Humans ; Hypersensitivity/complications* ; Otitis Media/complications* ; Otitis Media with Effusion/etiology*

Otitis media with effusion (OME) was first described by Austrian otologist POLITZERZAI in 1867. The main feature is ear effusion and conductive hearing loss. However the etiology and pathogenesis of OME has not been clear up to now. It is thought that OME can be induced by upper respiratory infection,also can arise after radiotherapy of head and neck cancer. Presently the dysfunction of eustachian tube,infection of middle ear and allergic reaction are considered to be the major causes of OME. In recent years, more and more researches have concerned in immune response and otitis media with effusion.
Animals ; Humans ; Hypersensitivity ; Otitis Media with Effusion ; etiology ; immunology

Case-Control Studies ; Child ; Female ; Humans ; Male ; Otitis Media with Effusion ; etiology ; Risk Factors

OBJECTIVE: The aim of this study is to investigate the incidence and natural history of secretory otitis media(SOM) and hearing loss in newborns and infants with cleft palate, consequently, define its audiological criteria and to predict SOM early. METHOD: Seventy-three newborns and infants with a cleft palate (146 ears) were monthly estimated by tympanogram, static compliance, acoustic stapedius reflex and auditory brainstem response (ABR) under natural sleep within one year of age. RESULT: Au the infants with cleft palate had the suspected SOM in the first 6 months of life. Among children with cleft palate, the suspected SOM were most prevalent in the 3-month-age. 78. 8% infants with cleft palate had the confirmed SOM in the first 12 months of life. SOM were most prevalent in the 6-month-age. The SOM prodromal period was averagely 3. 8 months from suspected SOM to confirmed SOM. 56. 2% infants with cleft palate had a conductive hearing loss in the first 12 months of life. The conduction hearing thresholds of ABR (2-4 Hz) were averagely 48. 6 dBnHL. CONCLUSION The highest incidence of SOM and hearing loss in children with cleft palate appear in infants in the first 1 year of life. The process of SOM and hearing loss onset is progressive process. The infants with cleft palate should be estimated by ABR and acoustic immittance audiometry in each period of 2 or 3 months after birth.
Cleft Palate ; complications ; Female ; Hearing Loss ; epidemiology ; etiology ; Humans ; Incidence ; Infant ; Infant, Newborn ; Male ; Otitis Media with Effusion ; epidemiology ; etiology

Adult ; Female ; Humans ; Meningeal Neoplasms ; complications ; diagnosis ; Meningioma ; complications ; diagnosis ; Otitis Media with Effusion ; diagnosis ; etiology ; Skull Base Neoplasms ; complications ; diagnosis

OBJECTIVETo identify the risk factors for otitis media with effusion (OME) in some kindergarten children in Wuhan City of China and analyze the results with reference to the review of the literature.

METHODSThe study subjects were 3 to 6 years old children drawn from a school screening program for OME in Wuhan. All subjects were assessed with routine otorhinolaryngologic examination, otoscopic examination and tympanometry. During the test, parents were interviewed to provide information with regard to the children's birth history, neonatal history, feeding history, family smoke history, otological history, rhinorrhea, sneeze, nasal obstruction, snoring, tonsillitis episodes history, et al. These data formed the basis in the estimation of potential risk factors for OME.

RESULTSIn the univariate analysis of 144 cases and 288 controls, significantly elevated odds ratios (OR) for OME were detected on the symptoms of nasal obstruction (OR = 2.60, P = 0.002), rhinorrhoea (OR = 1.442, P = 0.003), high hard palate (OR = 4.411, P < 0.0001), and previous history of acute otitis media (OR = 1.77, P = 0.025). However, four factors were found to be significant in the multivariate logistic regression model, including feeding history (OR = 0.746, P = 0.047), nasal obstruction (OR = 2.56, P = 0.003) and previous acute otitis media episodes (OR = 1.735, P = 0.032).

CONCLUSIONSPrevious acute otitis media episodes and nasal obstruction were risk factors, which was accordant with literature. In addition, breastfeeding was a protective factor for OME, but acute tonsillitis was not a factor for OME. A child who had previous acute otitis media episode and often had nasal obstruction is suggested to have otorhinolaryngologic regulatory examination.

Child ; Child, Preschool ; China ; epidemiology ; Female ; Humans ; Male ; Otitis Media with Effusion ; epidemiology ; etiology ; Risk Factors ; Surveys and Questionnaires

OBJECTIVE: The analyze the relationship between secretory otitis media (SOM) and injury of tensor veli palatini (TVP) muscle injury after radiotherapy, then to explore the pathogenesis of SOM in patients with nasopharyngeal carcinoma (NPC) after radiotherapy. METHOD: The cross section area (CSA) of TVP and medial pterygoid (MP) muscle were measured in MRI of 32 patients with NPC before and after radiotherapy, meanwhile the incidence of SOM were surveyed after radiotherapy, then to analyze the relationship between the change of TVP and the incidence of SOM after radiotherapy. RESULT: Of 48 ears without SOM before radiotherapy, 27 ears developed post-irradiation SOM, including 24 ears with TVP atrophy and 3 ears without TVP atrophy, and 21 ears had no post-irradiation SOM, including 8 ears with TVP atrophy and 13 ears without TVP atrophy. chi2 test showed significant difference (P < 0.01). It indicated that post-irradiation SOM have correlation with TVP atrophy. The more possibility of TVP atrophy occurred after long time radiotherapy. CONCLUSION The atrophy of TVP in patients with NPC usually occurs 6 months after radiotherapy, and this may result in the post-irradiation SOM. The pathogenesis of post-irradiation SOM need further study functionally.
Adult ; Aged ; Female ; Humans ; Male ; Middle Aged ; Nasopharyngeal Neoplasms ; radiotherapy ; Otitis Media with Effusion ; etiology ; Palatal Muscles ; pathology ; Palate, Soft ; pathology

OBJECTIVE: To propose the concept of rhinogenic otitis media and explore its pathomechanism through analyzing the diagnosis and treatment on secretory otitis media caused by unhealthy nasal cavity structure. METHOD: Conservative treatment and correlative operation under nasoscope were undertaken in 176 otitis media patients with unhealthy nasal cavity structure. RESULT: Of 176 cases, 156 cases recovered completely (88.64%), 18 cases got effective treatment (10.23%), and 2 cases got ineffective treatment (1.14%). CONCLUSION One important cause of the secretory otitis media is unhealthy nasal cavity structure, so correcting the unhealthy nasal cavity structure is the main ways to treat rhinogenic otitis media.
Adolescent ; Adult ; Aged ; Female ; Humans ; Male ; Middle Aged ; Nasal Cavity ; pathology ; Otitis Media with Effusion ; diagnosis ; etiology ; surgery ; Young Adult

In this paper, patients with the left ear hearing loss, aural fullness. CT: the left wing palatine nest sites. MRI: on the left wing palatine timid benign lesions; Electric listening: conductive deafness. Acoustic immittance: B type curve. Clinical diagnosis: the left wing palatine fossa cyst, left ear secretory otitis media.
Acoustic Impedance Tests ; Auditory Perception ; Cysts ; diagnosis ; Deafness ; diagnosis ; etiology ; Hearing Loss, Conductive ; etiology ; Humans ; Magnetic Resonance Imaging ; Otitis Media with Effusion ; diagnosis

Objective: To analyze the incidence and risk factors of otologic disorders in patients with Turner syndrome (TS), so as to provide management strategies for ear health. Methods: This study is a prospective study based on questionnaires and a cross-sectional study. The TS patients who visited our hospital from 2010 January to 2021 March were included (A total of 71 patients with TS were included in this study. the age of TS diagnosed was 3- to 11-year-old, age of visiting ENT department was 4- to 27-year-old) and the incidence of otologic diseases in different age groups was investigated by questionnaires. The cross-sectional study included ear morphology and auditory function assessment, and further analysis of the risk factors that related to ear disease. Prism was used for data analysis. Results: The investigation found that the incidence of acute otitis media in patients aged 3-6 and 7-12 years was higher than that of patients over 12 years old, which was 33.8%(24/71), 42.9%(30/70)and 23.5%(8/34), respectively; 21.1% (15/71) of patients were recurrent acute otitis media in patients aged 3-6 years, and about 46.6% (7/15)of them persisted beyond 6-year. The prevalence of otitis media with effusion in the three groups was 32.4%(23/71), 34.3%(24/70)and 38.2%(13/34), respectively; the recurrence rate of tympanocentesis was 100%(7/7), 42.9%(3/7)and 50.0%(1/2), which was significantly higher than that of grommet insertion. For age groups of 3-6 and 7-12 years, the prevalence of acute otitis media and secretory otitis media was lower in the X chromosome structure abnormal patients; while for patients older than 12 years, otitis media with effusion was the highest prevalence in Y-chromosome-containing karyotypes. In addition, the prevalence of acute otitis media and otitis media with effusion in patients with other system diseases were increased significantly. A cross-sectional study found that 7.0% (5/71)of the lower auricular, 4.2% (3/71)of the external auditory canal narrow, and 38.0% (27/71)of the tympanic membrane abnormality. 35.2%(25/71) had abnormal hearing, including 17 cases of conductive deafness, 6 cases of sensorineural hearing loss, and 2 cases of mixed deafness. The rest of the patients had normal hearing, but 6 of them had abnormalities in otoacoustic emission. Eustachian tube function assessment found that the eustachian tube dysfunction accounted for 38%(27/71). Hearing loss and abnormal Eustachian tube function were not significantly related to karyotype(Chi-square 2.83 and 2.84,P value 0.418 and 0.417), but significantly related to other system diseases(Chi-square 13.43 and 7.53,P value<0.001). Conclusions: The incidence of TS-related otitis media and auditory dysfunction is significantly higher than that of the general population. It not only occurs in preschool girls, but also persists or develops after school age. Accompanied by other system diseases are risk factors for ear diseases. Clinicians should raise their awareness of TS-related ear diseases and incorporate ear health monitoring into routine diagnosis and treatment.
Adolescent ; Adult ; Child ; Child, Preschool ; Cross-Sectional Studies ; Deafness/etiology* ; Female ; Humans ; Middle Ear Ventilation/adverse effects* ; Otitis Media/complications* ; Otitis Media with Effusion/complications* ; Prospective Studies ; Turner Syndrome/therapy* ; Young Adult