No abstract available.
Ossicular Prosthesis*

The ossicular replacement prosthesis should have good biocompatibility, stability, easy to install, and excellent sound transmission capacity. In this study, the characteristics of ideal materials for the ossicular replacement prosthesis were analyzed by searching the types of materials used in clinical practice and comparing the advantages and disadvantages of various materials and structures. At the same time, in combination with the current evaluation requirements and evaluation experience, the focus of the performance research project of ossicular replacement prosthesis in the process of registration is discussed to clarify the performance evaluation requirements of these products, so as to provide reference for the future work of manufacturers and regulators. The performance evaluation of ossicular replacement prosthesis focuses on its mechanical properties, fixation stability, sound transmission characteristics, biological characteristics, and magnetic resonance compatibility.
Ossicular Prosthesis ; Ossicular Replacement ; Sound ; Prosthesis Design ; Treatment Outcome

Ear Ossicles ; Humans ; Ossicular Prosthesis ; Ossicular Replacement ; Recovery of Function

BACKGROUND AND OBJECTIVE: During the last decade, the surgical use of alloplasts has become more and more widespread among otologists. But extrusion has been the general problem associated in using alloplasts. This study analyzes the change of' surface and microcomponent of the extruded Polycel prosthesis following a long-term middle ear implantation. MATERIALS AND METHODS: Nine extruded Polycel prosthesis were investigated using scanning electronmicroscopy (SEM) and energy dispersive spectrometer (EDS). RESULTS: They all showed a severe resorption of fibrous encapsulation and partial resorption of the shaft which faced stapes and footplate. The carbon component decreased and nitrogen and oxide increased more than the original Polycel due to microdegradation. CONCLUSION: Consistent microdegradation and resorption may be one of the factors causing extrusion of Polycel.
Carbon ; Nitrogen ; Ossicular Prosthesis* ; Prostheses and Implants ; Stapes

BACKGROUND AND OBJECTIVES: Multiple techniques of ossicular replacement have been advocated for hearing gain in the setting of chronic otitis media. The purpose of this study is to investigate hearing gain in the middle ear surgery according to the surgical technique and the materials. MATERIALS AND METHOD: Ninety-nine cases with ossicular replacement with mastoidectomy in the Konkuk University Hospital from 1995 to 2001 were reviewed retrospectively. Postoperative hearing gains were compared with the two methods of mastoidectomy and the two materials of ossicular replacement separately. RESULTS: A successful hearing gain was defined as a postoperative air-bone gap less than 30dB. According to this criterion, 47% of intact canal wall mastoidectomy cases and 43% of open cavity mastoidectomy cases were successful. Thirty-one percent of ossicular replacement case using cartilage-perichondrium and 62% using hydroxyapatite-PORP were successful. The extrusion rate was zero % in ossicular replacement using cartilage-perichondrium, and 57% in ossicular replacement using PORP. CONCLUSION: There was a significant differences in hearing gain and extrusion rate by using two different materials for ossicular replacement such as cartilage and hydroxyapatite-PORP (p<0.05). There was no statistically significant differences in hearing gain between the two methods of mastoidectomy (p>0.05).
Cartilage ; Ear, Middle ; Hearing* ; Incus* ; Malleus* ; Ossicular Prosthesis ; Ossicular Replacement ; Otitis Media ; Retrospective Studies

BACKGROUD AND OBJECTIVES: Incus erosion with intact stapes head was most common ossicular impairment in chronic otitis media. Here, we aimed to investigate hearing and clinical results of the ossiculoplasties when the stapes head was intact. SUBJECTS AND METHOD: We analyzed 281 patients of ossiculoplasties over stapes head performed from 1990 to 2005. Patients were divided into 3 groups: Si group (n=121) included patients with interposition of prosthesis between malleus and stapes; Sc-PORP group (n=99) included patients with columellarization between tympanic membrane and stapes head with PORP; Sc-SC group (n=61) included patients with columellarization with the autologous materials between tympanic membrane and stapes head. Hearing improvement and extrusion rates of three groups were analyzed. RESULTS: At 6 months after the surgery, the postoperative air-bone gap (ABG) level within 20 dB was 45%, 44%, 25% in Si, Sc-PORP, Sc-Sc, respectively. The closure of ABG was statistically better in Si and Sc-PORP compared with Sc-SC. In canal wall-up mastoidectomy, Sc-PORP showed better hearing results than Si, while Si was better than Sc-PORP in canal wall-down mastoidectomy. At 36 months after the surgery, extrusion-free survival according to the type of ossiculoplasty were 100%, 89.6%, 100% in Si, Sc-PORP, Sc-SC, respectively. CONCLUSION: Si and Sc-PORP provide good hearing results. However, Si has lower extrusion rates than Sc-PORP and remains stable over time.
Head ; Hearing ; Humans ; Incus ; Malleus ; Ossicular Prosthesis ; Ossicular Replacement ; Otitis Media ; Prostheses and Implants ; Stapes ; Tympanic Membrane

OBJECTIVE: To evaluate the results in patients who had ossicular chain reconstruction with a new type ossicular prostheses mixed bone morphogenetic protein and hydroxyapatite. METHOD: Analyze The effect of ossiculoplasty were analyzed in 59 cases. Ossiculoplasty using HA-BMP prostheses was performed in 26 ears,PORP was performed in 19 ears, TORP was performed in 7 ears. RESULT: The hearing success rate was 92.3% of 26 ears and no extrusion were found in HA-BMP group. There was a significant difference in mean postoperative air-bone gap between HA-BMP prostheses and autograft bone. CONCLUSION The new type HA-BMP prostheses can provide stable hearing results with high success rate over time.
Adult ; Bone Morphogenetic Proteins ; Bone Substitutes ; Female ; Humans ; Male ; Ossicular Prosthesis ; Ossicular Replacement ; Tympanoplasty

BACKGROUND AND OBJECTIVES: Hearing improvement after CWD tympanomastoidectomy is another major goal of surgery after eradication of disease, especially in cases with intact stapes. The objective of this study is to compare the postoperative results of hearing gain and middle ear condition according to the types of ossiculoplasty described above. SUBJECTS AND METHOD: Of patients who received CWD tympanomatoidectomy, 90 who had been followed up for more than 1 year after surgery were selected. We found 30 cases of classical tympanoplasty type III, 38 SC tympanoplasty cases, and 22 PORP tympanoplasty cases. Age and sex distribution, success rate of hearing improvement, mean of postoperative air-bone gap (ABG), rate of middle ear adhesion were analysed according to the type of surgery. RESULTS: At 3 months after surgery, success rates of hearing improvement were 37.0%, 51.4%, 57.1% for classical tympanoplasty type III, SC tympanoplasty, PORP tympanoplasty, respectively. Means of postoperative ABG in the above listed order were 25.1 dB, 19.4dB, 17.2 dB, respectively. Hearing results were statistically better in PORP tympanoplasty when compared with other groups (ANOVA with Duncan's multiple range test). At 1 year after surgery, success rates of hearing improvement were 21.1%, 35.5%, 64.7% in classical tympanoplasty type III, SC tympanoplasty, PORP tympanoplasty, respectively. Means of postoperative ABG in the above listed order were 29.1 dB, 20.3 dB, 16.7 dB, respectively. Hearing results were statistically better in PORP tympanoplasty compared with other groups (ANOVA with Duncan's multiple range test.). Rates of middle ear adhesion were 23.1%, 54.5% in classical tympanoplasty type III, tympanoplasty using strut, respectively. CONCLUSION: In cases with intact stapes in CWD tympanoplasty, we conclude that tympanoplasty using strut is more useful for hearing improvement and prevention of middle ear adhesion than classical tympanoplasty type III; for the strut material, we found PORP more effective than autologous materials.
Ear, Middle ; Hearing ; Humans ; Ossicular Prosthesis ; Sex Distribution ; Stapes ; Tympanoplasty

Humans ; Stapes ; Otosclerosis/surgery* ; Ossicular Prosthesis ; Stapes Surgery ; Incus

OBJECTIVETo design a tool for evaluating the sound transmission function of ossicular prosthesis and explore the impacts of ossicular prosthesis bead area and the effects of the mass of ossicular prosthesis on the sound transmission function in mechanical middle ear model.

METHODSTwo latex membranes were used to represent the tympanic membrane and oval window membrane. The ossicular prosthesis was fitted between the artificial tympanic membrane and oval window membrane during the test. Pure tune signals were used to stimulate the vibration of tympanic membrane. The vibration of oval window membrane was recorded by a laser Doppler vibrometer. The ossicular transmission function was evaluated by comparing the vibration velocities of oval window membrane. Two groups of titanium ossicular prosthesis with different head area and mass respectively were fitted into a mechanical middle ear model to evaluate their sound transmission functions.

RESULTSThe feeling threshold curve of mechanical middle ear model (MMEM) was similar to the hearing threshold curve of normal person. The transmission function of the prosthesis with small head area was better than that of prostheses with large head area at frequencies 1500-4000 Hz. The small-massed prostheses functioned better at higher frequencies and the large-massed prostheses functioned better at lower frequencies. But small-massed prostheses functioned better as a whole.

CONCLUSIONSThe MMEM was an idea tool to evaluate the transmission functions of different ossicular prostheses. Both the head area and prosthesis mass had an influence on the transmission function of ossicular prosthesis. So while designing the ossicular prosthesis or performing ossiculoplasty, both the head area and prosthesis mass should he taken into consideration.