1. STUDY WORK FOR STRUCTURE OF THE WAREHOUSE OF THE PHARMACEUTICAL WHOLESALE CENTER AND THEIR ACTIVITIES.
Otgonbileg B ; Uranchimeg M ; Khurelbaatar L
Mongolian Pharmacy and Pharmacology 2013;2(1):51-
Foundation of the research: The issues of safety and qualified medicine industrial, supplyment and maintenance is the counterpart of national security policy about any nations. Mongolia has been importing over 80% of domestic demand of medicine.New drugs have accessed into marked and medicine distributors or suppliers, pharmacies have established as many, thus its generating the needs to improve the legal environ for to reach the new level of quality control, medicine suppliers structure and activities, then also to verify the safety of imported or local medicine.May having formulize the requirements of medicine warehouse, remodify the standard of Medicine Supply Organization can be the first step to solve the problems which Medicine Supply Organization has been facing.The purpose and goals of research work: Submitting following goals in the frame of the purpose to analyze the condition of the Medicine Supply Organization’s warehouse, study the foreign country’s GSP and utilize the standard instruction of medicine warehouse by determine the method of access it into Mongolian bigger Medicine Supply Organization. Thereof:1.Make analysis and assessment on the current condition of Mongolian Medicine warehouse.2.Conduct the research work based on the guidance of World Health Organization, European UnioN warehouse standard and other foreign country’s warehouse standard.3.To utilize the medicine warehouse standard guidance for Mongolia.The methodology: Have selected and incorporated with 5 top company which are operating as medicine importer based on value of imported products for last 3 years and 3 The pharmaceutical wholesale center which had lesser scope and totally means 8 companies.We used following methods such as observation study, open review survey, schematic and comparative study, method of interview and review and documentation method.THE RESULT OF RESEARCH WORK: Even though,those research involved organizations have met with the requirements of MNS 5530:2009 Medicine Supply Organization Standard by 71%, and risk assessment was in low risk category as by 20% under the State Specialized Inspection Agency, but accordingly with the World Health Organization’s formulized GSP’s guidance, it haven’t freezing and cooling chain storage condition of medical product storage. Research involved The pharmaceutical wholesale center provides activity supervision indication of GSP’s guidance by 30%, required parts of warehouse structure by 43% and supportive parts of warehouse operation by 22%.CONCLUSION:1. However, that research involved the pharmaceutical wholesale center have reached 71% of the requirement of MNS 5530:2009 standard of Medicine Supply Organization and fitted in low risk category as 20% according with the risk assessment of State Specialized Inspection Agency, but was lower by 68% than building construction standard and activities according with the GSP’s guidance.2. Have determine the solutions for resolvable factors which are unreached the requirements of GSP based on the study of World Health Organization, European Union GSP requirements, Kazakhstan, Bulgaria, Germany and Russian by linked it with the condition of research involved organizations.Utilized the Mongolian medicine warehouse standard guidance.
2. EPIDEMIOLOGIC STUDY OF ORAL AND MAXILLOFACIAL SURGERY PATIENTS IN MONGOLIA
Davaadorj P ; Otgonbileg E ; Bold M ; Odkhuu J ; Purevdorj G ; Denis S ; Ayanga G ; Khuderchuluun CH ; Batbayar B ; Baasanjav N ; Oyunaa CH ; Budmaa S ; Khentii L
Innovation 2015;9(Dentistry):16-20
The purpose of this study was to analyze the epidemiology of oral and maxillofacial surgery patients in Mongolia and advocate guidelines and programs to promote optimal oral health care. A fact-finding epidemiologic study on the patients who visited at Departments of Oral and Maxillofacial Surgery, at National Hospitals at Ulaanbaatar city and Province and other Central hospitals of Mongolian, from Jan to Dec, 2013.Total 12957 patients treated at inpatients care center at the above mentioned national hospitals. From Ulaanbaatar city were 4284 (36%) and from province were 7673 (64%). Patients from province were treated at FCH 69%, NTORC 6.4%, NCC 11.3%, NCMCH 27% and CMAFH 1.8%. Zero to 16 years, 17 to 36 years, 37 to 56 years and 57 or more years old patients were3072 (27.1%), 4224 (34.2%), 3218 (26.9%) and 1412 (11.8%), respectively. Males and females were 6841 (53%), 6090 (47%). Cases of the inpatients were as follows: infectious disease 5971 (49.88), benign tumor 1039 (8.01%), trauma & injury 1799 (15%), salivary gland disease 2.41%, TMJ disease 2.8%, neuralgia and muscle pain 0.8% and others. 5 provinces have no Oral and Maxillofacial Surgeon and patients were referred to other central hospitals or to the Ulaanbaatar city. This study gives a topic of conversation about undergraduate dental education, continuing education and enough specialists in the region.
3.The study of the intestinal microbiota among Mongolian Adults, it related some factors
Saruuljavkhlan B ; Battogtokh Ch ; Enkh-Amar A ; Otgonjargal B ; Otgonbileg J ; Anuujin G ; Gerelmaa E ; Bira N
Mongolian Medical Sciences 2019;188(2):3-11
Background:
The intestinal microbiota of Mongolians and its composition is of great interest of researchers, a few studies
have did in this fields. Maybe Mongolian encompass a uniquely wide range of environmental conditions, ethno
geographical cohorts and traditional nomadic lifestyles.
Goal:
We aimed to determine the amount of gut microbiota, including Lactobacillus and Bifidobacterium in the fecal
samples of relative healthy Mongolian adults residing in various regions of Mongolia by conventional culture
method and PCR.
Material and Methods:
The study was performed population based cross sectional study in healthy volunteers. In this study, 256
relative healthy Mongolian adults with no history of gastrointestinal associated diseases were enrolled
between July 2018 and April 2019. Each participants was asked to complete a questionnaire containing 164
questions about demographics, physical activity, dietary habits. Fecal samples were collected for Lactobacillus
and Bifidobacterium analysis using culture method and determination of genus of Bifidobacterium sрp and
Lactobacillus spp by PCR.
ResultsParticipants had a mean age of 38.9±12.8 years. The mean values of Lactobacillus
by culture method were 5.9±1.28 and 6.24±0.94 log10 CFU/ml (4.67х106
, 4.66х106 CFU/ml), respectively. The
abundance of Lactobacillus had a positive correlation with grams for fiber and amount of bifidobacterium ((r=
0.495, р<0.001, r=0.288, p<0.05), respectively). Significant difference were observed between groups of milk
frequency per day for amounts of lactobacillus. In adult intestinal tracts, B.Bifidum was the most common taxon
31 (29%) followed by B. angulatum 14 (13.1%), B. adolescentis 10 (9.3%), B. catenulatum group 10 (9.3%), B.
longum 9 (8.4%). B. lactis, B. breve, B. dentium and B. gallicum were subdominant species.
Conclusion:
The mean amount of Bifidobacterium and Lactobacillus of all participants were 6.24±0.94 and 5.9±1.28 log10
CFU/ml (4.66*106
, 4.67*106
CFU/ml) respectively. The Lactobacillus abundance of healthy adults was higher in
region of Khangai, East and West of Mongolian than other regions. The composition of lactobacillus altered with
ageing. Significant correlations were found between fiber, fats, potato and amount of Lactobacillus.
Keywords: Bifidobacterium, Colony forming unit, Gut microbiota, Lactobacillus