1.Paget's disease of bone: one case report.
Woon Sik CHOY ; Chang Hyun BAEK ; Dong Hoo KOH
The Journal of the Korean Orthopaedic Association 1991;26(3):970-974
No abstract available.
Osteitis Deformans*
2.A Case of Paget's Disease of Bone on Skull.
Soo Jin CHUNG ; Yong Jin KWON ; Min Chan PARK
The Journal of the Korean Rheumatism Association 2009;16(4):344-346
No abstract available.
Osteitis Deformans
;
Skull
4.Paget's Disease of Bone with Pathologic Fracture of the Femur: a Case Report
Kwang Hoe KIM ; Jae Lim CHO ; Tae Seung KIM ; Joon Sik KIM
The Journal of the Korean Orthopaedic Association 1989;24(1):316-321
Paget's disease is one of the chronic disorders of skeletal system which is frequently accompained with pathologic fractures. This disease is extremely rare in Korea and only three cases have been reported in the Journal of Korean Orthopaedic Associstion. And all these cases were not associated with pathologic fracture. We experienced a case of Paget's disease with pathologic fracture of the femur which is typical in radiologic, laboratory and histopathologic findings.
Femur
;
Fractures, Spontaneous
;
Korea
;
Osteitis Deformans
5.A case of monostotic paget's disease
Cheol Min PARK ; Jung Hyuk KIM ; In Ho CHA ; Chang Hong LEE ; Seok Hyun LEE ; Kap No LEE
Journal of the Korean Radiological Society 1985;21(2):323-327
Paget's disease of bone (osteitis deformans), a chronic osseous disease of unknown etiology, is extremely rarein Asia although well known in western countries. This disease is characterized by the simultaneous absorption ofbone and the new bone formation of abnormal character affecting middle and later age groups. The authorsexperienced a case of monostotic Paget's disease involving left pelvic bone in 56-years old female. To ourknowledge, this is the first cas report of monostotic Paget's in Korea.
Absorption
;
Asia
;
Female
;
Humans
;
Korea
;
Osteitis Deformans
;
Osteogenesis
;
Pelvic Bones
6.Intravenous Zoledronate for a Patient with Paget's Disease.
Journal of Bone Metabolism 2014;21(3):223-226
Paget's disease (PD) of bone is characterized by increase of bone resorption by atypical osteoclasts, followed by rapid new bone formation resulting in a disorganized mosaic bone. Although the pathophysiology is not fully understood, bisphosphonate, which is a potent anti-resorptive agent for treatment of osteoporosis, have been the most effective agents available for the treatment of PD. We report a case of PD of bone in a 49-year-old woman patient, who was treated with intravenous zoledronate.
Bone Density Conservation Agents
;
Bone Resorption
;
Diphosphonates
;
Female
;
Humans
;
Middle Aged
;
Osteitis Deformans
;
Osteoclasts
;
Osteogenesis
;
Osteoporosis
7.Hypercalcemia Refractory to Pamidronate Associated with Metastatic Calcifications in Multiple Organs.
Gi Bum BAE ; Jung Su EUN ; Na Ri KIM ; Churl Hyun IM ; Eon Jeong NAM ; Young Mo KANG
Korean Journal of Medicine 2013;85(5):545-550
Paget's disease of bone (PDB) is a disorder featuring high-level bone turnover associated with the presence of disorganized and immature bone tissue with excessive levels of fibrosis. The risk of deformity is very high. The etiology of PDB is not well understood, but includes both genetic and environmental factors among which is bone trauma. Hypercalcemia can occur as a complication of PDB in patients who are immobilized and dehydrated. However, to date, no case of severe hypercalcemia with metastatic calcifications in multiple organs has been reported in any PDB patient. The drugs of choice for treatment of PDB are bisphosphonates. These drugs effectively suppress bone turnover. Patients with extensive PDB may require higher doses of bisphosphonates, and acquired resistance to a particular bisphosphonate may be overcome by use an alternative drug. Here, we report a case of suspicion of PDB. The patient presented with hypercalcemia and metastatic calcifications and his condition improved dramatically after treatment with zoledronic acid.
Bone and Bones
;
Congenital Abnormalities
;
Diphosphonates
;
Fibrosis
;
Humans
;
Hypercalcemia*
;
Imidazoles
;
Osteitis Deformans
;
Wounds and Injuries
8.Hypercalcemia Refractory to Pamidronate Associated with Metastatic Calcifications in Multiple Organs.
Gi Bum BAE ; Jung Su EUN ; Na Ri KIM ; Churl Hyun IM ; Eon Jeong NAM ; Young Mo KANG
Korean Journal of Medicine 2013;85(5):545-550
Paget's disease of bone (PDB) is a disorder featuring high-level bone turnover associated with the presence of disorganized and immature bone tissue with excessive levels of fibrosis. The risk of deformity is very high. The etiology of PDB is not well understood, but includes both genetic and environmental factors among which is bone trauma. Hypercalcemia can occur as a complication of PDB in patients who are immobilized and dehydrated. However, to date, no case of severe hypercalcemia with metastatic calcifications in multiple organs has been reported in any PDB patient. The drugs of choice for treatment of PDB are bisphosphonates. These drugs effectively suppress bone turnover. Patients with extensive PDB may require higher doses of bisphosphonates, and acquired resistance to a particular bisphosphonate may be overcome by use an alternative drug. Here, we report a case of suspicion of PDB. The patient presented with hypercalcemia and metastatic calcifications and his condition improved dramatically after treatment with zoledronic acid.
Bone and Bones
;
Congenital Abnormalities
;
Diphosphonates
;
Fibrosis
;
Humans
;
Hypercalcemia*
;
Imidazoles
;
Osteitis Deformans
;
Wounds and Injuries
9.Report of a case with Paget disease with bilateral progressive hearing loss as the first symptom.
Li MENG ; Hui-Fang ZHOU ; Jian-Ling WANG
Chinese Journal of Otorhinolaryngology Head and Neck Surgery 2009;44(7):602-603
Aged
;
Female
;
Hearing Loss, Bilateral
;
diagnosis
;
etiology
;
Humans
;
Osteitis Deformans
;
complications
;
diagnosis