Gas Analysis ; Oxygen Inhalation Therapy ; Oximetry ; Hypoxia/therapy*

OBJECTIVETo explore the mechanism of Tuina for treatment of chronic fatigue syndrome.

METHODSA total of 90 patients were randomly divided into a Tuina group, a Taijiquan (take exercise) group and a Fluoxetine group, 30 cases in each group. They were treated with Tuina, Taijiquan and Fluoxetine, respectively. After a month, the therapeutic effects and the changes of malondialdehyde (MDA) content and the activity of serum superoxide dismutases (SOD) and serum glutathione peroxidase (GSH-Px) were ohserved.

RESULTSThe total effective rate of 93.3% (28/30) in the Tuina group was better than 80.0% (24/30) in the Taijiquan group and 73.3% (22/30) in the Fluoxetine group (both P < 0.05). After treatment, MDA contents in the three groups were all decreased (P < 0.01, P < 0.05), and the activity of SOD. GSH-Px in both the Tuina group and the Fluoxetine group were increased (P < 0.01, P < 0.05), and especially in the Tuina group with a significant difference as compared with the other two groups (P < 0.05, P < 0.01).

CONCLUSIONThe therapeutic effect of the Tuina group is superior to that of the Taijiquan group and the Fluoxetine group. Tuina can regulate oxygen free radicals metabolism and clean superfluous oxygen free radicals to alleviate fatigue, which may be one of the mechanisms of Tuina in treating chronic fatigue syndrome.

Adult ; Fatigue Syndrome, Chronic ; blood ; enzymology ; therapy ; Female ; Glutathione Peroxidase ; blood ; Humans ; Male ; Malondialdehyde ; blood ; Massage ; Middle Aged ; Oxygen ; Reactive Oxygen Species ; blood ; Superoxide Dismutase ; blood