1.Paget's disease of bone: one case report.
Woon Sik CHOY ; Chang Hyun BAEK ; Dong Hoo KOH
The Journal of the Korean Orthopaedic Association 1991;26(3):970-974
No abstract available.
Osteitis Deformans*
2.A Case of Paget's Disease of Bone on Skull.
Soo Jin CHUNG ; Yong Jin KWON ; Min Chan PARK
The Journal of the Korean Rheumatism Association 2009;16(4):344-346
No abstract available.
Osteitis Deformans
;
Skull
3.Paget's Disease of Bone with Pathologic Fracture of the Femur: a Case Report
Kwang Hoe KIM ; Jae Lim CHO ; Tae Seung KIM ; Joon Sik KIM
The Journal of the Korean Orthopaedic Association 1989;24(1):316-321
Paget's disease is one of the chronic disorders of skeletal system which is frequently accompained with pathologic fractures. This disease is extremely rare in Korea and only three cases have been reported in the Journal of Korean Orthopaedic Associstion. And all these cases were not associated with pathologic fracture. We experienced a case of Paget's disease with pathologic fracture of the femur which is typical in radiologic, laboratory and histopathologic findings.
Femur
;
Fractures, Spontaneous
;
Korea
;
Osteitis Deformans
5.A case of monostotic paget's disease
Cheol Min PARK ; Jung Hyuk KIM ; In Ho CHA ; Chang Hong LEE ; Seok Hyun LEE ; Kap No LEE
Journal of the Korean Radiological Society 1985;21(2):323-327
Paget's disease of bone (osteitis deformans), a chronic osseous disease of unknown etiology, is extremely rarein Asia although well known in western countries. This disease is characterized by the simultaneous absorption ofbone and the new bone formation of abnormal character affecting middle and later age groups. The authorsexperienced a case of monostotic Paget's disease involving left pelvic bone in 56-years old female. To ourknowledge, this is the first cas report of monostotic Paget's in Korea.
Absorption
;
Asia
;
Female
;
Humans
;
Korea
;
Osteitis Deformans
;
Osteogenesis
;
Pelvic Bones
6.Intravenous Zoledronate for a Patient with Paget's Disease.
Journal of Bone Metabolism 2014;21(3):223-226
Paget's disease (PD) of bone is characterized by increase of bone resorption by atypical osteoclasts, followed by rapid new bone formation resulting in a disorganized mosaic bone. Although the pathophysiology is not fully understood, bisphosphonate, which is a potent anti-resorptive agent for treatment of osteoporosis, have been the most effective agents available for the treatment of PD. We report a case of PD of bone in a 49-year-old woman patient, who was treated with intravenous zoledronate.
Bone Density Conservation Agents
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Bone Resorption
;
Diphosphonates
;
Female
;
Humans
;
Middle Aged
;
Osteitis Deformans
;
Osteoclasts
;
Osteogenesis
;
Osteoporosis
7.Hypercalcemia Refractory to Pamidronate Associated with Metastatic Calcifications in Multiple Organs.
Gi Bum BAE ; Jung Su EUN ; Na Ri KIM ; Churl Hyun IM ; Eon Jeong NAM ; Young Mo KANG
Korean Journal of Medicine 2013;85(5):545-550
Paget's disease of bone (PDB) is a disorder featuring high-level bone turnover associated with the presence of disorganized and immature bone tissue with excessive levels of fibrosis. The risk of deformity is very high. The etiology of PDB is not well understood, but includes both genetic and environmental factors among which is bone trauma. Hypercalcemia can occur as a complication of PDB in patients who are immobilized and dehydrated. However, to date, no case of severe hypercalcemia with metastatic calcifications in multiple organs has been reported in any PDB patient. The drugs of choice for treatment of PDB are bisphosphonates. These drugs effectively suppress bone turnover. Patients with extensive PDB may require higher doses of bisphosphonates, and acquired resistance to a particular bisphosphonate may be overcome by use an alternative drug. Here, we report a case of suspicion of PDB. The patient presented with hypercalcemia and metastatic calcifications and his condition improved dramatically after treatment with zoledronic acid.
Bone and Bones
;
Congenital Abnormalities
;
Diphosphonates
;
Fibrosis
;
Humans
;
Hypercalcemia*
;
Imidazoles
;
Osteitis Deformans
;
Wounds and Injuries
8.Hypercalcemia Refractory to Pamidronate Associated with Metastatic Calcifications in Multiple Organs.
Gi Bum BAE ; Jung Su EUN ; Na Ri KIM ; Churl Hyun IM ; Eon Jeong NAM ; Young Mo KANG
Korean Journal of Medicine 2013;85(5):545-550
Paget's disease of bone (PDB) is a disorder featuring high-level bone turnover associated with the presence of disorganized and immature bone tissue with excessive levels of fibrosis. The risk of deformity is very high. The etiology of PDB is not well understood, but includes both genetic and environmental factors among which is bone trauma. Hypercalcemia can occur as a complication of PDB in patients who are immobilized and dehydrated. However, to date, no case of severe hypercalcemia with metastatic calcifications in multiple organs has been reported in any PDB patient. The drugs of choice for treatment of PDB are bisphosphonates. These drugs effectively suppress bone turnover. Patients with extensive PDB may require higher doses of bisphosphonates, and acquired resistance to a particular bisphosphonate may be overcome by use an alternative drug. Here, we report a case of suspicion of PDB. The patient presented with hypercalcemia and metastatic calcifications and his condition improved dramatically after treatment with zoledronic acid.
Bone and Bones
;
Congenital Abnormalities
;
Diphosphonates
;
Fibrosis
;
Humans
;
Hypercalcemia*
;
Imidazoles
;
Osteitis Deformans
;
Wounds and Injuries
9.A Case of Giant Cell Tumor of Bilateral Maxilla with Paget's Disease.
Yu Sung WON ; Aa Ron LEE ; Jin Hee CHO ; He Ro YOON
Korean Journal of Otolaryngology - Head and Neck Surgery 1998;41(8):1087-1090
Giant cell tumors acount for 4% of all bone tumors and usually occur in the epiphyses of long bones and rarely involve the head and neck region, representing about 9% of them. The incidence of giant cell tumor arising in Paget's disease, which is characterized by a bizarre and greatly exaggerated skeletal turnover, is probably less than 0.2%. We experienced a case of giant cell tumor in the bilateral maxilla with Paget's disease of bone, which was treated by excision and curettage of the tumor mass via endoscopic approach.
Curettage
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Epiphyses
;
Giant Cell Tumors*
;
Giant Cells*
;
Head
;
Incidence
;
Maxilla*
;
Neck
;
Osteitis Deformans
10.A Case of Intractable Bisphosphonate-Related Osteonecrosis of the Jaw Treated with Teriparatide
Sujin LEE ; Ji Hye HUH ; Won Jin KIM ; Kyoung Min KIM ; In Ho CHA ; Yumie RHEE
Journal of Korean Society of Osteoporosis 2012;10(2):76-81
Bisphosphonates are the most widely used medications for treating high bone turnover osteoporosis, Paget's disease of bone, multiple myeloma and metastatic carcinomas, etc. However, a destructive complication of bisphosphonate-related osteonecrosis of the jaw (BRONJ) can occur. The treatments of BRONJ are challenging and the currently recommended managements for BRONJ are still controversial. Our case demonstrated that teriparatide can be a treatment of choice for intractable BRONJ, which had not been cured for 2 years even with the proper surgical treatment and withdrawal of bisphosphonates.
Bisphosphonate-Associated Osteonecrosis of the Jaw
;
Diphosphonates
;
Multiple Myeloma
;
Osteitis Deformans
;
Osteoporosis
;
Teriparatide