1.A Case of NK/T-Cell Lymphoma Complicated by a Squamous Cell Carcinoma of Hard Palate during Combination Chemotherapy and Radiation Therapy.
Hang Lak LEE ; Myung Ju AHN ; Jung Hye CHOI ; Woon Hyun JUN ; Young Yuel LEE ; In Soon KIM ; Il Young CHOI ; Se Jin JANG ; Yong Wook PARK
The Korean Journal of Internal Medicine 2002;17(1):69-72
NK/T-cell lymphoma, which often shows an angiocentric growth pattern, is a distinct clinicopathologic entity highly associated with Epstein-Barr virus. The disease is characterized by a destruction of the upper respiratory tract, particularly the nasal cavity, palate and paranasal sinuses. Interestingly, NK/T-cell lymphoma is closely linked to a variety of complications, such as hemophagocytic syndrome, second primary cancer, sepsis and bleeding. Here we report a case of a 50-year-old man diagnosed initially as NK/T-cell lymphoma of the oropharynx and who developed a second primary carcinoma of the hard palate during combination chemotherapy and radiation therapy.
Carcinoma, Squamous Cell/*pathology/therapy
;
Case Report
;
Combined Modality Therapy
;
Fatal Outcome
;
Human
;
Killer Cells, Natural
;
Lymphoma, T-Cell/*pathology/therapy
;
Male
;
Middle Age
;
Neoplasms, Second Primary/*pathology/therapy
;
Oropharyngeal Neoplasms/*pathology/therapy
;
Palatal Neoplasms/*pathology/therapy
2.A case report of a secondary tonsil follicular dendritic sarcoma after non-Hodgkin's lymphoma.
Journal of Clinical Otorhinolaryngology Head and Neck Surgery 2014;28(6):428-429
Follicular dendritic sarcoma is a rare and low-grade malignant soft tissue tumors , often occurs in the lymph nodes, we report a case of tonsil follicular dendritic sarcoma which occured after Non-Hodgkin's lymphoma had be cured. The chief complaint was oropharyngeal foreign body sensation with hemoptysis three years, found in the left neck mass increased with more than 4 months. The left side of the pharyngeal wall thickening and disappearance of parapharyngeal space with the surrounding lymph nodes extremely enlarged and integrated was demonstrated by the contrast-enhanced CT of neck. Finally,the pathological diagnosis was tonsil follicular dendritic sarcoma.
Female
;
Humans
;
Lymph Nodes
;
pathology
;
Lymphoma, Non-Hodgkin
;
therapy
;
Neck
;
Oropharyngeal Neoplasms
;
diagnostic imaging
;
pathology
;
Palatine Tonsil
;
diagnostic imaging
;
pathology
;
Radiography
;
Sarcoma
;
diagnostic imaging
;
pathology
3.Mandibular swing procedure for surgical resection of advanced oropharyngeal carcinoma.
Jin XIE ; Pin DONG ; Bin JIN ; Ke-yong LI ; Jie WANG ; Li-qiang TU ; Jia ZHANG
Chinese Journal of Oncology 2007;29(4):302-304
OBJECTIVETo explore a better approach to resect the advanced oropharyngeal carcinoma.
METHODSFrom 1995 to 2005, 17 patients underwent mandibular swing procedure for excision of advanced oropharyngeal carcinoma including: 13 tonsillar cancers, 2 soft palate carcinomas and 2 lingual root cancers. Surgical procedure was selected according to the lesion. All tumors were resected through the mandibular swing approach or its combined approaches. Immediate reconstruction of the surgical defect was done using tongue flap, pectoralis major myocutaneous flap, sternohyoid myofascial flap, temporalis myofascial flap and forehead flap, respectively. After surgical resection of the tumors, all patients received postoperative radiotherapy.
RESULTSAll patients' advanced oropharyngeal carcinoma were successfully resected as planned through the mandibular swing procedure or its combined procedures without severe complications. Functions of deglutition, respiration and speech were well restored. The 3- and 5-year survival rate was 54. 5% and 40%, respectively.
CONCLUSIONThe mandibular swing procedure and its combined approach is safe and effective in the surgical resection of the advanced oropharyngeal carcinoma, which can provide a good exposure for the oropharynx, supraglottic region, hypopharynx, the parapharyngeal space and the base of the skull.
Adult ; Aged ; Carcinoma, Squamous Cell ; pathology ; radiotherapy ; surgery ; Combined Modality Therapy ; Female ; Humans ; Male ; Mandible ; radiation effects ; surgery ; Middle Aged ; Neoplasm Staging ; Oropharyngeal Neoplasms ; pathology ; radiotherapy ; surgery ; Postoperative Period ; Radiotherapy, Adjuvant ; Survival Analysis ; Tonsillar Neoplasms ; pathology ; radiotherapy ; surgery